1.The Study on Teaching and Experiment of Acupuncture andMoxibastion Science under the Internet Environment
Chinese Journal of Medical Education Research 2003;0(04):-
This article explains in detail the experiment of the education transformation of acupuncture and Moxibastionscience, which is based on the use of internet resources, and the assessment method of education results. The article alsostresses the importance of using the above method to enhance education reformation in the universities of the traditionalChinese medicine, to change the education mode and to improve the education quality.[
2.Practice of Constructivism Learning Theory in Network Teaching of Acupuncture and Moxibustion Science
Chinese Journal of Medical Education Research 2006;0(09):-
According to the constructivism learning theory,the paper analyzed the method and the value of applying the constructivism learning theory to teaching Acupuncture and Moxibustion Science in the universities and colleges of Chinese medicine from designing and developing the pedagogy platform and online learning courseware for Acupuncture and Moxibustion Science to the experiment of teaching mode and the effect on teaching experiment based on constructivism learning theory etc.The advantages and effect are also summed up in this article.
3.Effect of CT localization needing around the lesion area at skull on the concomitant symptoms and hemorheological changes in stroke patients during restoration period
Chinese Journal of Tissue Engineering Research 2006;10(3):140-142
BACKGROUND: Vascular dementia is a syndrome characterized by cognitive impairment, which is induced by ischemic or hemorrhagic apoplexy or ischemic-anoxic brain injury. It is assigned to "imbecility", "dementia", "sluggish consciousness", "susceptible to forget things" etc. By traditional Chinese medicine. Impairments of memory and cognition etc. Caused by dementia seriously affect psychosomatic health and quality of life of elderly people.OBJECTIVE: To observe the effects of shuanggen cephalocathartic decoctum on learning, memory and spatial discrimination ability of vascular dementia rats.DESIGN: Randomized control trail taking experimental animals as objects.SETTING: Teaching and Research Section of Basic Theory of Traditional Chinese Medicine, Preclinical Medicine College, Nanjing University of Traditional Chinese Medicine.MATERIALS: The experiment was performed in Laboratory of Viscerastate of Teaching and Research Section of Basic Theory of Traditional Chinese Medicine, Preclinical Medicine College, Nanjing University of Traditional Chinese Medicine, from January to February 2004. A total of 40 male SD rats were selected and randomly divided into sham operation group, model group, model plus traditional Chinese medicine group and model plus Western medicine group, with 10 in each group. Before the experiment, all the rats were adaptively fed for one week, free drinking and eating before and during the experiment. Medicine and reagent are shuanggen cephalocathartic decoctum and Nimotop tablet, and main experimental apparatuses are DTT-2 jumping apparatus and SMG-2 water maze apparatus.METHODS: Blood was collected from left ventricle under aseptic condi tion, and dried in incubator at 37 ℃, after trituration, it was sifted with sieve of 200μm meshes and embolus was prepared. 1 mg embolus and 0.3 mL physiological saline was mixed and shaken up into suspension. Common carotid artery was temporarily occluded with a vascular clamp, and external carotid artery was retrogradely intubated and the embolus suspension was injected into encephalon to establish model of multiple cerebral infarction. In sham operation group, canulate tubule was intubated only to the bifurcation of common carotid artery, with no fluid injected in. Before the experiment, rats in model group and sham operation group were normally fed, while rats in model plus traditional Chinese medicine group were additionally given shuanggen cephalocathartic decoctum [4 g/(kg·d)] infusion and rats in model plus western medicine group were additionally given Nimotop [2 mg/(kg·d)] infusion, once a day for consecutive 15 days. Passive escape jumping experiment was conducted on rats in each group on the 9th day.Recorded the reaction time for rat jumping onto the rubber cushion after electric shock and the frequency of mistakes of suffering electric shock due to jumping down from the platform in 3 minutes, and took the results as learning indexes. The test was repeated on the 10th day. Put the rat into the box for 3-minture adaptation, then put it on the rubber cushion; recorded the latency for rat first jumping down from the rubber cushion and the frequency of jumpingdown from the rubber cushion in 3 minutes, and took the results as memory indexes. Water maze spatial discrimination experiment was conducted on