1.The Revision of Children's Perception of Marital Conflict Scale
Chinese Mental Health Journal 2002;0(08):-
Objective:To revise the children's perception of interparental conflict scale (CPIC) developed by Grych and his colleagues and examine its reliability and validity Method:Data were collected from a sample of 303 primary school students tested with the CPIC scale Results:The results of factor analysis and hierarchical cluster analysis showed that the revised CPIC had a good construct validity; and ?coefficient of the whole scale is 0 879, the reliability coefficient of split-half is 0 865, and the ?coefficient of each dimension was more than 0 657 Conclusion:The CPIC scale is suitable for Chinese children after revision
2.Intraoperative vessel thrombosis and its management in free flap transfers in head and neck region.
Chi MAO ; Guang-Yan YU ; Xin PENG
Chinese Journal of Stomatology 2009;44(5):304-305
Adolescent
;
Adult
;
Aged
;
Aged, 80 and over
;
Blood Vessels
;
injuries
;
Child
;
Child, Preschool
;
Female
;
Free Tissue Flaps
;
blood supply
;
Head
;
surgery
;
Humans
;
Male
;
Middle Aged
;
Neck
;
surgery
;
Tissue Transplantation
;
adverse effects
;
methods
;
Young Adult
3.Treatment of pediatric radial neck fractures with elastic intramedullary nail:a report of 16 patients
Xin LIU ; Leiting CHI ; Zhiqiang DENG
Chinese Journal of Trauma 2011;27(6):534-536
Objective To discuss the clinical effect of titanium elastic intrameduUary nail (TEIN)in treatment of pediatric radial neck fractures. Methods A total of 16 children with radial neck fractures were treated TEIN from February 2008 to February 2010.Long arm cast immobilization was used one week postoperatively and functional exercise was done after removal of the external fixation.Results All the patients were followed up for average 5.3 months (3.5-14.0 months),which showed the average period of bony union for 5.8 weeks(4-7 weeks).Except for one patient who aroused skin soft-tissue irritation symptoms at the nail end,no other complication was found.The range of motion of the elbow and forearm in injury side of all patients Was the same as the normal side. Conclusions The application of TEIN has advantages of minimal invasive lesion,nil effect on pheseal plate,good fracture union,rapid functional rehabilitation and little compliations and hence is one of ideal choices in treatment of pediatric radial neck fracture.
4.Revision and Application of the Social Support Appraisal Scale
Ziqiang XIN ; Liping CHI ; Liuna GENG
Chinese Mental Health Journal 1988;0(06):-
Objective: Exploring the reliability and validity of Chinese version of The Social Support Appraisal (SS-A) scale developed by Vaux et al (1986) and the characteristics of adolescent's social support.Methods:Using the scale, 515 junior and senior high school students were investigated.Results:(1) The SS-A scale had internal consistency of 0.91 for the scale and of 0.81-0.84 for three dimensions and a three-factor model was supported by the data (?2/df
5.Effect of Air Formaldehyde Exposure of Medical Students on DNA-Protein Crosslinks in Their Buccal Mucosa Cells
Jin YAN ; Yingshuai LIU ; Xin CHI
Journal of Environment and Health 1989;0(06):-
Objective To study the effect of formaldehyde exposure on DNA-protein crosslinks (DPC) in buccal mucosa cells in students who were taking anatomy course.Methods The modified SDS-KCl precipitation assay published by Zhitkovich and Costa in 1992 was applied to detect DNA-protein crosslinks in human cells.And this method has been used to explore DPC induced by different pollutants in numerous studies.37 medical students (20 males and 17 females) aged 19.24?1.09 (mean?standard deviation) and 40 students (20 males and 20 females) in natural science college aged 19.55?0.99 (mean?standard deviation) were studied.The frequency of exposure to formaldehyde was 6 h per week in exposed group.Results Concentrations of formaldehyde in anatomy laboratory ranged from 0.42 to 1.57 mg/m3.Exposure to formaldehyde resulted in an increase of DNA-protein crosslinks.The percentage (mean?standard deviation) of DNA-protein crosslinks in exposed and nonexposed students were 25.72%?6.48% and 22.88%?5.34% respectively(P0.05).Conclusion The result of the present study suggests that formaldehyde exposure in medical students increases the frequency of DNA-protein crosslinks in buccal mucosa cells and females may be more sensitive to formaldehyde exposure.
6.Free submental flap for defects reconstruction after oral cancer ablation
Chinese Journal of Microsurgery 2015;38(1):8-11
Objective To investigate the clinical application of free submental flap for defects reconstruction after oral cancer ablation.Methods Eleven cases of free submental flaps for defects reconstruction after oral cancer ablation from April,2013 to May,2014 were reviewed.The primary disease,defect type,flap side,flap size and flap survival rate were recorded.The follow-up data of tumor recurrence,lymph node metastasis,as well as postoperative facial appearance and function of marginal mandibular branch of facial nerve were collected.Results Primary disease of all 11 cases was oral squamous cell carcinoma.No flap failure was reported and the overall flap survived.The follow-up period was 6-18 months with the average of 9 months.There was no tumor recurrence and metastasis of lymph node.Postoperative facial appearance was satisfactory and there was no nerve injury of marginal mandibular branch which showed normal and symmetrical expression motion.Conclusion Free submental flap owns many ad vantages including constant anatomy,long vascular pedicle,wide range of indications and low donor-site morbidity.Contralater submental flap may avoid potential lymph node metastasis.Free submentai flaps is an ideal choice for reconstruction of oral and maxillofacial defects after cancer ablation.
