1.Innovative application of medical internet based on the construction of single wireless web platform
Wen ZHANG ; Xikun MA ; Jingjie YU
Journal of Medical Postgraduates 2015;(8):850-852
The construction of single wireless web platform is an important condition for the development of clinical informa -tion technology .The aim of this study was to explore the construction of wireless web platform in hospital and innovative applications of medical internet based on this platform .The medical internet was applied innovatively through the construction of multi -service wireless web platform .Based on the innovative application of medical networks such as cold chain system and transfusion monitoring system , special clinical requirements were fulfilled so as to improve medical safety and medical quality .The multi-service wireless web platform can realize the integration of multi-networks and multi-systems to avoid overlapping investment and redundant construction in hospital .
2.Organization and implementation of VLAN division in hospital
Xikun MA ; Xudong XU ; Anbin LIU
Chinese Medical Equipment Journal 1989;0(04):-
This paper introduces the overall strategy of routing,the organization and preparation as well as the implementation of VLAN division in Nanjing General Hospital of Nanjing Military Region.VLAN can control the broadcast storm and enhance the safety and management of local area network.
3.Combination of endoscopic submucosal dissection and endoscopic band ligation in treatment of upper gastrointestinal submucosal tumors
Fubing YU ; Xikun HE ; Bing ZHANG ; Zan ZUO ; Tianle MA
Chinese Journal of Digestive Endoscopy 2009;26(9):455-459
is able to provide pathologic data and achieve the efficacy equivalent to surgery.
4.Research and application of information system for emergency doctor workstation
Xikun MA ; Guobin YANG ; Xudong XU ; Zhong WANG
Chinese Medical Equipment Journal 2004;0(08):-
The thesis introduces the experience of research and application of the information system for emergency doctor workstation.The system consists of the section of patient selection and switch,patient listing,medical records and the maintenance.The application of the system helps the optimization of the work process,the safety drug-taking,the normalization of medical documents,and the share of the medical resources.
5.Application of telemedical consultation to the emergency treatment of the wounded from Wenchuan Earthquake
Shuguang ZHANG ; Lijun ZHOU ; Bing YAO ; Liping ZHANG ; Xikun MA
Journal of Medical Postgraduates 2003;0(08):-
By applying the satellite-based distance rescue system and telemedical technology to the emergency treatment of the wounded from the Wenchuan Earthquake,we successfully conducted joint telemedical consultations with the guidance of the top specialists from various distant areas and saved 3 critically wounded patients.Our experience has shown that telemedical consultations may give a full play to the functions of large rescue organizations and the abilities of the top specialists,improve the treatment and expand war-time medical support.
6.Practice of Improving Quarter Inspection Tour Benefit of Computer Repair and Maintenance Outsourcing Service
Xudong XU ; Xikun MA ; Haojie WEN ; Zhiping WANG ; Xiaoyan ZHANG ; Bin SU
Chinese Medical Equipment Journal 1989;0(01):-
To introduce the method, content and the benefit of constituting inspection tour quality bulletin system and as- sessing the inspection tour computer capability grade of the quarter inspection tour of computer repair and maintenance outsourcing service. By improving the computer routine inspection tour in practice, we can enhance the integrated benefit of the computer quarter inspection tour. As an effective approach of the network equipment preventive repair and mainte- nance, after the computer quarter inspection tour system was optimized and improved, it got the end-users and hospital or- ganization' high attention and full affirmation for the good integrated benefit.
7.Design and Implementation of Disaster Recovery Scheme for Hospital Information System
Min HU ; Xudong XU ; Shuguang ZHANG ; Yanjun WU ; Xikun MA ; Zhiping WANG
Chinese Medical Equipment Journal 2003;0(11):-
Objective To design a disaster recovery scheme for hospital information system. Methods The data disaster recovery and applied disaster recovery for hospital information system are realized by using the redundancy backup technology, active -standby technology, cluster technology and load balance technology. Results The continuity of the business is assured. Conclusion The reliability and the usability are increased.
8.Pharmacokinetic profiles of antifungal drugs during extracorporeal membrane oxygenation life support
Dengyun FAN ; Shan LI ; Yixin LIU ; Feifei REN ; Zhenzhen YANG ; Xikun WU ; Yingchao MA ; Zhiqing ZHANG ; Yakun ZHANG
Chinese Critical Care Medicine 2022;34(1):100-104
Extracorporeal membrane oxygenation (ECMO), a kind of life support technology that can replace lung and heart function, is widely used in critical respiratory and circulatory exhaustion. Because of the serious diseases and the use of interventional catheters, patients receiving ECMO life support are often administrated with broad-spectrum antimicrobial agents, which increase the risk of fungal infection. Fungal infection during ECMO can increase mortality. How to effectively control fungal infection is a thorny problem faced by clinicians. During the treatment of ECMO, the patient's physiological status, ECMO oxygenation membrane, circulation pipeline and other factors may change the pharmacokinetic profiles of antifungal drugs, thereby affect the clinical efficacy of drugs. This artical reviews the pharmacokinetic characteristics of antifungal drugs during ECMO support, in order to provide references for clinical antifungal treatment.
9.Research progress in pharmacokinetics/pharmacodynamics and therapeutic drug monitoring of biapenem
Xinglong TAO ; Yu ZHANG ; Xikun WU ; Xiaosong MA ; Tiantian ZHANG ; Xia WU ; Weichong DONG ; Ning SONG ; Zhiqing ZHANG
China Pharmacy 2023;34(15):1915-1920
Biapenem is a carbapenem antibiotic, and can be used for the treatment of sepsis, pneumonia, lung abscess, chronic respiratory lesions secondary infection, complex urinary tract infection and pyelonephritis, etc. This article reviewed the studies on the pharmacokinetics, pharmacodynamics and therapeutic drug monitoring (TDM) of biapenem. The pharmacokinetic parameters of biapenem are not significantly different in healthy subjects, and there is no accumulation after multiple doses of biapenem. However, there are large differences in pharmacokinetic parameters in patients with severe disease and patients with abnormal renal function compared with healthy subjects, which leads to conventional treatment regimens not achieving the desired outcome. In terms of pharmacodynamics, biapenem can improve the rate of reaching the target value by increasing the frequency of administration and prolonging the infusion time. For patients with anuria in end-stage renal disease, dosing intervals can be extended to avoid drug accumulation. However, for patients with severe infection, a daily dose of 1.2 g still can not control infections caused by Acinetobacter baumannii or Pseudomonas aeruginosa, which limits its use in patients with severe disease. It is recommended to implement TDM in severe patients and patients with abnormal renal function, and explore the best dosing regimen for biapenem in combination with pharmacokinetic models to ensure that the time that the free blood concentration of biapenem remains above minimum inhibitory concentration as a percentage of the time between doses (%fT>MIC) is within the effective range,so that biapenem can exert a greater efficacy in severe patients and patients with abnormal renal function. For medical institutions that cannot carry out TDM, the efficacy of biapenem can be maximized by increasing the frequency of administration and prolonging the infusion time. For infections caused by P. aeruginosa, A. baumannii and Serratia marcescens with high drug resistance rates, it is recommended to combine or replace other antibiotics.