1.The preliminary study of the effect of ritodrine on the change of heart rate in threatened premature labor.
Chinese Journal of Practical Gynecology and Obstetrics 2001;17(4):228-230
Objective To determine the change of maternal heart rate during the treatment with ritodrine for threatened premature labor. Methods110 cases of threatened premature labor were chosen. The ritodrine 100mg in 5% G. S 500mL was intravenously administered. The initial dosage was 6 drops/min, and the dose was increased until uterine contractions were inhibited. The treatment lasted for 40 to 48 hours after the uterine contractions were inhibited, then the oral tablets was recommended. If necessary, repeated treatment was given to some patients. The maternal heart rate was recorded in the whole process of treatment and was compared with the dosage administered. The labor time, fetal weight and Apgar′s score were also analyzed. Results The maternal basic heart rate was increased at first and then decreased. The increasing significantly increased( P < 0.01 ) when the uterine contraction was inhibited. , but no difference showed among the groups of different gestational age( P>0.05 ). The maternal heart rate was increased with the increasing of ritodrine( max. 140/min). labor time was significantly prolonged with the treatment of ritodrine( P<0.01 ) ,while that of the idiopathic premature labor was prolonged most obviously ( P < 0.05 ). Average fetal weight was (2.42 ± 0.49) kg, and the average Apgar′s score was≥8. Conclusion In the treatment of inhibiting uterine contractions,the increasing of maternal heart rate caused by ritodrine can be used as an indicator of therapeutic effect.
3.Pharmacologic action of the Magnolia biondii Pamp volatile oil nanometer bangosome
min, WU ; wei-wei, LU ; xin, ZHANG
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(04):-
Objective To investigate the pharmacologic action of the Magnolia biondii Pamp volatile oil nanometer bangosome. MethodsThe pharmacologic action of the Magnolia biondii Pamp volatile oil nanometer bangosome was evaluated by observing its effect on Jimpy mice with swelling ear,capillary permeability and rats with allergic symptoms. Results The Magnolia biondii Pamp volatile oil nanometer bangosome could significantly relieve the degree of swelling in Jimpy mice extended by p-xylene,inhibit the increased capillary permeability in Jimpy mice extended by HAC,and combat the symptoms of rhinocnesmus,sneezing,nasal discharge with a better effect than the Magnolia biondii Pamp volatile oil. Conclusion The Magnolia biondii Pamp Volatile oil nanometer bangosome has a good anti-inflammation and anti-hypersensitiveness effect,which upgrades the effect of the Magnolia biondii Pamp volatile oil.
4.Imaging swallowing dysfunction among patients recovering from severe traumatic brain injury
Xin ZHANG ; Wei WANG ; Hao ZHANG
Chinese Journal of Physical Medicine and Rehabilitation 2012;34(8):573-578
Objective To explore the utility of videofluoroscopy in observing swallowing dysfunction after severe traumatic brain injury (TBI). Methods Videoflouroscopic studies of swallowing (VFSSs) were performed on 40 patients with severe TBI as well as 40 healthy matched controls.Information about penetration and aspiration was collected,and oral delay time (ODT),oral transit time (OTT),pharyngeal delay time (PDT),pharyngeal transit time (PTT) and the maximum vertical and anterior movement of hyoid bone were measured. Results Seventeen of the healthy controls (42.5%) displayed mild penetration,though none had severe penetration or aspiration.Among the severe TBI patients,5 ( 12.5% ) displayed mild penetration,12 (30.0%) showed severe penetration and 17 (42.5%) subjects had aspiration.The 3ml liquid swallowing parameters of the severe TBI group were ODT ( 0.86 ± 0.37) s,OTT (0.73 ± 0.28 ) s,PDT ( 0.50 ± 0.35 ) s and PTT(0.61 ± 0.11 ) s.The maximum vertical hyoid bone movement in this group averaged (0.98 ± 0.38) cm,and maximum anterior movement was (0.37 ±0.37) cm.The healthy controls and severe TBI patients showed significant differences in terms of all six measures.Conclusion Dysphagia was found to be frequent among severe TBI patients,commonly occurring in the oral and pharyngeal phases.Videoflouroscopy may be helpful for identifying the main features of dysphagia and formulating better rehabilitation strategies.
5.Investigation on Education Content and Ways of Learning for Short Term Standardization Training in Advanced Training Nurse
Aili XIN ; Huanhuan WEI ; Chunmei LEI ; Xia XIN ; Yinping ZHANG
Chinese Medical Ethics 2015;(4):599-601
Objective:To seek the short term standardization study nurses training education content and the ap-proach to learning, provide theoretical basis for improving the study effect of nurse training.Methods:Choosing 3 ~6 months in 2014 in our hospital study questionnaire survey was conducted among 114 nurses, questionnaire by general in-formation, content of training needs, demand method of three parts and using SPSS19.0 to analyze the collected data. Results:The 82.7%of study nurses think pre-service training is very necessary.Pre-service training demand of the top three comprises:occupational protection (82.7%), health care, with communication skills (80.0%) and infection prevention and control (78.2%).Refresher training needs during the top three in turn:specialized rescue of critically ill patients and cooperation (88.2%), clinical application and nursing adverse event processing (79.1%), effective communication nurses and patients (79.1%).Demand content score between the different degree and the title of ad-vanced nurse was statistically difference (P<0.05).The training methods, in the first three order practice (89.10%), seminar (74.5%), case analysis and discussion (67.30%).Conclusion:According to the study demand of nurse stand-ardized training content and ways of learning, considering the influence factors such as education, job title, targeted training plan, improve the effect of short-term training.
6.Clinical analysis of ten cases of congenital middle ear cholesteatoma.
