1.Revision of Assessment of Consonant Vowel and Tone Recognition for Cochlear Implanted Children
Jianju LIU ; Fang ZHANG ; Xibin SUN
Chinese Journal of Rehabilitation Theory and Practice 2013;19(11):1024-1028
Objective To revise the assessment of consonant vowel and tone recognition for cochlear implanted children. Methods 300 normal hearing children aged 2~6 years old were assessed with word lists for consonant and vowel recognition, and analysed with equivalency analysis. Results The incidence of consonant vowel and tone recognition was less than 90% in children aged 2~3 years old, but more than 90% in those aged 3 or more. Conclusion The assessment of consonant vowel and tone recognition for cochlear implanted children aged of 3 and above has been modified, and the assessment for those aged 2~3 years old has been developed.
2.Application status quo of sentinel lymph node detection in mediastinal lymphadenectomy of non-small cell lung cancer
Shaoyu HAO ; Pingping SONG ; Xibin LIU ; Baijiang ZHANG
Journal of International Oncology 2011;38(11):845-848
In surgical operation of the non-small cell lung cancer (NSCLC),the resection of lymph node involvement is highly correlated with the prognosis of NSCLC patients.The precise estimation of localized lymph node involved and the determination of relevant pattern of lymphadenectomy are the significant predictors for the prognosis and postoperative treatment in NSCLC patients.Therefore to identify the lymph node metastasis earlier has more important significance for tumor clinical staging and making therapeutic schedule.In recent years,the value of sentinel lymph node (SIN) has attracted more and more researchers attention in detecting the occult lymph node micrometastases and surgical staging.
3.Clinical Observation Laparoscopy Combined with Dienogest and TCM in the Treatment of Endometriosis
Yuhong ZHANG ; Xiaojuan LIU ; Xibin SUN ; Jiangping CHEN ; Guiqing JIAO
China Pharmacy 2015;26(35):4960-4962
OBJECTIVE:To compare therapeutic efficacy and safety of laparoscopy combined with dienogest and laparoscopy combined with dienogest and TCM in the treatment of endometriosis. METHODS:126 endometriosis patients were selected and divid-ed into control group and observation group,with 63 cases in each group. Control group received combined with dienogest(25 mg/time,qd);observation group was additionally given TCM on the basis of control group. Therapeutic efficacy,recovery time of ovula-tion,menstrual recovery time and ADR were compared between 2 groups,and recurrence and pregnancy of them were followed up for 2 years. RESULTS:The total effective rate of observation group (93.65%) was significantly higher than that of control group (80.96%),with statistical significance (P<0.05). The menstrual recovery time and recovery time of ovulation in observation group were significantly shorter than control group,with statistical significance (P<0.05). The incidence of ADR in observation group (9.52%)was significantly lower than control group(26.98%),with statistical significance(P<0.05);the recurrence rate of observa-tion group (4.76%) was significantly lower than that of control group (17.46%),with statistical significance (P<0.05). In 2-year follow-up,there were 23 pregnancy patients in observation group,which was significantly higher than that of control group (9 cas-es),with statistical significance (P<0.05). CONCLUSIONS:Laparoscopy combined with dienogest and TCM in the treatment of endometriosis have better clinical effect,higher safety and lower recurrence rate. The patients are easily pregnant.
4.Effects of Isokinetic Strength Training on Upper Limb Motor Function and Activities of Daily Living in Stroke Patients with Hemiplegia
Zhenglu YIN ; Xiaoyun ZHU ; Zhangling FAN ; Xibin ZHANG ; Kui WANG
Chinese Journal of Rehabilitation Theory and Practice 2017;23(9):1086-1090
Objective To study the effect of isokinetic strength training on upper limb motor function and activities of daily living (ADL) in stroke patients with hemiplegia. Methods From January to December, 2016, 56 stroke patients with hemiplegia were randomly di-vided into control group and observation group equally. Both groups received routine rehabilitation training, and the observation group ac-cepted hemiplegic limb flexor and extensor muscle isokinetic strength training in addition, for four weeks. They were assessed with Fugl-Meyer Assessment-upper limb (FMA-UL), modified Ashworth Scale (MAS), modified Barthel Index (MBI) and biomechanical index-es of elbow flexion and extension with Biodex System-4 before and after treatment. Results The scores of FMA and MBI improved after treatment (t>7.083, P<0.001) in both groups, and improved more in the observation group than in the control group (t>2.369, P<0.05). The peak torque, total work and average power at 60°/s and 120°/s angular velocity of both flexor and extensor improved in both groups (t>2.149, P<0.05), and those of the extensor improved more in the observation group than in the control group (t>2.027, P<0.05), except the peak torque at 60°/s angular velocity. Conclusion Isokinetic strength training can improve the motor function of upper limbs and activities of daily living in stroke patients with hemiplegia.
