Objective To observe the therapeutic effect of Lanqin oral liquid on the wind heat syndrome of the fever caused by viral upper respiratory tract infection.Methods 130 cases from our hospital of the fever(wind heat syndrome)caused by viral upper respiratory tract infection,including 20 confirmed cases of H1N1 influenza A,8 suspected cases,and 41 clinically diagnosed cases were treated with Lanqin oral liquid,for 3 days'treatment and oneday follow-up,the rate of instant antipyretic effect and the antipyretic time were observed.Results The fever was reduced in 39 cases(30.0％)and 118 cases(90.8％),within 4h and 72h after medication respectively.The average antipyretic time was 20.5h.Conclusion Lanqin oral liquid can treat the fever(wind heat syndrome)caused by viral upper respiratory tract infection effectively.

Objective To discuss the diagnostic value of detecting plasma vitamin B12 and Homocysteine (Hcy) in subacute combined degeneration of the spinal cord (SCD).Methods Parents of SCD (n=29) and subjects (n=74) without spinal cord diseases were enrolled from the clinic of Shaanxi Provincial People's Hospital from April 2014 to July 2016.The plasma vitamin B12 and Hcy concentrations were detected using Chemiluminescence Immunoassay (CLIA) and enzyme-linked immuno sorbent assay (ELISA) respectively,and compared using chi-square between the SCD and control groups.Sensitivity rate,specific rate,and diagnose accordance rate were evaluated.Results The plasma homocysteine and vitamin B12 concentrations in SCD and control groups were 49.41 μmol/L vs 12.36 μmol/L,44.35 pg/ml vs 166.75 pg/ml,with significant differences (U=343.50,800.00,P＜0.05).Negative correlation existed between the concentrations of vitamin B12 and Hey (r=-0.248,P=0.012).The sensitivity rates of vitamin B12 and Hcy detections were 55.2％ vs 89.7％,which had significant differences (x2 =8.631,P=0.003),and the diagnose accordance rate (69.9％ vs 64.1％) of the former was higher (x2 =4.175,P=0.041).Conclusion The plasma Hcy and vitamin B12 concentration detections had definite diagnostic value in SCD,and Hcy had higher sensitive rate,which can improve the diagnostic rate of SCD in the early stage.

With the deeper understanding of tumor , more and more evidence indicates that the occurrence and development of tumors are closely related to the body′s immune function .More and more researches focus on tumor immunology to find an effective way of enhancing anti-tumor immunity . Radiotherapy has played an important role in anti-tumor immunity recently though it was believed as a traditional treatment for cancer before .Radiotherapy could convert a cold tumor into a hot tumor, which might ameliorate immune suppressive microenvironment , improve tumor immunogenicity and activate the cellular immune response .However, the abscopal effectof single radiotherapy is very rare . Immunotherapy is capable of enhancing the immune response produced by radiotherapy .In this paper , the basic theory and clinical practice of radiotherapy and immunotherapy were reviewed and the related clinical strategies were summarized .

Objective To study the clinical significance of hypersensitive C‐reactive protein(hs‐CRP) in acute coronary syndrome (ACS) .Methods 45 patients with ACS were selected as the ACS group ,including 26 cases of acute myocardial infarction (AMI group) and 19 cases of unstable angina pectoris (UAP group) ;30 patients with stable angina pectoris(SAP) were selected as the SAP group and 30 health people with healthy physical examination in the outpatient department as the control group .The latex‐en‐hanced immunoturbidimetry was adopted to detect the serum hs‐CRP levels in all selected subjects and the detection results were compared .Results The serum hs‐CRP level of ACS and SAP groups were significantly higher than that of the control group with statistical difference (P< 0 .01) .The hs‐CRP level of AMI and UAP groups was higher than that of the SAP group with statistical difference (P< 0 .05) .Conclusion hs‐CRP is an independent risk factor for ACS and one of the most powerful predictors ,able to quickly and accurately conduct early diagnosis ,risk stratification ,condition monitoring and prognosis judgment in the patients with ACS .

Theoretical studies of detection system of human body functions reflecting characteristics of Chinese medicine show that the three indicators of intake of the body from outside and the digestion and absorption of supply perunit time to ensure maximum quality,the energy consumed to maintain the five internal organs function perunit time and the dissipation of body storage perunit time will be able to fully reflect the changes in physiological and pathological status.Based on this theory,data obtained from the new understanding of the classification of the clinical symptoms in the characteristics of life as well as traditional Chinese medicine(TCM) symptoms,TCM symptoms unit and clinical symptoms attribute to TCM symptom information instrument detection.The human body function tests will be an extension of the TCM diagnostic methods,which will supplement the content of clinical symptoms and is expected to become a TCM therapeutic evaluation of quantitative detection methods.