rats in each group on the 11th day, recorded the frequency of mistakes of rats entering dead end and the latency for landing on safe platform. Every time, took a 40-second rest after swimming. Each rat was trained 10 times a day for consecutive three days. MAIN OUTCOME MEASURES: Results of passive escape jumping experiment and water maze spatial discrimination experiment. RESULTS: Each group had a rat dead in the process of operation except sham operation group in which all rats moved normally. Totally 37 rats entered results analysis. ① Results of passive escape jumping experiment: On the 9th day, compared with model group, the reaction time of rats in sham operation group, model plus traditional Chinese medicine group and model plus western medicine group significantly shortened (P < 0.01 -0.05), the frequency of mistakes in 3 minutes remarkably decreased in sham operation group and model plus traditional Chinese medicine group (P < 0.05); on the 10th day, the latency was significantly prolonged in sham operation group as compared with model group (P < 0.05); compared with model group, the frequency of mistakes in 3 minutes significantly decreased in sham operation group, model plus traditional Chinese medicine group and model plus western medicine group (P < 0.05). ② Results of water maze spatial discrimination: On the 3rd day, compared with model group, the frequency of mistakes of rats entering dead end significantly decreased in sham operation group, model plus traditional Chinese medicine group and model plus western medicine group (P < 0.001-0.05); the frequency of mistakes in model plus traditional Chinese medicine group obvi ously decreased as compared with model plus western medicine group (P < 0.05). During the 2nd and 3rd days of water maze experiment, the time for the rat reaching terminal was significantly shortened in sham operation group, model plus traditional Chinese medicine group and model plus western medicine group as compared with model group (P < 0.05).CONCLUSION: Shuanggen cephalocathartic decoctum can significantly improve learning and memory ability of rat model of vascular dementia, and is more effective than Nimotop in the aspect of improving spatial discrimination ability of rat.
4.Research in Teaching Mode Based on Website of On-line Study of "Acupuncturology"——Experimental Investigation in Educational Reform Based on Utilization of On-line Rescources of "Acupuncturology"
Xin LUN ; Zhanpeng ZENG ; Li RONG
Chinese Journal of Medical Education Research 2002;0(01):-
Under the guidance of the learning theory of constructivism,the mode of curriculum educational reform is designed and experimented on the"acupuncturology" on-line study website using the method of action research.The action experiment contains 3 kinds of different teaching modes: the teaching center mode,the study center mode and teacher donimated-students centered mode.A whole process intervention to question senses is carried on.The relative theoretical basis and problem-solving research methods are found out during the experiment.Phase summary is formed and the teaching project is constantly revised and become perfect.
5.Treatment of Skin Pruritus with Auricular Acupuncture
Xin LUN ; Li RONG ; Guoqi HUANG
Journal of Acupuncture and Tuina Science 2004;2(1):21-22
Auricular points of Lung (MA-IC1), Fengxi (MA-SF), EarShenmen (MA-TF1), Subcortex (MA-AT1), Adrenal Gland (MA-T) and Large Intestine (MA-SC4) were selected in the present paper, 25cases of skin pruritus were treated by combination of the auricular acupuncture and routine method, andanother 25 cases were treated with the routine method as the control group. The result showed better therapeutic effect in the former than the latter with statistical difference.
6.Effect of CT-aided Scalp Surrounding Needling on Infarction Dementia by Retaining Long Time
Lei LIU ; Xin LUN ; Yifeng WANG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(6):569-571
Objective To observe the effect of CT-aided scalp surrounding needling on infraction dementia by retaining long time. Methods 53 infraction patients following dementia were randomly divided into treatment group (n=26) and control group (n=27). The control group was treated with CT-aided scalp surrounding needling for 30 minutes, while the treatment group was treated with CT-aided scalp surrounding needling for 3 hours. The course was 8 weeks. The therapeutic effect was assessed by Mini-Mental State Examination(MMSE), Hasegawa Dementia Scale(HDS-R) and Activities of Daily Living (ADL). Results The scores of ADL, MMSE, and HDS-R improved obviously after treatment in two groups (P<0.05), and the treatment group was better than the control group (P<0.05). Conclusion CT-aided scalp surrounding needling by retaining long time may facilitate to enhance the clinical effect on infarction dementia.
