2.Analysis and treatment of the recurrent retinal detachment after silicone oil injection.
Xin XIE ; Zhi-qing CHEN ; Yan WENG
Journal of Zhejiang University. Medical sciences 2003;32(2):159-161
Adult
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Aged
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Female
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Recurrence
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Retinal Detachment
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etiology
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surgery
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Silicone Oils
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therapeutic use
3.Changes of the expression of adhesion molecules on CD34~+ cells during the rhG-CSF mobilization
Jianyu WENG ; Xin DU ; Jianjun ZHANG
Chinese Journal of Blood Transfusion 1988;0(02):-
Objective To study the changes of the expression of adhesion molecules on peripheral blood CD34+ cells during recombinant human granulocyte colony stimulating factor(rhG-CSF) mobilization,and to study the influence of rhG-CSF on donors.Methods Fifteen healthy blood donors were subcutaneously injected with rhG-CSF(10?g?kg-1?d-1)for 4 to 6 days.The expressions of very late antigen 5(VLA-5,CD49e) and L-selectin(CD62L) on CD34+ cells were examined by flow cytometry before mobilization,the fourth day during mobilization and the seventh day after mobilization.Results The percentage of CD34+ cells,especially CD34+CD49e+ cells,increased significantly during mobilization,reaching the peak on the forth day,but declined to normal level when the mobilization stopped.The percentage of CD34+CD62L+ cells didn't show any significant change during the mobilization.Conclusion rhG-CSF could increase the percentage of CD34+CD49e+ cells in peripheral blood,but the percentage was reduced one week after the mobilization.rhG-CSF doesn't affect the percentage of CD34+CD62L+ cells.
5.Association of coronary heart disease with two polymorphisms within C reactive protein gene promoter region in ethnic Han Chinese
Xin ZHAO ; Liang WENG ; Yao XIAO ; Jianping CAI
Chinese Journal of Practical Internal Medicine 2001;0(04):-
Objective To investigate the distribution of two single nucleotide polymorphism(SNP)-717A/G and-390C/A/T-within the C reactive protein(CRP)promoter region in ethnic Han Chinese and the association with coronary heart disease(CHD).Methods Altogether positive CHD patients and negative controls were studies in this study.The two target fragments were amplied by PCR.Then the-717A/G polymorphism was screened by restriction fragment length polymorphism(RFLP)and the-390C/A/T polymorphism by Sequence Specific PCR(SSP).At last,the association was studied by proper statistical analysis.Results There was no significant difference in the distribution of-717A/G polymorphism betweenpatients and controls.However,the frequencies of allels in-390C/A/T polymorphismwere significant different between them(P
6.Clinical application of CT virtual cystoscopy
Siqi WANG ; Xin JIANG ; Hongde CHEN ; Zhiliang WENG
Chinese Journal of Postgraduates of Medicine 2008;31(35):8-10
Objective To evaluate the clinical application of CT virtual cystoscopy (CTVC). Me-thods Thirteen patients who had clinical indication were studied. Iodine contrast was intravenously injected after the bladder was voided. Thin-slice spiral CT scanning of the bladder area was started when the bladder became filled with contrast media. By using 3D navigator smooth software, CTVC images were obtained. The findings in all cases were compared with the cystoscopy and surgical results. Results Nine patients with CTVC were proved vesical tumor,3 patients with CTVC were proved benign prostatic hyperplasia, and they were confirmed by cystoscopy,1 patient with cystitis glandularis could not be diagnosed with CTVC.By CTVC, the diagnostic accordance rate was 92.3%,the coincidence rate was 100.0% in vesical tumor. Conclusions CTVC is highly sensitive in displaying the vesical lesions.Being a new and non-invasive technique, CTVC is very helpful in the diagnosis of introvesical diseases. It has fine value in the clinical practice.
7.Analysis of the factors related to esophageal injuries in radiotherapy of esophageal cancer.
Jian WU ; En-le CHEN ; Xin-ran WENG
Chinese Journal of Oncology 2011;33(5):375-376
Aged
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Carcinoma, Squamous Cell
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drug therapy
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radiotherapy
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Combined Modality Therapy
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Esophageal Diseases
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etiology
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Esophageal Neoplasms
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drug therapy
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radiotherapy
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Female
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Fluorouracil
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administration & dosage
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Particle Accelerators
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Platinum Compounds
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administration & dosage
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Radiation Injuries
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etiology
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Radiotherapy, High-Energy
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adverse effects
9.Clinical observation of performing rhegmatogenous retinal detachment surgery under operation microscope
Zhi-Xin, SHEN ; En-Fang, GAO ; Wen-Qing, WENG
International Eye Science 2015;(2):339-341
To compare the effect and advantage of performing rhegmatogenous retina detachment surgery under operation microscope with under direct ophthalmoscopes .METHODS: Ninety - three patients ( 93 eyes ) were randomized to two groups, Group A ( under operation microscope during rhegmatogenous retina detachment surgery, 47 cases ) , Group B ( under direct ophthalmoscopes during rhegmatogenous retina detachment surgery, 46 cases ) . All patients were followed up for 2wk to observe success rate and visual improving rate.RESULTS: Total percentage of success was 95. 74% in group A and 80. 43% in group B. The visual improving rate of group A was 82. 98% and it was 67. 39% in group B. Operative time in group A was significantly shorter than that in group B (P<0. 05). CONCLUSlON: Performing rhegmatogenous retina detachment surgery under operation microscope is ascertaining and it is more effective and handy than performing that surgery under direct ophthalmoscopes.
10.A fMRI Study of Cortical Reorganization in Chronic Stroke Hemiplegia Treated with Constraint-induced Movement Therapy
Bo WEN ; Lin MA ; Changshui WENG ; Zhixin ZHENG ; Tong XIN
Chinese Journal of Rehabilitation Theory and Practice 2008;14(4):366-367
Objective To investigate the evidence of cortical reorganization in stroke hemiplegia treated with constraint-induced movement therapy(CIMT)by fMRI.Methods Five patients with chronic stroke were evaluated with the Action Research Arm Test(ARAT).The functional MRI(fMRI)was performed on a 3.0-T MRI with echo-planar imaging.The subjects were required to finish the finger-tapping task and undergo fMRI before and after CIMT.A block design was used for the inspection.Results After CIMT,the function of upper limb(sick side)of patients improved significantly assessed by ARAT(P<0.001),and cortical reorganization was found on fMRI.Conclusion CIMT can improve motor function of upper limb of chronic stroke patients with hemiplegia and induce cortical reorganization as measured by fMRI.