5.Observation of intermediate-term curative effect of percutaneous laser disc decompression for the treatment of cervical spondylotic radiculopathy
Longxi REN ; Han GUO ; Tongtong ZHANG ; Zhengfeng HAN ; Jian YIN ; Xibin LIANG ; Xiaggfei ZHANG
Chinese Journal of Orthopaedics 2011;31(10):1044-1048
ObjectiveTo observe the 2-8 years' follow-up results of percutaneous laser disc decompression(PLDD) on cervical spondylotic radiculopathy,and to identify factors affecting the outcome of PLDD.MethodsEighty-seven patients with cervical spondylotic radiculopathy were treated consecutively by PLDD in our hospital from December 2002 to June 2009,who were followed up for 2-8 years.There were 32males and 26 females,with the mean age of 51.8 years (range,26-74).The results were evaluated according to the Japanese Orthopedic Association's score of cervical spondylotic radiculopathy(JOA 20 score) and numeric rating scales (NRS) after surgery.Two years after the operation,the excellent and good rate of JOA score of patients with different genders,ages and duration of each subgroup will be compared.ResultsThe excellent and good rate were 37.9%,51.7%,65.5%,81.0%,82.8%,80.9%,72.4% and 72.7% at 1,3,6months and 1,2,4,6,8 years after operation respectively.Significant difference was found between the time points of 6 months to eight years after operation and that of one month after operation.The NRS score of the pain symptoms at the final follow-up was significantly reduced(P<0.05).The excellent and good rate of patients whose course of disease (93.3%) was less than 18 months was significantly higher than that of those whose course of disease was over than 18 months(71.4%) two years after operation (P<0.05).Conclusion The intermediate-term curative effect of PLDD for the treatment of cervical spondylotic radiculopathy is reliable and stable,and the postoperative curative effect may be influenced by patients' duration of disease.
6.Application of high volume continuous blood purification in the treatment of multiple organ dysfunction syndrome
Qichun ZHANG ; Xibin FANG ; Zhiye LI ; Weihong CHEN ; Xiaobin NI ; Suzhi CHEN ; Yang LUO ; Jiping CHEN
Chinese Journal of Primary Medicine and Pharmacy 2012;19(17):2598-2599
Objective To compare the effect of high volume continuous blood purification (CBP) with routine CBP on multiple organ dysfunction syndrome(MODS).Methods 38 patients with MODS were randomly divided into high volume CBP group( treatment group,18 cases) and routine CBP group (control group,20 cases).And they were respectively detected on mean arterial pressure(MAP),dosage of Dopamine,PaO2/FiO2,APACHE [ score,lactic acid,length of stay and mortality in ICU post-treatment 24h and 48h.Results Compared with control group,MAP and PaO2/FiO2 on treatment group were more higher( P < 0.05 ),while dosage of Dopamine,APACHE Ⅱ score,lactic acid were significantly shorter than these of treatment group( P < 0.05 ),and length of stay and mortality in ICU were significantly lower than those of treatmen group [ ( 8.54 ± 4.15 ) d vs ( 11.82 ± 5.76) d,P < 0.05:22.2% vs 35.0%,P <0.05 ].Conclusion High volume CBP could reduce the mortality in ICU compared with control group routine CBP.
7.Effect of bronchofibroscope joint mechanical ventilation on the treatment of the geratic surgery postoperative patients with acute respiratory failure
Qichuang ZHANG ; Xibin FANG ; Hukun GUO ; Qinggao LIAO ; Jiping CHEN ; Haisen GUO
Chinese Journal of Primary Medicine and Pharmacy 2010;17(1):14-15
Objective To explore the effect of bronchofibroscope joint mechanical ventilation on the treatment of the geratie surgery postoperative patients with acute respiratory failure.Methods 62 geratic surgery postoperagedative patients with acute respiratory failure were randomly divided into two groups(control group and treatment group).The treatment group(n=32) applyed bronchofibroscope aspiration and/or bronchial lavage joint mechanical ventilation.The control group(n=30) were treated only with mechanical ventilation.Compare with two groups parameters of arterial blood gas,the time of mechanical ventilation,average in ICU,success rate one time pull out windpipe conduit and case fatality rate.Results Compare with the control group,the treatment group patients parameters of arterial blood gas had been improved significantly;the time of mechanical ventilation and average in ICU had been cut short significantly;all showed a statistical difference(P<0.05).Success rate one time pull out windpipe conduit and case fatality rate were better than the control group,but there were no significant difference(P>0.05).Conclusion The effect of bronchofibroscope joint mechanical ventilation to treat the geratic surgery postoperative patients with acute respiratory failure was better than only mechanical ventilation,which can decrease the time of mechanical ventilation and average in ICU.The method was worth to spread.