Xin XIN ; Wei LU ; Shuping SUN ; Jing ZHANG ; Yibo LEI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(7):443-445
OBJECTIVE:
To investigate the clinical features and operation treatment of the congenital middle ear cholesteatoma.
METHOD:
A retrospective review of clinical and surgical records of 10 patients with congenital middle ear cholesteatoma were performed. All patients were treated by surgeries,5 of 10 cases deal with one-stage tympanoplasty after drum exploration by external auditory meatus, 3 cases dealed with closed mastoidotympanectomy and tympanomastoidectomy, 2 cases dealed with open mastoidotympanectomy and tympanomastoidectomy.
RESULT:
The cholesteatomas were located at or around the posterior tympanum or mesotympanum in 5 patients, confined to the tympanic cavity and attic in 3 patients, advanced cholesteatoma that extended from the tympanic cavity into the mastoid antrum was seen in 2 patients. The mean postoperative PTA was 30 dB HL, the mean ABG was within 20 dB, after six months. No residual or recurrence of cholesteatoma was found.
CONCLUSION
The congenital cholesteatoma often originates from the posterior or anterior of the middle ear, with hiding lesion, thus result in severe conductive hearing loss. Imaging examination plays an important role in diagnosing and treating of congenital cholesteatoma. Early stage surgical treatment can obtain a good hearing reconstruction effect.
Adolescent
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Adult
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Child
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Child, Preschool
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Cholesteatoma
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congenital
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surgery
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Cholesteatoma, Middle Ear
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surgery
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Ear, Middle
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physiopathology
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Female
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Follow-Up Studies
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Humans
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Male
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Retrospective Studies
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Tympanoplasty
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methods
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Young Adult
7.A Follow-up Study on Recovery Process of Postpartum Depression
Xin ZHANG ; Wei XI ; Rujuan MIAO
Chinese Mental Health Journal 1988;0(06):-
Objective: To explore the recovery process and the influence factors of post-partum depression (PPD) .Methods:22 women with PPD and 34 women of non-PPD were investigated with the Edinburgh Postnatal Depression Scale (EPDS) and the Delivery Woman General Situation Questionnaire (DWGSQ) at 18 months and 30 months after childbirth.Results:The EPDS scores of PPD (11.27?3.49 at 18 months;10.91?4.59 at 30 months) were significantly higher than that of non-PPD (7.59?3.83 at 18months;7.47?4.09 at 30 months) (t 1=3.636, P 1
8.The management of femoral shaft fractures with ipsilateral femoral neck fractures
Jingyi XIN ; Tieliang ZHANG ; Wanfu WEI
Chinese Journal of Orthopaedic Trauma 2002;0(03):-
Objective To analyze the clinical characteris tics and diagnostic outline and to elucidate the effects of different managements of femoral shaft fractures with ipsila teral femoral neck fractures.Methods A retrospective study was carried out in 18patients with ipsilateral femo ral neck and femoral shaft fractures from 1998to 2001,and their managements and final clinical outcomes were reviewed.Results The follow -up ranged from8to 40months with an average of 16mon ths.All the fractures united except one femoral shaft fracture and one femoral neck fracture.Conclusion Retrograde intramedullary nailing with multiple cancellous screws to t reat ipsilateral femoral neck and femora l shaft fractures has been proved an e ffective technique.For the cases overlooked initially,treatment with multiple nailing around the intramedullary n ail is a good choice.[
9.Clinical Effect of Electrochemical Therapy on Hemangiomas of Liver.
Jinghong LI ; Yuling XIN ; Wei ZHANG
Journal of Medical Research 2006;0(05):-
Objective To explore the clinical effect of electrochemical therapy (EchT) on hemangiomas of liver.Method 186 cases of hemangiomas of liver with,male 97 and female 89 were selected for the study.The age ranged from 31~55 years old.The electrochemical therapy instrument of model ZAY-B and the electrode made of platinum were used.Suitable manipulating technique and treating quantity of electricity were investigated for the patients.Electrodes were inserted into the tumor through a tracer directly by opening the abdominal cavity.Normal tissue of liver was protected by the spaghetti and the electrodes were connected to EchT device,then the treatment began.The therapeutic voltage was 6~8V,electic current 120~160mA.The quantity of electricity was 100~150 Coulombs per 1.0cm diameter of the tumor.The treatment could be terminated when the tumor became from soft to stiff.Result The therapeutic efficacy was evaluated 6 months after EchT.Through the follow-up of 1~5 years,103 of total 186 cases of hemangiomas of liver completely disappeared(72.5%);31 cases partially relieved (21.8%) and 8 cases were ineffective (5.6%).Conclusion EchT to treat hemangiomas of liver is safe and efficacy,with less traumatic and a quick recovery.It can be served as a new method for treating hemangiomas of liver.
10.Clinical experience on diagnosis and treatment for 10 cases of hepatic space-occupying lesion with CTA,CTAP and lipiodol CT
Wangao ZHANG ; Wei XIN ; Jie HUANG
Chinese Journal of Primary Medicine and Pharmacy 2006;0(07):-
Objective To investigate the significance of qualitative diagnosis and guidance on treatment for hepatic space-occupying lesion with combined use of CTA,CTAP and lipiodol CT,thus discuss some related questions.Methods By Seldinger technique,10 patients were examined with combined use of CTA,CTAP and lipiodol CT.Results 7 undiagnosed cases were given definite diagnosis through CTA,CTAP and lipiodol CT,3 cases were guided to surgery and intervention therapy and 1 case was detected metastatic sites in time.Conclusion Combined use of CTA,CTAP and lipiodol CT has important significance for the qualitative diagnosis of hepatic space-occupying lesion,and has important value in guidance on surgery and intervention therapy for the patients with hepatic carcinoma.