2.Test-retest Reliability Study in Hearing Loss Group of 18 Mandarin Monosyllable Lists with Equivalency in Audibility
Aiting CHEN ; Fei JI ; Xin XI ; Dongyi HAN
Journal of Audiology and Speech Pathology 2009;17(3):201-204
Objective To evaluate Test-retest reliability of Mandarin monosyllable lists with equivalency in audibility in hearing loss group. Methods Mandarin monosyllable lists were used to test 18 adults with moderate-to-severe sensorineural hearing loss. Each people was tested twice with an interval of several days and with same test conditions including same lists order, same presentation level, and same tester. List number to begin with was different between people. All test lists for one patient were presented by 30 dB above his hearing threshold levels. Recognition scores were recorded in both tests. The results were analyzed using SPSS. Results Pearson product-moment correlation between the scores of two tests was 0. 931 (P<0. 001). The average critical difference was 16.3 % at the 95 % confidence level after the scores transformed into "rationalized" arcsine unit (RAU). Conclusion The average critical difference is 16. 3% at the 95% confidence level which is less than in the normal hearing group. All the lists have good test-retest reliability, and can be used in extensive clinical practice.
4.The postoperative treatment of heart transplantation
Wei-Xin CHEN ; Shang-Yi JI ; Jian-An YANG ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To discuss the treatment after orthotopic heart transplantation and the experiences in deal- ing with ins complications.Methods To summarize the postoperative monitoring and management of 9 cases of patients af- ter heart transplantation.Results All 9 cases got out of hospital after recovery with better postoperative cardiac function and life quality.Among of them acute rejection appeared in 1 case earlier and 2 cases later after operation.1 case died later and 1 case had acute renal failure earlier after operation.Conclusion The effective monitoring for immunity and the scientific use of immunosuppressive agents after orthotopie heart transplantation,the active prevention and treannent of complications and its consanguineous follow-up are key factors for improving the survival rate.
5.Evaluation of Comprehensive Benefit of Hospital Pharmacy Department with Comprehensive Index Method
Jin YUAN ; Xin CHEN ; Bo JI ; Shujin ZHAO
China Pharmacy 1991;0(05):-
OBJECTIVE: To discuss the evaluation of comprehensive benefit of hospital pharmacy department with comprehensive index method. METHODS: Suitable evaluation indexes on social effects and economic returns were respectively selected to be assigned with weight numbers by analytic hierarchy process, and the comprehensive benefits of pharmacy department in our hospital during the period from 2002 to 2004 were evaluated. RESULTS: The index values of social effects, economic returns and comprehensive benefits increased year by year, which was in line with the objective actuality. CONCLUSION: It is feasible to evaluate comprehensive benefit of hospital pharmacy department with comprehensive index method.
6.The diagnostic value of axial loading imaging of the lumbar spine during CT and MR examination in patients with degeneration disorders
Xin-Wei LEI ; Jian-Zhong YIN ; Shuang XIA ; Xin-Juan CHEN ; Sheng-Yong WU ; Ji QI ;
Chinese Journal of Radiology 2001;0(08):-
15mm~2)of dural sac cross-sectional area to values smaller than 75 mm~2 was found during examination in axial loading,or if a suspected disc herniation,narrow lateral recess,narrow intervertebral foramen,or intraspinal synovial cyst changed to being obvious at the axial loading examination,they were regarded as additional information.Results After axial loading CT examination,AVI was found in 16 of 40 patients.A significant decrease of dural sac area was found in 13 patients.Intervertebral disc herniation was more severe in 7 patients,lateral recess or interverbral foramen narrowed in 4 patients,no intraspinal synovial cyst was found.After axial loading MRI examination,AVI was found in 19 of 60 patients.A significant decrease of dural sac area was found in 13 patients.Intervertebral disc herniation became severe in 10 patients,lateral recess or interverbral foramen narrowed in 8 patients,no intraspinal synovial cyst was found.AVI was found in 32 of 79(40.5%)patients with sciatica and 2 of 20(10.0%)patients with low back pain(?~2=7.45 P
7.Clinical analysis of management and pregnancy outcome of 248 patients with ovarian tumor and ovarian tumor like condition complicated with pregnancy
Yuexin YU ; Ju LI ; Hong CHEN ; Wei REN ; Dongying QU ; Jia CHEN ; Xin JI ; Lie WANG
Chinese Journal of Postgraduates of Medicine 2012;35(6):22-25
Objective To explore the clinical characteristics,management and pregnancy outcome in patients with ovarian tumor and ovarian tumor like condition complicated with pregnancy.Methods The clinical data of 248 patients with ovarian tumor and ovarian tumor like condition eomplicated with pregnancy who treated,operated and pathology conducted from January 2003 to December 2009 was analyzed retrospectively.Results Among of 248 patients,8 patients were found by pelrioscopy,184 patients were found by sonography.The rate of ovarian tumor and ovarian tumor like condition during pregnancy was 0.49% (248/50 652),about 52.82%(131/248)were diagnosed as benign tumor,most of them were ovarian mature teratoma(22.18%,55/248).About 45.56%(113/248)were diagnosed as ovarian tumor like condition,most of them were ovarian chocolatecyst(23.79%,59/248).Four patients(1.61%,4/248)were ovarian malignant tumor.Two hundred and sixteen received operation,term birth was in 164 patients,premature birth was in 19 patients,miscarriage was in 33 patients.Conclusions Pelvioscopy and sonogaraphy are principally important in the diagnosis and detection of ovarian tumor during pregnancy.Pregnancy complicated with ovarian tumor or ovarian tumor like condition should be treated by tumor resection.Suitable surgery intervention during second trimester is safe.
