Objective To explore the clinical effect of Huazhuo Tongqing Yin in treating chronic atrophic gastritis (CAG) with internal accumulation of turbidity and poison. Methods A total of 159 patients with CAG were randomly divided into traditional Chinese medicine group, western medicine group and control group, and were given Huazhuo Tongqing Decoction, rabeprazole sodium enteric-coated tablets and morodan, respectively. Clinical efficacy, TCM syndromes, pathological changes, 36-item Short-form Health Status Survey(SF-36) score and serum gastrin-17 (G-17) and prostaglandin E₂ (PGE2) before and after treatment were compared. Results The total effective rate was 92.45% in Chinese medicine group, 62.26% in western medicine group and 66.04% in control group. After three months of treatment, the scores of epigastric pain, gastric distension and discomfort, acid regurgitation and heartburn, belching, and stool stickiness in the three groups were all lower than those before treatment, and the scores of epigastric pain, gastric distension and discomfort, acid regurgitation and heartburn, belching, and sticky stool in the traditional Chinese medicine group were lower than those in the control group andthe western medicine group (P < 0.05). The SF-36 scores of the three groups at 1-, 2-, 3-month improved after treatment, and the SF-36 score of the traditional Chinese medicine group was higher than that of the control group and the western medicine group (P < 0.05). During follow-up, the SF-36 score of the traditional Chinese medicine group was still higher than those of the control group and the western medicine group (P < 0.05). After treatment, the serum levels of G-17 and PGE2 in the three groups were higher thanthose before treatment, and were higher in the traditional Chinese medicine group than those in the western medicine group and the control group (P < 0.05). No adverse reactions occurred in any of the three groups during treatment. Conclusion Huazhuo Tongqing Decoction can alleviate the symptoms of CAG, improve the pathological state and the quality of life.

Objective:To analyze the research status of ground-level ozone pollution, explore research trends and hot spots, and provide references for future research on air pollution.Methods:Papers on ground-level ozone pollution research published before December 31, 2019 had been retrieved in SCI-E database of the "Web of Science Core Collection" in January 2020. The retrieval strategies were set as follows: TS= ( ("Tropospheric Ozone" OR "Low Level Ozone" OR "Ground Level Ozone") AND ("Air pollution*" OR "Air quality") ) . The survey included 2084 articles. By using bibliometric research and visual analysis tools, the research status of global ground-level ozone pollution was revealed from the aspects of time, discipline, journal, financing, institution, country and key words.Results:Cumulative publications increased in a cubic function of y=0.05 x3+0.80 x2+0.74 x+4.55 ( R2=0.999, P<0.01) . The most studied subject was Environmental sciences ecology (1401 articles, 67.23%) . Atmospheric Environment was the journal with the most articles (332 articles, 15.93%) . The United States was the country with the most publications (44.67%, 931/2084) , while China ranked second (17.13%, 357/2084) . 80.39% (287/357) of Chinese papers had funding information. Among the top 10 research institutions, 7 and 2 were affiliated to the United States and China respectively. Source apportionment and human health were high frequency keywords that had appeared in the last 5 years. Conclusion:The research on ground-level ozone pollution is in a good period of development. The United States has a leading position in this area, and China has a good prospect in this field. Pollution source apportionment and human health effects are new research directions.

Objective:To analyze the research status of ground-level ozone pollution, explore research trends and hot spots, and provide references for future research on air pollution.Methods:Papers on ground-level ozone pollution research published before December 31, 2019 had been retrieved in SCI-E database of the "Web of Science Core Collection" in January 2020. The retrieval strategies were set as follows: TS= ( ("Tropospheric Ozone" OR "Low Level Ozone" OR "Ground Level Ozone") AND ("Air pollution*" OR "Air quality") ) . The survey included 2084 articles. By using bibliometric research and visual analysis tools, the research status of global ground-level ozone pollution was revealed from the aspects of time, discipline, journal, financing, institution, country and key words.Results:Cumulative publications increased in a cubic function of y=0.05 x3+0.80 x2+0.74 x+4.55 ( R2=0.999, P<0.01) . The most studied subject was Environmental sciences ecology (1401 articles, 67.23%) . Atmospheric Environment was the journal with the most articles (332 articles, 15.93%) . The United States was the country with the most publications (44.67%, 931/2084) , while China ranked second (17.13%, 357/2084) . 80.39% (287/357) of Chinese papers had funding information. Among the top 10 research institutions, 7 and 2 were affiliated to the United States and China respectively. Source apportionment and human health were high frequency keywords that had appeared in the last 5 years. Conclusion:The research on ground-level ozone pollution is in a good period of development. The United States has a leading position in this area, and China has a good prospect in this field. Pollution source apportionment and human health effects are new research directions.