This investigation was to evaluate the implication of interventional therapy in postpartum hemorrhage at emergency settings. Due to the failure of conservative therapy, nineteen postpartum hemorrhage cases received digital subtraction angiography(DSA)followed by internal iliac or uterine artery embolization by using gelatin sponge. As a result, all of 19 patients showed good response to the treatment, and no recurrence Was found after 6 months' follow-up. Our findings suggested that artery embolization is a safe, effective and micro-invasive treatment strategy for intractable postpartum hemorrhage, which could reduce mortality and avoid hysterectomy as well.