8.Effects of Tamm-Horsfall protein on kidney stone formation
Xin LIU ; Hongwei SU ; Jie CHEN ; Yongsheng ZHU ; Songtao LUO ; Meiying JI ; Kaifa CHEN ; Yiquan TANG
Journal of Medical Postgraduates 2017;30(9):922-925
Objective Tamm-Horsfall protein (THP) may play a role in kidney stone formation.The article aimed to conduct a preliminary study on the role of THP in kidney stone formation by investigating the changes of THP in rat urine, pathological changes of renal tissue and the formation of calcium salt crystals after establishing CNPs rat model of kidney stones.Methods Stone samples of 40 patients from February to June 2015 in our department were collected to establish the model of CNPs-induced kidney stone in rats and prepare CNPs suspension.48 SD rats were randomly divided into experimental group (group A) and blank control group (group B).Group A were injected with CNPs and the same amount of sterile saline injection in the group B.The urine of rats was collected after injection at 3h, 6h, 12h, 24h, 1w, 2w, 4w and 8w.ELISA were applied to detect THP levels in the urine.Then the rats were killed to take the kidney tissue.HE staining was used to investigate the pathological changes of the cells and evaluate the formation of the calcium salt crystals.Results THP levels in group A at 24h, 1w, 2w, 4w and 8w ([166.03±3.02], [173.50±1.78], [174.55±2.05], [176.54±2.45], [177.11±1.76]pg/mL) were significantly higher than that at 3h(165.89±2.23pg/mL)(P<0.05), which was the same case in comparison with those of group B ([157.65±2.22], [156.54±1.43], [159.45±3.21], [158.63±2.98], [157.33±2.05]pg/mL).Compared with the calcium salt crystal score at 6h (1 point), the scores at 3,6,12,24h (average score 2 points) increased.At 2w the score increased significantly to 3 points and reached the top score(6.7points) at 8w, which was of significant difference.The score of calcium salt crystals was in positive correlation with THP content (r=0.843,P<0.05).Conclusion THP in urine may contribute to the aggregation of calcium salt crystals and the formation of kidney stones.
9.Differentiation-inducing effects of baicalin on HL-60 leukemia cells
Bu-Yuan CHEN ; Jian-Da HU ; Xin-Ji CHEN ; Lian-Huang LV ;
Chinese Journal of Pathophysiology 2000;0(08):-
AIM:To investigate the differentiation-inducing effects of baicalin on HL-60 leukemia cells.METHODS:The effect of baicalin on differential induction in AML cell line HL-60 was evaluated by cellular morphology,clone formation assay,CD11b and CD33 expression and NBT assay.RESULTS:Baicalin inhibited the proliferation of HL-60 cells.It enhanced the expression of CD11b on HL-60 cells,also increased the expression of CD33.HL-60 cells showed differentiation morphology after the drug treatment examined by Wright-Gimesa staining and NBT assay.CONCLUSION:Baicalin possessed differentiation-inducing effects on HL-60 cells.
10.The effects of different amounts of iodine intake on the immune status of patients with Graves disease
Junping SU ; Shengou SU ; Bo ZHANG ; Yunxia CHEN ; Chunyan LIU ; Shujun JI ; Xin YU ; Fang BIAN
Clinical Medicine of China 2012;28(1):44-46
ObjectiveTo investigate the effects of different amounts of iodine intake on the cellular and humoral immune in Grave's disease (GD) patients.MethodsThe clinical GD cases were diagnosed by thyroid fine needle Cytology examination.Patients in GD group are divided into GD group Ⅰ and GD group Ⅱ based on the median of urine iodine.The blood levels of FT4,FT3,TSH,TPOAb,TGAb,TRAb and TNF-t were detected.The difference and association of these parameters between these groups were analyzed.ResultsThe TNF-αt level in GD Ⅰ group was higher than that of GD Ⅱ group( P > 0.05 ) ;The average level of TRAb of GD Ⅰgroup ( [ 1.4 ±0.2 ] U/L) were higher than that of GD Ⅱ group ( [ 1.2 ± 0.1 ] U/L) ( P < 0.05 ) ;The positive rates of TGAb and TPOAb of GD Ⅰ group were higher than that of GD Ⅱ group ( P < 0.05 ).The percentages of patients with high level of TGAb and TPOAb in GD Ⅰ group ( 78.9% 、84.2% ) were higher than that in GD Ⅱ group (50.0%,62.5% ) ( x2 =6.79,10.70,P <0.05 ) ; Analysis showed a linear positive correlation of TNF-αwith TRAb and TPOAb ( r is 0.489 and 0.563,P < 0.01 ).ConclusionIodine is an important factor to the development of Graves disease.Excessive iodine intake will exaggerate the GD condition and patients with GD should be controlled for iodine intake.