7.Courses Design of the New Subject Meridian and Acupuncture
Xin LUN ; Suhe LI ; Xinfang HE ; Guohua LIN ; Junjun YANG
Chinese Journal of Medical Education Research 2003;0(04):-
We began our teaching reform by following the step of national adjustment of majors frame at the end of last century.We perfected our teaching contingent,created advanced content, composed high quality text book,used multiple teaching methods and ways, paid attention to practical teaching,carried out effective access system and in the end,we firstly combined Meridian and Collateral and Acupuncture,which are the two major courses,into one basic course called Meridian and Acupoint.It covers different levels of students including doctors,postgraduates,undergraduates and seven-year-class students and has the features of abundant and detailed content,creative methods and excellent effects.
8.Clinical Observation of Vascular Dementia Treated by Surrounding-acupuncture of the CT-located Area
Xin LUN ; Bifang FENG ; Li RONG ; Wenhui YANG
Journal of Acupuncture and Tuina Science 2003;1(1):20-21
Purpose To observe the clinical effect of Surrounding Needling Technigue through CT Location in treating vascular dementia. Method Fifty cases of vascular dementia were randomly divided into surrounding Needling Technigue through CT location and routine acupuncture groups, 25 cases in each group,and were given surrounding Needling Technigue through CT location and routine acupuncture respectively. Results The effective rates in surrounding Needling Technigue through CT location and routine acupuncture groups were 88% and 60% respectively, and there was significant difference between the two groups, P < 0.01.Conclusion Therapeutic effect of surrounding Needling Technigue through CT location in treating vascular dementia was satisfactory, and better than that of routine acupuncture.
9.The expression of glutamate receptor in hippocampus of neonatal rats with hypoxic-ischemic brain damage
Xiaojuan TANG ; Bin SUN ; Ying WANG ; Xin DING ; Lun YU ; Lixiao XU ; Xing FENG
Journal of Clinical Pediatrics 2014;(4):368-371
Objective To study the expression of Ca-A/K channel-related molecules glutamate receptor 2 and 1(GluR2/1) in hippocampus tissues of neonatal rats with hypoxic-ischemic brain damage (HIBD). Methods A total of 60 7-day-old Sprague-Dawley rats were randomly divided into sham operation group and HIBD group. Hippocampal tissues were obtained at 0 h, 1 h, 6 h, 24 h, 48 h and 72 h after HIBD. The expression of GluR2, GluR1 and autophagy marker protein Beclin-1, LC3 were detected by Western blot assay. Results Edema and focal softening and necrosis were observed 6 h after HIBD in the brains of neonatal rats. Compared with Con group, at each time point, the expression levels of GluR2 were lower while the levels of GluR1, Beclin-1 and LC3 were higher significantly in HIBD group (P<0.05). The protein levels of LC3, Beclin-1, GluR1 and GluR2 in hippocampus tissues of HIBD group were significantly different among different time points after the estab-lishment of HIBD model (F=10.65~701.14, P<0.01). The protein level of GluR2 was decreased from 1 h to 24 h after HIBD and reached the lowest level at 24 h. The levels of GluR1, Beclin-1 and LC3 were increased at 6 h, plateaued at 24 h and remained there until 48 h. The levels of these proteins returned back to the initial level at 72 h. Conclusions Ca-A/K channel-related mol-ecules GluR2 and GluR1 play important roles in the autophagic cell death of hippocampus tissues in neonatal rats with hypoxic-ischemic brain damage.
10.Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma: report of a case.
Jin-fan LI ; Qin YE ; Bo HONG ; Xin GAO ; Kan-lun XU
Chinese Journal of Pathology 2011;40(9):638-639
Adenocarcinoma, Papillary
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metabolism
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pathology
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secondary
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surgery
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Adult
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Diagnosis, Differential
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Female
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Follow-Up Studies
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Humans
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Keratin-7
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metabolism
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Keratins
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metabolism
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Lung Neoplasms
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metabolism
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pathology
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secondary
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Nasopharyngeal Neoplasms
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metabolism
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pathology
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surgery
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Nuclear Proteins
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metabolism
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Thyroid Neoplasms
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metabolism
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pathology
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secondary
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Thyroid Nuclear Factor 1
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Transcription Factors
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metabolism