1.Endovenous laser treatment for venous ulcer of lower extremities
Zhaolei CHEN ; Xicheng ZHANG ; Yuan SUN ; Daorong WANG
International Journal of Surgery 2011;38(10):679-681
Objective To explore the value of endovenous laser treatment (EVLT) in treating the variceal ulcer of lower extremities (VULE).Methods Twenty cases of chronic venous insufficiency with VULE were treated with endovenous laser and received regular postoperative follow-up survey.Results No complication,such as burning of skin happened,all superficial varicose veins disappeared,and most of ulcers were healed within 2 -4 weeks after EVLT.Conclusion EVLT is one of the important methods which is minimally invasive and safe to treat VULE.
2.The in vitro apoptosis of human colon cancer cells induced by SFPS
Jinxing CHEN ; Xicheng HU ; Wei YANG ; Jian QIAN
Basic & Clinical Medicine 2006;0(02):-
Objective To study the anti-tumor effects of SFPS against human colon cancer cells.Methods Inhibition of the cell proliferation was measured by MTT assay.SFPS induced apoptosis of lovo and RKO cells was observed by electron microscopy and flow cytometry.The potential of SFPS in inhibiting lovo and RKO cells viability was assessed by MTT assay.Results SFPS significantly exhibited antiproliferative activity which depended on dosage.Morphological examination showed chromosomal condensation, karyotheca margination,cell shrinkage and the presence of apoptosis bodies.The overall effect of SFPS on the cell cycle distribution was examined by flow cytometry.However,it was also found that SFPS arrested the human colon cancer cell line RKO at G0/G1 phase,and the RKO cells at S phase decreased significantly,while no change in cell cycle distribution from SFPS treated lovo cells was observed.Conclusion SFPS may induce the apoptosis of lovo and RKO cells in vitro through anti-tumor proliferation.
3.The efficacy of post-operation rehabilitation treatment of calcaneus fracture as evaluated by Footscan system
Zhanfa CHEN ; Xicheng LI ; Haitao ZHAO ; Fengqi ZHANG ; Changling HAN ; Qi ZHANG ; Wei CHEN ; Yingze ZHANG
Chinese Journal of Physical Medicine and Rehabilitation 2008;30(3):181-184
Objective To evaluate the effects of post-operation rehabilitation treatment of patients with calcaneus fracture by dynamic plantar pressure analysis,and assess the value of the Footscan system.Methods Sixty-two patients with unilateral calcaneus fracture were randomly divided into a rehabilitation group and a control group.The patients in the rehabilitation group were given early,systemic standard rehabilitation treatment,while those in the control group took functional exercise following the doctors'advice.At 3 months and 6 months after operation,the plantar pressure distribution of the patients in both groups was analyzed with the Footscan system,respectively.Results After 3 months of treatment.there was statistically significant difference between the injured and the uninjured sides in both groups,with regard to the contact time,average plantar pressure and pressure-time integrals at different phases of gait.However,there was no significant difference between the injured and the uninjured sides after 6 months in rehabilitation group.But in control group,there was still statistically significant difference between the two sides with regard to the above parameters.Conclusion Early rehabilitation treatment could significantly improve the function outcome of patients with calcaneus fracture.Footscan System can objectively evaluate the recovery of the calcaneous fracture.
4.Study of the beam field of a new array ultrasound transducer.
Xicheng XIE ; Baikun XU ; Dewei CHEN
Chinese Journal of Medical Instrumentation 2010;34(4):250-254
This paper provides a new design of 12-element array ultrasound transducer. By modeling the beam field model of single element and array and comparing simulated and real ultrasound beam field test data, it can be demonstrated that 12-element array ultrasound transducer has a much better field performance than the 8-element transducer.
Equipment Design
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Ultrasonography, Doppler
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instrumentation
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Ultrasonography, Prenatal
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instrumentation
5.Postoperative rehabilitation of calcaneus fracture guided by the Footscan system
Zhanfa CHEN ; Lijie MA ; Mingke GUO ; Xicheng LI ; Fengqi ZHANG ; Yingze ZHANG
Chinese Journal of Physical Medicine and Rehabilitation 2009;31(6):405-408
Objective To test the Footscan system for guiding the postoperative rehabilitation of calcaneus fractures.Methods Sixty patients with unilateral calcaneus fracture were divided randomly into a rehabilitation group and a control group.Patients in both groups began a routine of functional rehabilitation training 24 h after a reduction and fixation operation.The patients in the rehabilitation group received individualized rehabilitation protocols based on regular dynamic evaluation of their plantar pressure using the Footscan system.Those in the control group were administered routine rehabilitation training without the personal modifications.At the 2nd and 7th month postoperation,the dynamic plantar pressure of both groups was evaluated and the functioning of their feet Was scored.Results At the 2nd month post-operation,there was no significant difference between the two groups in terms of subtalar ioint range of motion,the lateral deviation of pressure center,the time of heel touch with the ground,the maximum pressure at the lateral aspect of the calcaneus and impulsive force during walking.The functional evaluation scores were also not significantly different.At the 7th month post-operation,all the indices in both groups had improved significantly over the 2nd month,bulthe improvement in the rehabilitation group Was greater(except the time of heel touch with the ground).Conclusion The Footscan system can be a valuable tool for evaluating patients with calcaneus fracture and serve as a reference for planning rehabilitation interventions for such patients.
