ObjectiveTo identify the chemical composition of stem, leaf and peel ofCynanchumchinese R.Br..MethodsFourier IR spectra, the second derivative spectrum and two-dimensional correlation spectroscopy were adopted to identify IR of different parts ofCynanchumchinese R.Br..ResultsIt was found that the IR spectra of the leaf was similar to that of the peel but was different from the stem. What’s more, in the second derivative spectra of the leaf, it showed that the absorption peak was strong at the position of 1 543 cm-1, 1 515 cm-1, 1 499 cm-1 and 1 467 cm-1, respectively and there existed carbonyl absorption peak at 1 738 cm-1 and 1 659 cm-1 in addition. Therefore, it was inferred that flavonoids were the major components while less in the stem and peel.ConclusionsThe differences of the three parts aboutCynanchumchinese R.Br. were studied through IR spectrum macroscopically, which provided reference for exploring the constituents and clinical medication.

Objective To investigate the therapeutic effect of Xiaoxuan Kangfu capsule in treating psoriasis vulgaris. Methods All patients were divided into two groups randomly (60 patients in a control group and 60 patients in a treatment group). In the control group complex Qingdai capsule was given to the patients, with 4 pills for each time and 3 times daily. While in treatment group Xiaoxuan Kangfu capsule was given to the patients with 6 pills for each time and twice daily. 30 days consisted one treatment period for both groups. The patients undertook one to three treatment period according to the patients' pathogenetic condition. The rates of recovery and improvement and were compared. Results In the treatment group, 34 patients were cured (42.5%), and the total effective rate was 87.5%; while in the control group 14 patients were cured (7.5%), and the total effective rate was 72.5%. There was statistic difference between the two groups (P＜0.05). The average heal time of the treatment group was shorter than that of the control group, showing statistic difference (P＜0.05).Conclusion Xiaoxuan Kangfu capsule showed higher recovery rate, shorter healing time and lower recurrence rate in treating psoriasis vulgaris than complex Qingdai capsule. The treatment is deserving clinical spread.

BACKGROUND:Extracorporeal shock wave (ESW) therapy is using principles of liquid-electric conversion and transfer to produce energy gradient difference and torsional tension in tissues with varied density.It is a matured technique in treating urinary and digestive system calculosis.However,the applications of ESW in treating nonunion or delayed osseous union are few.OBJECTIVE:To explore the therapeutic effects of ESW in treating nonunion or delayed osseous union by animal experiment and clinical verification.METHODS:The effect of ESW on periosteal metabolism was explored by focusing extracorporeal wave on bone tissues,and the autoradiography of H~(3-)TdR labeling rate was observed by animal experiment.ESW was used to treat nonunion patients (n=16) or delayed osseous union patients (n=16),and the follow-uP results were evaluated.RESULTS AND CONCLUSION:By autoradiography,the H~(3-)TdR labeling rate was greater in the experimental sides than that of the control sides at 1 and 2 weeks after operation (P＜0.05-0.01),which confirmed that the mitotic activity of periosteal osteoblasts was increased,namely,endosteal osteogenesis was enhanced.Clinical verification results demonstrated that,at 16 weeks after operation,16 patients with delayed union were all cured,13 were cured among the 16 cases of nonunion,and the remained 3 cases had notably callus formation.No adverse events occurred in all cases.The results suggested that it is reliable to treat nonunion or delayed osseous union using ESW therapy.

Objective To investigate the effect of body mass index (BMI) on the clinical efficacy and prognosis of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD), and to provide evidence for the use of BMI in predicting their disease situation and prognosis.Methods Eighty patients with AECOPD admitted to the Department of Respiration of the Fourth Central Hospital of Tianjin from October 2014 to October 2015 were enrolled, and they were divided into low BMI group (BMI < 18.5 kg/m2) and normal BMI group (BMI 18.5 - 24.9 kg/m2) by difference in BMI. The differences in body height, body weight, blood gas analysis indexes [arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2)], lung function indexes [the percentage of the first second forced vital capacity/predicted value (FEV1%), the ratio of the first second forced vital capacity/forced vital capacity (FEV1/FVC)], hospitalization time, recurrence time and smoking index were compared between the two groups, the correlations between BMI and the indexes of blood gas analysis, pulmonary function, hospitalization time, recurrence time and smoking index in low BMI group were analyzed.Results The BMI (kg/m2: 21.09±2.03 vs. 16.39±1.26), PaO2 [mmHg (1 mmHg = 0.133 kPa): 63.59±4.95 vs. 56.54±3.23], FEV1% [(64.18±3.82)% vs. (59.82±5.73)%] and FEV1/FVC (63.83±3.20 vs. 59.28±3.63) in normal BMI group were all significantly higher than those in the low BMI group, PaCO2 in normal BMI group was significantly lower than that in the low BMI group (mmHg: 57.05±5.25 vs. 63.70±7.29). The results indicated that the patients in low BMI group had severer hypoxia and carbon dioxide retention than those in normal BMI group, and the lung function was also worse than that in the normal BMI group; the hospitalization time of normal BMI group was shorter than that of low BMI group (days: 11.70±2.36 vs. 15.25±2.80), and the recurrence time in normal BMI group was obviously longer than that of low BMI group (days: 93.78±57.85 vs. 48.58±17.85), smoking index in normal BMI group was markedly lower than that of low BMI group (year·branch: 2550.0±917.6 vs. 3652.5±1015.8), the differences were statistically significant (allP < 0.05). The linear correlation analyses showed that: BMI in low BMI group was positively correlated with PaO2, FEV1% and recurrence time (r = 0.557, 0.507, 0.455,P = 0.000, 0.000, 0.003), and was negatively correlated with PaCO2, hospitalization time and smoking index (r = -0.670, -0.405, -0.440,P = 0.009, 0.000, 0.005), and had no significant correlation with FEV1/FVC (r = 0.061,P = 0.707).Conclusion BMI is an important index for evaluating the severity and prognosis of patients with AECOPD.