Objective To investigate the relationship between the the expression of SOCS-1/3 in the peripheral blood mononuclear cells (PBMCs) and interferon therapeutic response in patients with chronic hepatitis B.Methods 50 patients with chronic hepatitis B were given interferon therapy.After 24 weeks treatment,according to biochemical and virologic response,they were divided into two groups:response and non response group.HBV-DNA was detected by PCR.The SOCS-1/3 mRNA levels were measured by RT-PCR.Results The expression of SOCS-1 in the PBMCs of response group after 24 weeks treatment was significantly higher than that before interferon therapy (P ＜ 0.05).The expression of SOCS-3 in the PBMCs of response group after 24 weeks trentment was significantly lower than that before interferon therapy (P ＜ 0.05).In non response group,there were no significant differences in the expression of SOCS-1/3 (P ＞ 0.05).Conclusion The increase expression of SOCS-1 mRNA and the decrease of SOCS-3 mRNA in the PBMCs in chronic hepatitis B patients received 24 weeks interferon-therapy probably is relevant to the IFN-α antiviral effect.

This article was aimed to propose and develop traditional Chinese medicine (TCM) health engineering, using modern science and technology, in order to carry out the detection research which reflected TCM features of human functional state. It was an important way to achieve TCM diagnosis and the objective evaluation on therapeutic effects of TCM. The combination of TCM health engineering with information technology, and the formation of TCM functional state intelligent identification system, as well as the extension into the Health Internet of Things (HIT) could provide more accurate and convenient services for human healthcare in the age of big health. And identification on TCM syndromes was the core to achieve this goal. Using characterization data on TCM syndromes could realize the data processing between TCM syndrome and prescription through intelligent computing, in order to form the TCM syndrome differentiation and treatment intelligent system. It had great significance in the promotion of TCM health project.

Based on the theory of topological structure within the syndrome of tradition Chinese medicine (TCM), the high order multiple dimensions and nonlinear structure of syndrome can be cracked. And the panorama of complex and changeable syndrome can be showed. The dynamic evolving law of sub-sets of syndromes and the changing rule of the main signs and symptoms with the secondary signs and symptoms can be interpreted. Therefore, the evolving law of sub-sets of syndromes and the accurate corresponding law of prescriptions and medicines can be realized. And the scientific connotation of dynamic evolving rule of syndrome can be revealed. Studying on the occurrence regularity of syndrome, the structure characterization of TCM syndrome can be carried out. And the mathematical structure-physical structure-biological structure can be revealed. Along with the mass new specific forms of syn-dromes to be cracked, the simulation data platform of therapeutic methods with prescriptions and medicines of syn-dromes can be built through the simulation technology of computer. Using the clinical data, through the literature of carding and contrast, the scientific connotation of judgment and diagnostic standard of syndromes can be interpreted. The distracting law of syndromes of diseases can also be revealed through the clinical data of syndrome-groups. And the theoretical basis for the formulation of judgments and diagnostic standard of syndromes of diseases which con-forming to the dynamic evolving law of syndromes can be provided. Evaluation on TCM efficacy can be carried, in order to make clear the curative effect evaluation index system of TCM syndrome in multiple dimensions and multi-ple levels for the promotion of the substantially improvement of syndrome differentiation level.

Objective The purpose of this study was to discuss the effect of visible light therapeutic equipment accompanied with electrolyzed-oxiding water (EOW) on pressure ulcer above the second phase. Methods We divided 44 patients with pressure ulcer above the second phase into the test group (23 cases, 28 spots) and the control group (21 cases, 25 spots). The test group received local decompression, debridement with EOW, exposure to visible light for 20 minutes, 10 times per day. The control group adopted local decompression, debridement with normal saline and local application of burn cream, 3 times per day. Results The effective rate of the test group was apparently higher than that of the control group (P<0.05). The healing time was also shorter than that of the control group (P<0.01). Conclusion Treatment of pressure ulcer above the second phase with visible light therapeutic equipment accompanied with electrolyzed-oxiding water proved to be an effective treatment method.

OBJECTIVE To investigate pathogenic bacteria isolated from children with respiratory tract infection(RTI) and bacterial resistance to commonly used antimicrobial agents in Guilin area,so as to instruct the rational use of antibiotics.METHODS Routine methods were used to isolate and identify bacteria species and samples of sputum or throat swabs were collected from children with respiratory infection in inpatient departments.The drug susceptibility tests were performed by Kirby-Bauer method.RESULTS Total 733 strains of bacteria were isolated.The Haemophilus influenzae(HI) was the most common(165 strains),followed by Escherichia coli(136 strains) and Streptococcus pyogenes(51 strains).The resistance of HI to trimetoprim-sulfa methoxazole and ampicillin was 59.39% and 36.36%,respectively.Cephalosporins and quinolones were more sensitive to HI.Imipenem,quinolones and amikacin were more sensitive to E.coli as yet.The resistant rate of Streptococcus to penicillin-G,erythromycin,clindamycin and trimetoprim-sulfa methoxazole was 56.79-69.63%.CONCLUSIONS Gram-negative bacilli are the main pathogenic bacteria in childrens respiratory tract infection.The drug resistance is conspicuous.Antibiotics for treating RTI should be selected based on pathogenic bacteria variance and the drug susceptibility test.