1.Dual-energy CT technique and its clinical application on component analysis of urinary calculi
Peixiu LI ; Lijun DONG ; Rina DU ; Yuanyuan GENG ; Xincheng ZHANG ; Jianli LIANG
Chinese Medical Equipment Journal 2017;38(4):120-122,130
The history,hardware,imaging principle and technical characteristics of dual-energy CT machine were described.The causes,clinical diagnosis and treatment of urinary calculi were analyzed.Dual-energy CT had its technical characteristics,clinical significance,advantages and practicality expounded in detail when used to determine the components of urinary calculi.
2.Construction of a new model for evaluating insulin resistance in newly diagnosed type 2 diabetic patients using anthropometry parameters
Xincheng WANG ; Shi ZHANG ; Yi WANG ; Yanju ZHANG ; Meiyang DU ; Chunjun LI
Chinese Journal of Endocrinology and Metabolism 2023;39(7):575-580
Objective:To construct a new model for assessing insulin resistance(IR) in newly diagnosed type 2 diabetic patients by combining anthropometry parameters and biochemical parameters.Methods:A total of 677 newly diagnosed type 2 diabetic patients were included in this study. Clinical data, biochemical indicators, and body composition measurements were collected, and a predictive model was constructed using logistic regression analysis.Results:The IR prediction model was constructed based on five indicators: triglycerides(TG), fasting plasma glucose(FPG), visceral fat area(VFA), alanine aminotransferase(ALT), and uric acid(UA). The formula for the new predictive model was as follows: y=-17.765+ 1.389×ln VFA+ 1.045×ln UA+ 0.91×ln ALT+ 2.167×ln FPG+ 0.805×ln TG. The receiver operating characteristic curve(ROC) area under the curve(AUC) for the model was 0.82, with an optimal cutoff value of 1.67, sensitivity of 0.80, and specificity of 0.71. The AUC values for the triglyceride glucose(TyG) index, lipid accumulation product(LAP), and triglyceride/high-density lipoprotein cholesterol ratio(THR) were 0.75, 0.75, and 0.70, respectively. The corresponding sensitivities were 0.66, 0.84, and 0.71, and the specificities were 0.71, 0.59, and 0.60. The optimal cutoff values were 1.81, 30.31, and 1.14, respectively. Conclusion:The new model constructed using TG, FPG, VFA, ALT, and UA as indicators showed high predictive value and can serve as a new model for assessing IR in newly diagnosed type 2 diabetic patients.
3.Recent advances in emerging three-dimensional in vitro models for sport-related traumatic brain injury.
Xincheng DU ; Jibo WANG ; Wen ZHAO ; Pu CHEN ; Gaozhi OU
Journal of Biomedical Engineering 2021;38(4):797-804
Sports-related traumatic brain injury (srTBI) is a traumatic brain injury (TBI) caused by sports, which can result in cognitive and motor dysfunction. Currently, research on the molecular mechanism of srTBI and related drug development mainly relies on monolayer culture models and animal models. However, many differences exist in cell populations and inflammatory responses between these models and human pathophysiological processes. Most of the researches derived from the models can't effectively conducted translational research. Emerging three-dimensional (3D)
Animals
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Brain Injuries
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Brain Injuries, Traumatic
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Humans
4.Characteristics of Hypertension Death in Low-income Regions of Inner Mongolia, China.
Di YU ; Mao Lin DU ; De Jun SUN ; Su Fang QIAO ; Yu Jia MA ; Li WANG ; Yu Min GAO ; Yong Sheng CHEN ; Yong Liang MENG ; Xiao Ling SUN ; Wen Fang GUO ; Qing Xia WANG ; Hai Rong ZHANG ; Wu Yun Ta Na LI ; Lei JIA ; Jing HAO ; Neng Jun ZHAO ; Juan SUN
Biomedical and Environmental Sciences 2020;33(1):53-57