Phacoemulsification cataract extraction and intraocular lens (IOL) implantation has become the mainstream treatment of cataract.But the postoperative residual astigmatism still influences the postoperative uncorrected visual acuity.Reduce residual astigmatism is currently the ophthalmologists' pursuit.The formation of the residual astigmatism is affected by various factors,which mainly associated with preoperative corneal astigmatism and surgically induced astigmatism.Except for the above reasons,residual astigmatism after Toric IOL implantation has its special reasons.Understanding the reasons of formation of residual astigmatism can provide us the methods how to reduce it.This paper reviewed the causes of the residual astigmatism after phacoemulsification cataract extraction and IOL implantation.

Objective:To establish a method for the determination of 8 residual organic solvents in tolterodine tartrate by capillary GC. Methods: The determination of methanol, ethanol, acetonitrile, acetone, ethyl acetate, trichloromethane and tetrahydrofuran in tolterodine tartrate dissolved in the solution of N, N-dimethylformamide-water ( 1∶ 4 ) was carried out on a CP-sil 5CB ( 60. 0 m × 0. 32 mm,5μm)column. The inlet temperature was 200℃ and the FID detector temperature was 250℃. The flow rate of carrier gas was 1. 2 ml·min-1 . The column temperature was 120℃. The headspace vial temperature was 85℃ and the time was 30min. The determina-tion of pyridine in tolterodine tartrate dissolved in the solution of dimethylsulfoxide-sodium hydroxide (17∶13) was carried out on an HP-1(30. 0 m × 0. 53 mm,5 μm) column. The inlet temperature was 220℃ and the FID detector temperature was 250℃. The column tem-perature was 80℃. The flow rate of carrier gas was 3. 0 ml·min-1 . The headspace vial temperature was 85℃ and the time was 30 min. Results:All peaks could be separated from each other under the chromatographic conditions. The linearity of the eight solvents was falrly good (r>0. 999). The average recovery was ranged from 86. 0% to 100. 2% with RSD of 1. 7%-3. 5% (n=9). The limit of detection was 0. 63, 0. 43, 0. 30, 0. 18, 0. 079, 0. 36, 0. 18 and 0. 89 μg·ml-1 , respectively. Conclusion:The methods can be applied in the determination of the eight residual organic solvents in tolterodine tartrate.

Objective To design a bandstop digital filter for cancelling the 50HZ noise. Methods Procedure and FDATool method were used in processing. Results The filter was tested by a blended sine wave, the experimental result showed that the filter could cancel the 50HZ noise. Conclusion This filter may eliminate a random noise except the 50HZ noise by modifying the procedure simply.

Intravascular stent has been widely used in clinic to treat cardiovascular diseases, but the complications gradually present. Vascular endothelialization following stent implantation is a key factor that influences the biocompatibility of material and human body. After stent implantation, vascular endothelium function is abnormal, inducing endodermis shedding, platelet aggregation, inflammatory reactions, vascular smooth muscle cell proliferation and migration, and excellular matrix formation. These pathological reactions cause in-stent restenosis. So repair and functional changes of vascular endothelial cells play an important role in in-stent restenosis. To deeply understand the vascular endothelialization following implantation of various stents, this paper discussed rapid vascular endothelialization by retrieving articles so as to search a method to solve this problem.

Being organelles present in higher plants and algae,and containing the entire machinery for the process of photosynthesis and their own genetic system,chloroplasts have played important roles in plant evolution.With the help of molecular approaches,the structure and sequences of chloroplast genomes have been studied to a large extent.The valuable chloroplast genomic information has been utilized in investigating plant evolution,diversity and phylogenetic relationships between different species.At the same time,chloroplast genome sequences are the essential information paving the road for successful chloroplast genetic engineering,which has shown considerable advantages compared with nuclear transformation and demonstrated its great potential in genetic improvement and the production of biopharmaceuticals.The latest developments in chloroplast genome analysis are reviewed,providing readers with insight into the fast growing field and facilitating a comprehensive understanding of the evolution,genetics and phylogenetic relationships among plants.It is also hoped to promote the further development of chloroplast technology and the commercial application of chloroplast transformation.

By introducing the job contents classification of hospital, the paper analyzes each sub-system including its information contents, structure features and construction factors, discusses the plan for establishing electronic medical records with combination of the component of medical records, from sequencing of the system, management mode, noted issues, moreover, suggests that each hospital should accord to own situation establishing own system.