1.The interventional therapy of airway dysplasia via bronchoscopy
Xin ZHANG ; Zhou FU ; Gang GENG
International Journal of Pediatrics 2016;43(12):934-937
Bronchoscopy is an indispensable method to diagnose and treat children with respiratory dis-ease treatment,it′s the foundation of pediatric interventional pulmonary procedures. Because of the widely use and the steady accumulation of clinical experience,the value has been consistently affirmative. This review de-scribes the interventional therapy of airway dysplasia via bronchoscopy.
2.Expression of coxsackie-adenovirus receptor in hearts of mice with experimental viral myocarditis and its regulatory mechanism.
Xiao-hua YU ; Ping ZHANG ; Xin-gang ZHANG
Chinese Journal of Pediatrics 2006;44(2):137-138
Animals
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Coxsackie and Adenovirus Receptor-Like Membrane Protein
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Coxsackievirus Infections
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genetics
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metabolism
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Disease Models, Animal
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Enterovirus B, Human
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pathogenicity
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Heart
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drug effects
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Immunohistochemistry
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Interleukin-1beta
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administration & dosage
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pharmacology
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Male
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Mice
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Mice, Inbred BALB C
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Myocarditis
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drug therapy
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genetics
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metabolism
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pathology
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virology
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Myocardium
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metabolism
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pathology
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RNA, Messenger
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Receptors, Virus
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genetics
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metabolism
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Reverse Transcriptase Polymerase Chain Reaction
3.A case report of endonasal meningoencephalocele complicated with abscess in brain and nasal cavity.
Huan-xin YU ; Jin-ling ZHANG ; Gang LIU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2011;46(5):423-424
Abscess
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complications
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Adult
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Brain Abscess
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complications
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Female
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Humans
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Meningocele
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complications
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Nasal Cavity
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pathology
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Nose Diseases
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complications
5.The effect of taking Preoperative oral clear water 2 hours before surgery on anesthesia induction and postoperative nausea and vomiting during pediatric interventional heart surgery
Weizhong HE ; Xin ZHANG ; Gang QIAN ; Xiaoqiang YAN ; Hongling MIAO
The Journal of Practical Medicine 2017;33(3):440-442
Objective To investigate the effect of different forbidden drink schemes on anesthesia induction and postoperative nausea and vomiting during pediatric interventional heart surgery.Methods One hundred and twenty pediatric patients underwent cardiac interventional procedures under general anesthesia were randomized into group A,B and C,with 40 patients in each group.Patients in cach group were fasted for 8 h preoperatively.Water was prohibited for patients in group A for 6 h preoperatively.Patients in groups B and C orally took 10% glucose solution and a multivitamin drink (Outfast) at 2 h preoperatively,respectively.Nausea and vomiting after anesthesia induction were recorded for 24 h postoperatively.Results The sedation and mask acceptance scores were significantly higher in group B and C than those in group A,and were significantly higher in group C than those in group B (P < 0.05,resoectively).Following anesthesia induction,MAP was significantly higher in group B and C than that in group A (P < 0.05,resoectively).Both the severity and incidence of postoperative nausea and vomiting were higher in group B and C than those in group A,and was lower in group C than that in group B (P < 0.05,resoectively).Conclusions Taking clear water orally 2 hours before surgery can decrease the restlessness of pediatric interventional heart surgery during anesthesia induction period,with stable smooth hemodynamics,reducing the degree of PONV.
6.Clinical value of urethral dilation in treatment of female bladder outlet obstruction
Baoguo LI ; Wensheng WANG ; Xin LI ; Gang ZHANG ; Jian XUE
Chinese Journal of Postgraduates of Medicine 2016;39(10):919-921
Objective To explore the clinical value of urethral dilation in treatment of female bladder outlet obstruction. Methods Thirty-five female bladder outlet obstruction patients were selected, and all the patients failed for more than 1 month inαreceptor blocker treatment. The patients underwent urethral dilation under local anaesthesia, once a week, for a total of 12 times. The international prostate symptom score (IPSS), quality of life score (QOL) and residual urine volume before and after treatment were examined. Results The IPSS, QOL and residual urine volume after treatment were significantly lower than those before treatment: (10.23 ± 6.31) scores vs. (21.41 ± 3.71) scores, (2.31 ± 0.65) scores vs. (5.43 ± 0.60) scores and (20.73 ± 10.59) ml vs. (85.23 ± 12.15) ml, and there were statistical differences (P<0.01). Conclusions The urethral dilation is one of the effective treatments for female bladder outlet obstruction patients who fail in αreceptor blocker treatment. It can make a part of patients avoid invasive examination and surgery, and it is worth to be popularized in clinic and primary hospital.