7.Combined free fibula flap and radial forearm flap in the reconstruction of extensive composite oro-mandibular defects
Chi MAO ; Guanyan YU ; Xin PENG
Journal of Practical Stomatology 2000;0(05):-
Objective: To analyze the value and reliability of combined free fibula flap and radial forearm flap in the reconstruction of extensive composite oro-mandibular defects. Methods: Extensive composite oro-mandibular defects were reconstructed in 23 consecutive cases (averagely aged 52.9 years old) with combined free fibula flap and radial forearm flap from March 2000 to January 2002. Data concerning the operation, defect description and site, recipient vessel and complications were reviewed. Results: The overall flap survival rate was 100% (all of 46 flaps) without partial or total flap necrosis. The overall complication rate was 30.4%. The vessel thrombosis rate was 2.2%, and the flap salvage rate was 100%. Conclusion: In selected cases, combined free fibula flap and radial forearm flap method may provide satisfactory reconstruction for extensive oro-mandibular defect, and greatly improve the quality of life of patients.
9.The effectiveness and reliability of skin paddles of free fibula flaps in reconstruction of maxillofacial defects.
Chi MAO ; Xin PENG ; Guangyan YU
West China Journal of Stomatology 2002;20(1):30-32
OBJECTIVEThe paper reviewed the effectiveness and reliability of skin paddles of free fibula flaps in the reconstruction of maxillofacial defects.
METHODSFifty-five consecutive free fibula osteocutaneous flap transfers performed from June 21, 1999 to October 31, 2000 were reviewed. The skin paddles of each flap were analyzed in terms of surgical design, blood supply, size, reconstruction location, and survival.
RESULTSFifty-seven skin paddles were used for the 55 free fibula flaps (double skin paddles for 2 flaps), 37 were nurtured by one perforator, 18 by two and two by 3 perforators. Twenty-eight skin paddles were used for intraoral reconstruction, 7 for extraoral reconstruction, 1 for both intraoral and extraoral reconstruction, 2 for soft tissue augmentation, and the remaining 19 were simply used as window for monitoring the blood flow of fibula flap. One free fibula flap with one skin paddle was lost because of venous thrombosis, and the other 54 flaps survived completely, with 100% survival of 56 skin paddles.
CONCLUSIONThe skin paddle of free fibula flap is safe and reliable. It can be used for all kinds of soft tissue reconstruction, as well as window for monitoring the blood flow of fibula flap after operation.
Adolescent ; Adult ; Aged ; Child ; Female ; Fibula ; Humans ; Male ; Mandible ; surgery ; Mandibular Neoplasms ; pathology ; surgery ; Microsurgery ; Middle Aged ; Mouth Neoplasms ; pathology ; surgery ; Oral Surgical Procedures ; methods ; Postoperative Complications ; surgery ; Reconstructive Surgical Procedures ; methods ; Reoperation ; Skin Transplantation ; Surgical Flaps ; blood supply ; Tissue and Organ Harvesting ; methods
10.The long non-coding RNA HOTTIP promotes the proliferation of non-small cell lung cancer cells through the regulation of apoptosis
Fachen ZHOU ; Lei ZHAO ; Yuxin BAI ; Xinming CHI ; Xin ZHOU
China Oncology 2015;(9):652-658
Background and purpose:Exploration of the effective early diagnostic and prognostic markers of non-small cell lung cancer (NSCLC) has important scientiifc signiifcance and clinical value. Recently, the role of long chain non-coding RNA (lncRNA) in the tumor attracts widespread attention. This study intended to investigate the level of lncRNA HOTTIP in NSCLC, the effect of HOTTIP on cell proliferation and its mechanisms.Methods:Expression of lncRNA HOTTIP in tumor and their matched non-tumor tissues were determined by quantitative real-time PCR (qRT-PCR) in NSCLC patients. Then, we analyzed the potential correlation of lncRNA HOTTIP expression levels in tumor tissues with clinicopathological features of NSCLC and clinical outcome. The effects of HOTTIP on NSCLC cell proliferation and apoptosis were tested usingin vitro MTT and lfow cytometric assays. Western blot method was uesd to detect the expressions of proteins.Results:LncRNA HOTTIP expression level was signiifcantly decreased in NSCLC tissues in comparison to adjacent non-tumor tissues (P<0.05). It was also proved that HOTTIP expression was associat-ed with NSCLC histological grade and lymph node metastasis. Moreover, knockdown of HOTTIP expression in A549 cell line decreased proliferation and enhanced apoptosis compared with transfected negative control. Western blot assay showed that the level of Bax protein was signiifcantly increased, whereas Bcl-2 was signiifcantly decreased in HOT-TIP-silencing A549 cell.Conclusion:HOTTIP is a novel prognostic biomarker and a potential therapeutic candidate forNSCLC.