Objective To investigate pathologic changes and method of magnetic microsphere(Fe3O4) embolization for tumor.Methods 18 cases with tumors were treated by embolized using Fe3O4 under fluoroscopy through catheters by Seldinger’s technique,pathological examinations were done in 15 cases before operation,including primary hepatic carcinoma in 8,renal carcinoma in 6,renal myolipoma in 3 and breast carcinoma in 1.Results Pathological examination after embolism showed that necrosis of neoplastic tissue was 100 percent.Conclusion Fe4O4 is a good embolic substance for treating tumors and there is no damage to the other tissues.

Objective To investigate the clinical applied value of magnetic mitomycin microspheres and magnetic Fe 3O 4 in treating tumors and vascular diseases by embolism.Methods The embolic therapy in 106 cases useing microspheres or drugs of Fe 3O 4 under TV-guided through catheterization using Seldinger's technique were performed.Results In 94 malignant tumors and 12 benign vascular diseases.The most of tumors became small remarkably on CT,USG or BSA one month later after embolism.Pathology showed that necrosis of cancer tissue was 100 percent.Examination of blood biochemistry showed that the functions of liver and kidney had some changes,however these functions could recover to normal or better after therapy.AFP decreased significantly after embolism in most primary hepatic cancer.Changes in density of serum Fe before and after embolism showed that embolism of Fe 3O 4 microspheres could maintain serum Fe in normal condition.DSA showed that microspheres of Fe 3O 4 were moved from the near portion to the peripheral embolic arteries after embolism one month later and the clinical symptoes improved.Conclusion Fe 3O 4 is good embolic substance and can avoid some complications by embolism.

Objective To investigate experiment research of embolizing rabbits’ kidney arteries by using microspheres of Fe 3O 4 . Methods Kidney arteries in one side of 4 big white Newzeland rabbits had been embolized by using Fe 3O 4.Results Embolism of rabbits’ kidney arteries was safe and lasting . No reperfusion and lateral circulation were established. Conclusion Embolism with microspheres of Fe 3O 4 in kidney arteries is good and safe. It is valuable in clinical treatment.

Objective To investigate the mechanism and the clinical value of magnetic microsphere(Fe_3O_4) in embolizing tumor through artery catheter.Methods 94 patients with tumor were treated by embolized using Fe_3O_4 under fluoroscopy through catheters by Seldinger's technique.Of them,5 cases of hepatocellular carcinoma underwent magnetic field putting on outside the target area,pathological examination was done in 15 cases,25 cases underwent DSA examination one month later and the DSA images before and after operation were analysed statistically.Results Pathological examination after embolism showed that necrosis of neoplastic tissue was 100 percent.The statistical analysis of DSA images was in P

Objective To investigate the predictive factors and prognosis of early intrahepatic recurrence after curative resection of hepatocellular carcinoma(HCC).Methods Clinicopathological dats of 184 HCC patients with intrahepatic recurrence after curative resection were collected.Thirteen clinicopathological factors and prognosis after recurrence were retrospectively analyzed. Results Univariate analysis showed that preoperative scrota alpha-fetoprotein(AFP)>100 ng/ml,tumour size>5 cm,venous invasion and intra-operative blood transfusion were predictive factors of early intrahepatic recurrence,and selum albumin<35 g/L was marginally predictive factor.Multivariate analysis showed that serum AFP>100 ng/ml,tumour size>5 cm and venous invasion were independent predictive factots of early intrahepatic recurrence.The survival of patients suffering from early recurrence was significantly shorter than those with late recurrence.with median survival period of 12 mos vs 18 mos(P=0.012).Conclusion Serum AFP,tumour size and venous invasion were independent predictive factors of early intrahepatic recurrence in HCC patients after radical resection of the primary tumor.Early intrahepatic recurrence implies poor prognosis.

From November to December of 2018, twenty 65-year-old or older women patients with knee osteoarthritis were recruited from the Department of Physical Therapy, the First Affiliated Hospital of Anhui Medical University. Meanwhile, twenty healthy 65-year-old or older women were recruited from the local community. The results showed that the knee contact angle of the patient group was more flexed ( P=0.040), and the minimum angle of the knee joint increased ( P=0.008) during the stance period compared to the healthy group. However, there was no significant difference in the maximum contact angle between the angle of hip and ankle joints. In addition, the tibialis anterior muscle of the patients was significantly smaller than the healthy group ( P=0.023). Therefore, knee osteoarthritis could change the gait and muscle activity of older women, especially the knee joint.