7.Clinical analysis of complications in children with cerebral palsy
Xin-Hua ZHANG ; Wei-Dong WANG ; Gang DING ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
Objective To investigate the prevalence rate of complications in children with cerebral palsy (CP).Methods 80 CP children were recruited.Their parents were interviewed for high risk factors and feeding his- tory.Each case was assessed neurologically for type of CP and diagnosed for complications.And all cases were detect- ed by magnetic resonance imaging(MRI)of the brain.Results Among 80 patients,60 cases(75%)suffered from complications,the majority patients had difficulty in taking in food,intelligence retardation,hearing impediment and vision impediment.The prevalence rate of complications with mixed CP was 85 %.MRI abnormalities of the brain were accounted for 74.5 % and periventrieular leakomalacia(PVL)was more common(45.1%).Conclusion This study suggested timely rehabiliatation and interventions must be started to significantly improve the levels of intelli- gence.And the epilepsy and nonepileptic events must be identified to avoid mistakes in diagnosis.
8.The efficacy of entecavir treatment on acute-on-chronic liver failure in patients with hepatitis B
Xin SHU ; Qihuan XU ; Ni CHEN ; Ka ZHANG ; Gang LI
Chinese Journal of Infectious Diseases 2009;27(5):281-286
Objective To evaluate the efficacy of entecavir treatment on hepatitis B patients with acute-on-chronic liver failure. Methods Eighty-four hepatitis B patients with acute-on-chronic liver failure were treated with entecavir 0.5 mg daily and Other routine drugs. Another 99 hepatitis B patients with acute-on-chronic liver failure were treated with only routine drugs as control. The survival, liver functions, hepatitis B virus (HBV) DNA level, prothrombin time (PT) were observed. The survival rates of patients with early, middle or late stage of liver failure were analyzed. The comparison of rates were done using chi-square test. The numeration data were compared by t test. The survival rates were compared using Kaplan-Meier method. Results Among patients with early stage of acute-on-chronic liver failure, the survival rate in treatment group was 63.3% (31/49), which was significantly higher than that in control group (39.7%, 23/58) (χ2=5.923, P=0.015). Among patients with middle stage of acute-on-chronic liver failure, the surviral rate in treatment group was 63.0% (17/27), which was significantly higher than that in control group (35.1%, 13/37) (χ2=4.854, P=0.028). Among patients with late stage of acute-on-chronic liver failure, four out of eight cases survived in treatment group, while one out of four cases survived in control group. In patients with serum total hilirubin (TBil) level > 342 μmol/L, the survival rate was 56.0% in treatment group, which was significantly higher than that in control group (26.8%) (χ2=9.351,P=0.002). At week 4 of the treatment, the HBV DNA reduction in treatment group was 3. 95 lg copy/mL, which was higher than that in control group (1.78 lg copy/mL) (t=5.847, P=0.001). Conclusions Entecavir treatment could improve the survival rate of hepatitis B patients with early or middle stage of acute-on-chronic liver failure. And the further study with larger population is needed in patients with late stage of liver failure. In addition, entecavir therapy could also improve the survival rate of patients with TBil >342 μmol/L.
9.Short-term Efficacy and Safety of Nedaplatin Combined with Docetaxel in the Treatment of Advanced Non-small Cell Lung Cancer
Yuanqiang HU ; Yongbo ZHANG ; Xin LI ; Gang XIONG ; Aihua LUO
China Pharmacy 2007;0(28):-
0.05).CONCLUSION:Nedaplatin combined with docetaxel is effective and safe for advanced NSCLC with high short-term efficacy and mild toxic side reaction in digestive tract and kidney.but the long-term efficacy of it require further study.