6.Research on relationships between enterprising and magnanimous psychological characteristics and coping modes in cancer patients
Lanlan WU ; Xuewei HUANG ; Lei CHEN ; Wen LI ; Xicheng WANG ; Meng XU
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(2):149-151
Objective To explore the relationship between enterprising and magnanimous psychological characteristics and coping modes in cancer patients.Methods Totally 450 cancer patients were randomly chosen to analyze the correlation using enterprising and magnanimous questionnaires and cancer coping modes questionnaires.T-test,Variance analysis and Pearson analysis were employed for statisticals.Results (1) The enterprising and magnanimous psychological characteristics:cancer patients generally got lower scores in the dimensions of enterprising,magnanimous,and total score (59.30±8.09,31.98±6.24,27.32±4.02,respectively) than healthy population (67.44±5.60,34.72±4.57,32.72±3.23,respectively).In demographic level,male and female cancer patients' scores were also lower than the healthy ones'.The higher academic backgrounds they had,the better enterprising and magnanimous psychological attitudes they embraced.In the comparison of occupation,professionals in administrative and companies scored the highest in the dimensions of enterprising,workers in special techniques,commercial and service industries scored higher in the dimensions of magnanimous.All the differences were significant statistically (P<0.05).(2) Correlation analysis:the correlation index between psychological characteristics of enterprising and magnanimous and the coping modes in cancer patients was 0.463,with a positive correlation(P<0.01),and the indexes among in the dimensions of enterprising and confrontation were regarded as a positive correlation (r=0.415),and negative correlations (r =-0.139,r =-0.047,respectively) with avoidance and suppression and resignation (P<0.01).Conclusion The enterprising and magnanimous mental level of cancer patients is lower,which is related to their inappropriate responses of avoidance and suppression and resignation.
7.Fetal ECG monitoring system based on MCU processing.
Gang HU ; Wei CHEN ; Xicheng XIE ; Hao ZHANG
Journal of Biomedical Engineering 2004;21(6):1011-1013
In order to monitor the fetus in labor, the signal characteristic from fetal scalp electrode is researched, An adaptation algorithm and a peak to peak detecting technology are adopted in signal processing, and an adaptation gain control method is used to eliminate disturber from base-line shift. A fetal ECG monitoring system is designed on the basis of C8051F020 MCU.
Adult
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Electrocardiography
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instrumentation
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Female
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Fetal Heart
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physiology
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Fetal Monitoring
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instrumentation
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Humans
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Pregnancy
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Signal Processing, Computer-Assisted
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instrumentation
9.Mortality surveillance of children under five years old in Xicheng District of Beijing during 2016-2021
HE Shuqing, ZHANG Xiaowen, CHEN Huiyan
Chinese Journal of School Health 2022;43(9):1380-1382
Objective:
To analyze under 5 years old mortality rate during 2016-2021 in Xicheng District, Beijing, and to provide scientific basis for further reducing infant mortality rate and under 5 years old mortality rate.
Methods:
A descriptive statistical analysis was conducted on the mortality surveillance data of children under 5 years old reported by Preventive Health Department of Xicheng District Community Health Service Center during 2016-2021.
Results:
During 2016-2021, under 5 mortality, infants and newborn mortality in Xicheng District decreased from 2.31‰, 1.85‰ and 1.12‰ to 1.55‰, 1.07‰ and 0.48‰ respectively. There was no significant difference in mortality rate between 2016 and 2021( P >0.05). The leading cause of death among children under 5 years of age included other congenital abnormalities(except congenital heart disease and down s syndrome)(18.79%), preterm birth/low birth weight (16.36%) and birth asphyxia(7.88%). Infant deaths accounted for 69.23%- 80.00 % of deaths of children under 5 years of age, and neonatal mortality accounted for 44.44%-71.43% of infant mortality.
Conclusion
It is necessary to carry out relevant preventive intervention and quality management based on the main causes of death, and to further improve the management of critically ill neonates and reduce neonatal mortality.
10.Clinical study on the different lengths of inferior vena cava stent implantation for non-thrombotic iliac vein lesions
Xicheng ZHANG ; Yuanhu JING ; Zhaolei CHEN ; Yuan SUN ; Miao XU
International Journal of Surgery 2018;45(11):740-744,封3
Objective To assess the safety and influence of the stents extended into inferior vena cava in patients with non-thrombotic iliac vein lesions (NIVLs) on the bilateral iliac vein blood flow.Methods We retrospectively reviewed data from July 2008 to June 2017 in 197 patients with NIVLs who underwent iliac vein stenting and complete follow-up was obtained at our institution.Of these patients,stents extended into IVC more than 10 mm in 141 cases,less than 5 mm in 22 cases,and 34 cases were between 5 and 10 mm.Restenosis and thrombosis of bilateral iliac vein and patency of these stents were assessed in the follow-up.The count data were expressed by percentage (%),and the sample comparison rate was analyzed by Fisher exact test formula.The measurement data were first tested for normal distribution and homogeneity of variance,and then corrected t test.Results The two hundred and five iliac vein stents were placed in 197 patients.During a mean follow-up of 58.7 months (6 to 98 months),there were no thrombosis occurred in the contralateral iliac vein,6 patients suffered restenosis or new thrombosis in the stents,the incidence between stenting positions less than 5 mm (13.6%,3/22) and those more than 5 mm (3.43%,6/175) was sighificantly different (P <0.001),and 5 of 6 patients had a good patency after endovascular therapy.During the fllow-up,the primary and assisted-primary patency rates were 97.0% and 99.5%.Conclusions From these data,it appears that there is a very high patency rates of the stenting treatment for the NIVLs,and it is safe for the stents extended into the IVC,stenting across the iliocaval confluence can result in a small number of new contralateral thromboses.Moreover,the risk of stents restenosis or occlusion is high when stents are not extended into IVC.