From November to December of 2018, twenty 65-year-old or older women patients with knee osteoarthritis were recruited from the Department of Physical Therapy, the First Affiliated Hospital of Anhui Medical University. Meanwhile, twenty healthy 65-year-old or older women were recruited from the local community. The results showed that the knee contact angle of the patient group was more flexed ( P=0.040), and the minimum angle of the knee joint increased ( P=0.008) during the stance period compared to the healthy group. However, there was no significant difference in the maximum contact angle between the angle of hip and ankle joints. In addition, the tibialis anterior muscle of the patients was significantly smaller than the healthy group ( P=0.023). Therefore, knee osteoarthritis could change the gait and muscle activity of older women, especially the knee joint.

Objective To explore the clinical effect of personalized pars plana vitrectomy(PPV)for proliferative di-abetic retinopathy(PDR).Methods In this retrospective case study,76 patients(86 eyes)diagnosed with PDR and re-ceiving PPV in the Department of Ophthalmology of Songjiang Hospital affiliated to Shanghai Jiao Tong University School of Medicine,from October 2019 to November 2022,were divided into the observation group(40 patients,46 eyes)and the control group(36 patients,40 eyes).Patients in the obseration group were treated with personalized PPV,while patients in the control group were treated with conventional PPV,After treatment,all patients were followed up for 12 months.The operation time,intraoperative use of heavy water and silicone oil,incidence of iatrogenic retinal tears and heavy water resi-dues,proportion of scleral buckling,preoperative and postoperative best corrected visual acuity(BCVA)and intraocular pressure(IOP),retinal reattachment rate at 12 months after surgery,and the incidence of post-vitrectomy vitreous hemor-rhage(PVH),diabetic macular edema(DME)and neovascular glaucoma(NVG)were compared between the two groups.Results The operation time of patients in the observation group was shorter than that in the control group(P＜0.05).Intraoperative use of heavy water and silicone oil in the observation group was lower than that in the control group(both P＜0.05).The incidence of iatrogenic retinal tears and heavy water residues and the proportion of scleral buckling showed no statistically significant difference between the two groups(all P＞0.05).There was no statistically significant difference between the two groups in BCVA preoperatively,3,6 and 12 months postoperatively(all P＞0.05).BCVA in the observa-tion group was better than that in the control group at 1 day,1 week and 1 month after surgery(all P＜0.05).Compared with the preoperative value,BCVA increased in the observation group at 1 day,1 week,1 month,3 months,6 months,and 12 months after surgery(all P＜0.05);in the control group,BCVA increased slightly at 1 day and 1 week(both P＞0.05)and then increased significantly at 1 month,3 months,6 months,and 12 months after surgery(all P＜0.05).The two groups showed no statistically significant difference in IOP at 1 day,1 week,1 month,3 months,6 months,and 12 months postoperatively(all P＞0.05).There was no statistically significant difference in the retinal reattachment rate and the inci-dence of complications such as PVH,DME,and NVG between the two groups at 12 months postoperatively(all P＞0.05).Conclusion Personalized PPV can shorten the operation time,reduce the intraoperative use of heavy water and silicone oil,enhance the efficiency of the operation,and rapidly improve the visual acuity of PDR patients.

Chronic refractory wound (CRW) is one of the most challengeable issues in clinic due to complex pathogenesis, long course of disease and poor prognosis. Experts need to conduct systematic summary for the diagnosis and treatment of CRW due to complex pathogenesis and poor prognosis, and standard guidelines for the diagnosis and treatment of CRW should be created. The Guideline forthe diagnosis and treatment of chronic refractory wounds in orthopedic trauma patients ( version 2023) was created by the expert group organized by the Chinese Association of Orthopedic Surgeons, Chinese Orthopedic Association, Chinese Society of Traumatology, and Trauma Orthopedics and Multiple Traumatology Group of Emergency Resuscitation Committee of Chinese Medical Doctor Association after the clinical problems were chosen based on demand-driven principles and principles of evidence-based medicine. The guideline systematically elaborated CRW from aspects of the epidemiology, diagnosis, treatment, postoperative management, complication prevention and comorbidity management, and rehabilitation and health education, and 9 recommendations were finally proposed to provide a reliable clinical reference for the diagnosis and treatment of CRW.