1.Perioperative Use of Antibacterials in Patients Undergoing C-sect:An Analysis of 753 Cases
Chenglu SHI ; Xinchao WANG ; Qunpu ZHOU
China Pharmacy 2005;0(23):-
OBJECTIVE:To investigate the perioperative use of antibacterials in patients undergoing C-sect.METHODS:The medical records of 753 cases between Oct.2005 and Mar.2007 were reviewed retrospectively.RESULTS:All the patients(100.00%)undergoing C-sect received antibacterials by iv gtt during perioperative period,and 99.07% were given at 0.5h before operation.Among all the antibacterials,73.31% were benzylpenicillin sodium.86.85% of the patients had a course of treatment of 2~3 days;93.36% of the antibacterials were used in single kind.As for the preventive medication outcome,the effective rate totaled 99.20%(694 CR+ 53 PR).CONCLUSION:The perioperative use of antibacterials in patients undergoing C-sect was rational on the whole.The antibacteirals were more often used singly for a course of 2 to 3 days.The low grade kind with low toxicity and cheap price is the preferred preventive medication for patients undergoing C-sect.
2.Effects of agaric polysaccharides on antioxidant capacity,serum immune indexes and intestinal flora of calves
Qiru WANG ; Yu ZHANG ; Guojun JIANG ; Haiyan LIU ; Xin HE ; Xinchao SHI ; Xing-Hua ZHAO
Chinese Journal of Veterinary Science 2024;44(6):1290-1298
This experiment was conducted to investigate the effects of agaric polysaccharides on an-tioxidant capacity,immune function,and intestinal flora of calves.Twenty-four healthy Holstein calves of(30±3)days of age and with the similar body weight at(55.33±1.86)kg were selected and randomly divided into two groups:the control group(group C)and test group(group T)with 12 replicates in each group and one calves in each replicate.Group C was fed starter and milk repla-cer,and group T was fed starter and milk replacer with 10 g of agaric polysaccharides to each calve for 10 d.Serum antioxidant,immune indexes and intestinal flora were tested.The results showed as follows:compared with group C,the enzyme activities of SOD and GSH-Px in serum of calves in group T were significantly increased(P<0.05),and were increased by 29.09%and 15.35%,re-spectively;compared with group C,IgA,IL-2 and TNF-α were significantly increased in T group(P<0.05).Adding agaric polysaccharides significantly increased the relative abundance of Firmi-cutes(P<0.05)and decreased the relative abundance of Proteobacteria in feces of calf(P>0.05);the relative abundance of Lactobalillus and Faecalibacterium were increased(P<0.05);the relative abundance of Butyricoccus-pullicaecorum was increased(P<0.05).LEfSe analysis results showed that there were 11 marker species in group T,such as Firmicutes and Lactobacillus,and 9 marker species in group C,such as Proteobacteria.The results showed that agaric polysaccharides could improve the antioxidant capacity and immune function of calves,and also could improve the structure of intestinal flora.