ObjectiveTo observe the relationship between the mean platelet volume (MPV) and stent thrombosis(ST) in patients after percutaneous coronary interventional procedures (PCI),to determine a concise and high-risk indicator to predict thrombosis in the patients after PCI.MethodsTo determine the MPV from 229 patients after PCI.The patients with MPV significantly increased were sekected as the observation group,the patients with normal MPV were selected as the control group.The stsituation in the two groups of ST was observed.The values in the two grups were analyzed.ResultsThe ST rate of control group was 1.22％,which was lower than that of the observation group(6.15％ )( x2 =4.02,P ＜ 0.05 ).ConclusionThe value of MPV increased was a risk factor for patients with thrombosis after PCI.Taking effective and timely adjustment of antithrombotic treatment options had an important clinical significance to prevent ST occur in patients after PCI.

Objective To compare the traditional anterior transposition and anterior subcutaneous with blood supply of the ulnar nerve for the treatment of cubital tunnel syndrome.Methods Eighty cases with cubital tunnel syndrome were enrolled in the retrospective study from January 2009 to March 2013,40 cases (control group) were treated by traditional anterior transposition while the others (observation group) were treated by anterior subcutaneous with blood supply.According to the evaluation criteria of ulnar nerve,evaluated the function of patients and compared the scores of two groups and the improved rate of different level patients.Results The scores of two groups before surgery were (3.6 ± 0.4),(3.7 ± 0.5) scores,after surgery were (7.5 ± 0.9),(7.4 ± 0.6) scores respectively,there was significant difference between two groups before and after surgery (P ＜ 0.05),but there was no significant difference between two groups (P ＞0.05).The improved rate of observation group was 87.5％ (35/40),which was higher than that of control group [85.0％ (34/40)],but without statistical difference (P ＞ 0.05).In two groups the patients with middle scores showed no statistical significance in improved rate [90.0％ (27/30) vs.96.4％ (27/28)] (P ＞ 0.05).Two treatments showed a significant difference for the low scores patients 8/10 vs.7/12 (P ＜0.05).Conclusion Anterior subcutaneous with blood supply of the ulnar nerve is better than traditional anterior transposition for the gross cubital tunnel syndrome patients.

ObjectiveTo determine the dose of butorphanol at which 50％ and 95％ effective dose (ED50 and ED95) of patients inhibition uterine contraction pain on analgesic artificial abortion.Methods Twenty-six patients undergoing analgesic artificial abortion were sequentially given different doses butorphanol so that the ED50 and ED95 could be determined by up-and-down sequential test.Anesthetic depth was observed when giving propofol with 200 mg/min speed,uterine contraction pain at awaking immediately,10,20 min after awaleing.Data was analyzed by Probit regression analysis for calculating ED50 and ED95..ResultsButorphanol could restrain uterine contraction pain on analgesic artificial abortion and the ED50 was 246 μg with the 95％ confidence interval of 201 μg to 281 μg,the ED95 was 324 μg with the 95％ confidence interval of 287 μg to 548 μg.ConclusionED50 and ED95 value can be expected as a parameter to optimize analgesic artificial abortion.

After an evaluation system of intellectual property rights in tea industry was constructed according to the investigation of literature and networks , the development of intellectual property rights in tea industry of China from 2004 to 2013 was analyzed , which showed that although the comprehensive strength of intellectual property rights in tea industry of China has steadily increased , a number of problems still exist such as its copyright , trademark rights, geographical indications, intangible cultural heritage, and new plant strain rights.Further analysis of patent invention rights, practical patents, and outward appearance designs showed that the number of tea processing patent inventions is the largest with a stable patent right, followed by tea processing and tea sets, tea sets and tea pack-age.Suggestions were put forward for the development of intellectual property rights in tea industry of China.

Indicators for evaluation of Chinese medicine intellectual property rights evaluation system were selected interms of patent right, copyright, trademark right, geographical mark, protection of Chinese medicine, and intangible cultural heritage to construct a Chinese medicine intellectual property rights evaluation system which is consisted of 6 class A,15 class B and 18 class C indicators .Domestic data of Chinese medicine intellectual property rights were col-lected from 2004 to 2013,the weight of each evaluation indicator was determined using standard deviation method,and the evaluation system was studied according to the weighted TOPSIS method with its rationality and practicality validated.

AIM To establish a UV spectrophotometry for the determination of arsenic in Jiuji Xingjun Capsules. METHODS Arsenic was transformed into hydrogen arsenide,then silver diethyldithiocarbamate was reduced for colloid silver by hydrogen arsenide,its absorbance was determined at the wavelength of 507 nm. RESULTS The linearity range of curve was 0.5-4.5 ?g?mL -1 ( r =0.999 5, n =7),The average recovery was 100.11 % ( RSD =1.64 T《B》 % , n =15). CONCLUSION This method is rapid and accurate.