8.Fast violet B salt staining for bone marrow stromal cells and its clinical significance
Xubo GONG ; Xianguo WU ; Xingguo LU ; Lijuan YAN ; Xibin XIAO ; Genbo XU ; Xiaohong ZHANG ; Xiaoying ZHAO
Chinese Journal of Laboratory Medicine 2008;31(8):890-893
Objective To establish a quick method to identify BMSC by fast violet B salt staining and evaluate the clinic value. Methods Smears of separated and cultured BMSC, bone marrow, pleural and ascitic fluids were made, then the staining of fast violet B salt was performed. The BMSC in aplastic anemia (AA), high hyperplasia and normal groups were counted and compared with each other. Meanwhile, the diagnostic value of this method to AA was evaluated. Results The cytoplasm of BMSC presented mauve, while the nucleus were negative, other cells such as myelocytes, nucleated erythrocytes, megakaryocytes, monocytes, macrophages, lymphocytes and plasmacytes were negative. The count of BMSC in AA, high hyperplasia and normal group was 1.07 ± 0. 29, 2. 26 ± 0. 37 and 1.58±0. 33, respectively. Significant differences were found between AA and high hyperplasia groups, AA and normal groups, high hyperplasia and normal groups, respectively (P < 0.01). The sensitivity, specificity, positive likelihood ratio and negative likelihood ratio of this method for diagnosis of AA were 90%, 93%, 12. 86 and 0. 11,respectively. Conclusions The fast violet B salt staining is simple and convenient. It could be used to identify BMSC and play an important role in judging the hyperplasia extent and differentiation of AA.
9.Randomized controlled clinical trial of nedaplatin combined with gemcitabine and cisplatin combined ;with gemcitabine in the treatment of advanced lung squamous cell carcinoma
Jing ZHANG ; Qun CHEN ; Mingyao KE ; Xibin ZHUANG ; Qin SHI ; Yazhi YONG ; Cheng HUANG
Journal of International Oncology 2017;44(1):15-18
Objective To explore the efficacy and adverse reaction of nedaplatin (NDP)+gemcitabine (GEM)and cisplatin (DDP)+GEM for advanced lung squamous cell carcinoma.Methods A total of 1 01 cases advanced untreated patients from September 201 2 to December 201 3 were randomly divided into 2 groups using random number table method:69 patients in the observation group accepted NDP+GEM treatment and 32 patients in the control group received DDP +GEMtreatment.The objective response rate (RR),disease control rate (DCR ) and progression-free survival (PFS ) and adverse reaction were collected and evaluated. Results RR was 28.6%(1 8/63)in the observation group and 1 5.6%(5/32)in the control group,DCR was 81 .0%(51/63)in the observation group and 68.8%(22/32)in the control group (χ2 =1 .36,P=0.24;χ2 =1 .67,P=0.20).The median PFS was 4.52 months and 4.01 months in the observation group and control group (χ2 =0.09,P=0.73).The major adverse reaction was myelosuppression in both groups (33.3% vs.37.5%,χ2 =0.1 7,P=0.68).The incidence ofⅢ-Ⅳ grade nausea and vomiting was lower in the observation group, compared with the control group (1 4.5%vs.56.3%,χ2 =1 9.02,P=0.05).Conclusion NDP combined with GEM in advanced lung squamous cell carcinoma of the first-line treatment has equivalent efficacy to DDP+GEM, with lower incidence of adverse reaction,which is worthy of further dissemination of research.
10.Application of language function assessment in children with hearing impairment
Liyan WANG ; Xibin SUN ; Mingchen LV ; Chengyi QU ; Jianju LIU ; Duanxia WANG ; Junlan CHEN ; Fang ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2011;17(7):676-679
Objective To study the characteristics of language function development and establish the reference standards in children of4~6 years old. Methods 616 hearing normal children at the age of 3~7 from 13 provinces in China were assessed with Language FunctionEvaluation for Hearing-impaired Children. 583 usable data were analyzed via SPSS 17.0. Results The older the children were, the highertheir scores of language function evaluation were (P<0.001). The differences between boys and girls on coordination function and relaxationfunction were significant (P<0.01). The girls were better than the boys. The reference standards of children of 4~6 years old were set downbased on the regression analysis. Conclusion There are some laws on children's language function development. The reference standards ofchildren by 4~6 years old has been developed.