ObjectiveTo discuss the mechanism of promotion of gastrointestinal motility during multiple organ dysfunction syndrome ( MODS ) by Dachengqi decoction, by examining the expression of Bcl-2, Bax of mitochondrial pathway, and nuclear factor-κB (NF-κB) in smooth muscle of the small intestinal in rats.Methods According to the random number table, 100 healthy adult Wistar rats were divided into three groups: control group with 20 rats, model group with 40 rats, and Dachengqi decoction group with 40 rats. Rat model of MODS was reproduced by bacterial peritonitis induced by an injection of 1 mLEscherichia coli suspension (8×108 cfu/mL) into peritoneal cavity. The rats in control group were given 1 mL normal saline intraperitoneally. The rats in Dachengqi decoction group were given 10 mL/kg Dachengqi decoction by gavage, twice a day, before inoculation of the bacterial suspension. Twenty-four hours after modelling, rats in all groups were sacrificed by cervical vertebra luxation, and the upper small intestine was harvested to detect the protein expressions of Bcl-2, Bax, and NF-κB in smooth muscle tissue using immunohistochemical staining.Results In the control group, a large amount of Bcl-2 protein was expressed and it was distributed uniformly in small intestinal smooth muscle. On the other hand, a small amount of Bax and NF-κB protein was expressed, and they were also distributed uniformly. Compared with the control group, Bcl-2 protein was distributed only sparsely, and it was scattered in intestinal smooth muscle in blocks in the model group. The expression of Bcl-2 protein was obviously down-regulated [integral optical density (A) value: 7 115.3±1 797.2 vs. 22 085.5±4 892.2, P< 0.05], and this phenomenon was more prominent in circular muscle layer. Bax and NF-κB were densely distributed, and their expressions were upgraded obviously [Bax (A value): 33 802.6±5 778.0 vs. 7 984.4±1 804.5, NF-κB (A value): 2 465.9±664.8 vs. 1 572.6±256.0, bothP< 0.05]. This phenomenon was more outstanding in circular muscle layer. Compared with that of the model group, the expression of Bcl-2 protein was stronger obviously in intestinal smooth muscle in Dachengqi decoction group (A value: 12 458.6±2 491.1 vs. 7 115.3±1 797.2,P<0.05). The expressions of Bax and NF-κB were down-regulated obviously [Bax (A value): 12 529.2±2 018.5 vs. 33 802.6±5 778.0, NF-κB (A value): 1 843.1±373.6 vs. 2 465.9±664.8, bothP< 0.05], and the change was more obvious in circular muscle layer.Conclusions Dachengqi decoction may promote recovery of gastrointestinal motility through an increase of Bcl-2 expression in nuclear membrane, thus preventing translocation of Bax to mitochondrion, thereby reduces mitochondrial damage in MODS.

Objective To investigate onthe correlation between the seven single nucleotide polymorphisms and genesis of T2DM. Methods High‐resolution melting (HRM ) curve technology was used to detect thegenotype of the seven SNPs in 202 T2DM patients and 200 healthy volunteers. The relationship between susceptible gene polymorphism and T 2DM was analyzed. Results The frequency of five SNP loci rs8050136 ,rs13266634 ,rs7578597 ,rs864745 and rs7961581 showed significant differences between T2DM patients and controls ( P< 0.01 ). The OR of rs8050136 ,rs13266634 ,rs757859 and rs864745 was >1 ,while OR of rs7961581 was <1. There was no significant difference in rs10811661 and rs10923931 loci between T2DM patients and controls (OR=1). Conclusion The polymorphism of loci rs8050136 ,rs13266634 ,rs7578597 and rs864745 is associated with T2DM genesis in this study population , while rs10811661 and rs10923931 is not associated with T 2DM genesis ,and rs7961581 may be a protective factor for T2DM.

BACKGROUND: Conservative treatment receives poor results in treating humeral intercondylar fractures,due to the over-long time fixation,and the recovery of joint function would be restricted.Early functional exercises should be based on stable internal fixation.OBJECTIVE: To explore the effectiveness of bone plate internal fixation in treating humeral intercondylar fractures under AO principle.METHODS: Totally 37 cases with humeral intercondylar fractures at the Department of Orthopaedics,Laibin People's Hospital from June 2000 to November 2005 were collected,under AO/ASIF classification,cases were assigned into three groups: type C1consisted of 11 cases,C2 consisted of 21 cases and C3 comprised 5 cases.All the cases were treated by olecranon osteotomy medial approach open reduction and then treated with dual anatomical plate internal fixation.Flexion and extension activities were done at 1 day after operation.Physical therapy was performed at 1 day after removing drainage.According to the images and clinical follow-up,slightly resistance exercise could be done at 4 weeks after operation,and gradually increased the load after8-12 weeks.RESULTS AND CONCLUSIONS: A total of 36 patients were included in the follow-up with 13-26 months,mean 19.5 months.All the bone fractures were recovered.Earlier operative reduction and exercise function would got better elbow joint recovery.All results demonstrated that dual anatomical plate treatment under AO principle provides firm internal fixation for patients with humeral intercondylar fractures,which is good for early exercise and functional recovery.

Objective To assess the diagnostic and preoperative classification value of MSCT after administration of water orally and meglumine diatrizoate enema in diagnosis of colonic neoplasms.Methods The day before examination,40 patients with colon carcinoma had a liquid diet and rountine clean enema,then underwent MSCT scan after administration of water orally and 2% meglumine diatrizoate enema.CT findings were analysed in comparison with postoperative pathologic features.Results There were 2 cases of rectal neoplasms,7 cases of sigmoid colon,6 cases of descending colon,5 cases of transeverse colon,and 20 cases of ascending colon cancer.According to Dukes' staging way,the lesions were B stage in 22 cases,C stage in 12 cases and D stage in 6 cases,the rate corresponding to operation was 89.6%.Conclusion MSCT scan after administration of water orally and 2% meglumine diatrizoate enema in diagnosis of colonic neoplasms has great value.