It is fewer that sudden deafness in children,especially sudden deafness in both ears in a short term and no much reports about such cases.This paper reported 3 cases suffer from sudden deafness at 9.They all got good effect by medication of little Chaihu soup(a traditional Chinese medicine)combined Dexamethasonum.It is attach importance to the wide range of suffering from sudden deafness.

Objective To analyze the influence of cochlear implant age, sexuality, and rehabilitation time on tone recognition ability.Methods 272 hearing-impaired children aged 2~6 years old with cochlear implants were enrolled in the study. By three factors mixed design,the sexuality, age and rehabilitation time of the children (independent variable) and the tone recognition rate (dependent variable) wereanalyzed. Results The rehabilitation time and age had significantly main effect in tone recognition rate (P<0.001), but age (P>0.05). The interactionof rehabilitation time and age also had main effect (P<0.001). Conclusion Age and rehabilitation time are important factors fortone recognition ability. The younger the children are, the better the recognition ability is with the extension of rehabilitation time.

This paper summarized the development of home early intervention program for infants and toddlers with hearing impairment,including the elements, effect, and participators.

Objective To revise the assessment of consonant vowel and tone recognition for cochlear implanted children. Methods 300 normal hearing children aged 2~6 years old were assessed with word lists for consonant and vowel recognition, and analysed with equivalency analysis. Results The incidence of consonant vowel and tone recognition was less than 90% in children aged 2~3 years old, but more than 90% in those aged 3 or more. Conclusion The assessment of consonant vowel and tone recognition for cochlear implanted children aged of 3 and above has been modified, and the assessment for those aged 2~3 years old has been developed.

Objective To explore the death distribution characteristics of heart disease and the strategies for its prevention and control, based on data of the death rates of different heart diseases among the residents of Henan province from 1987 to 2006. Methods The mortality rates of heart diseases during past 20 years were analyzed by age, sex, living places (urban vs. rural), and by patterns of heart disease as well with SAS9.1. Results In these past 20 years, the mortality rates of heart diseases ranged from 60.93 to 85.10 per 100 000. The annual mortality rate averaged 74.47 per 100 000, and the standardized mortality rate was 61.10 per 100 000, which equaled to 13.14% of the total death number. The death rates of heart diseases had increased significantly with age. Among the male and female of the cities or the rural, the death was mainly due to coronary heart disease. Concludes According to the death distribution characteristics of heart diseases in Henan Province, the prevention and control efforts should focus on the population over 35 years of age.

Objective To estimate the death number of children under age 5 in Linzhou city during 2004 to 2005 using the capture-recapture method, and to evaluate the integrality of data about the children death report in all death cause registry. Methods The data of children death were collected from sources of registry office, village symposium for the 3rd national death cause survey and police registries. Cases in every source were matched on the name, sex, age, date of death, cause of death and resident address. To fit for dependencies and heterogeneities between three sources, a log-linear model in stratified age and gender was used to estimate the death number of children which did not appear in three sources. Results It was reported that death number of children under age 5 was 359 and the mortality was 2.16% for combined three sources; but from the registry office, the number and mortality were 291 and 1.75%, respectively. The capture-recapture method estimated that the number of death was 398 and the mortality was 2.39%. Under-reporting rates of registry and aggregate database were 26.9% and 9.8%. Female deaths were more likely to go unreported. Under-reporting rates of registry got higher with the decrease of the age at death. Conclusion Registry office or aggregated database underestimated the death number of children under age 5. On the base of data which were collected from police, village and registry, using the capture-recapture method can adjust the death number of children.

Objective To assess the hearing, language and intelligence in prelingually deafened children with multichannel cochlear implant ,and to analysie the basic pattern of speech recognition and language development.Methods 42 prelingually deafened children with cochlear implant participated in this study. The “Evaluating method on hearing and language rehabilitation in deafened children” was used as test material.Results The average hearing of these deafened children with cochlear implant was 35 dB HL.The correct recognition rate and language ability were escalating with prolonging the implanted time. Subjects showing significant progress half year after operation indicated that the cochlear implant could promote prelingually deafened children to develop their hearing and language level.Conclusion With scientific and systemic rehabilitation training, prelingually deaf children, who have ordinary intelligence,will have significant progress half year after the operation.

OBJECTIVE:To compare therapeutic efficacy and safety of laparoscopy combined with dienogest and laparoscopy combined with dienogest and TCM in the treatment of endometriosis. METHODS:126 endometriosis patients were selected and divid-ed into control group and observation group,with 63 cases in each group. Control group received combined with dienogest(25 mg/time,qd);observation group was additionally given TCM on the basis of control group. Therapeutic efficacy,recovery time of ovula-tion,menstrual recovery time and ADR were compared between 2 groups,and recurrence and pregnancy of them were followed up for 2 years. RESULTS:The total effective rate of observation group (93.65%) was significantly higher than that of control group (80.96%),with statistical significance (P<0.05). The menstrual recovery time and recovery time of ovulation in observation group were significantly shorter than control group,with statistical significance (P<0.05). The incidence of ADR in observation group (9.52%)was significantly lower than control group(26.98%),with statistical significance(P<0.05);the recurrence rate of observa-tion group (4.76%) was significantly lower than that of control group (17.46%),with statistical significance (P<0.05). In 2-year follow-up,there were 23 pregnancy patients in observation group,which was significantly higher than that of control group (9 cas-es),with statistical significance (P<0.05). CONCLUSIONS:Laparoscopy combined with dienogest and TCM in the treatment of endometriosis have better clinical effect,higher safety and lower recurrence rate. The patients are easily pregnant.

Objective To analyze and compare the fluorescence in situ hybridization(FISH) and immunohistochemical(IHC) for detecting HER-2 gene amplification and protein expression in breast cancer tissues .Methods 110 cases of breast cancer from Janu-ary 2008 to May 2012 receiving the modified radical mastectomy were selected .The resected breast cancer tissue was detected by FISH and IHC and the detected results were performed the comparative analysis .Results Among 110 cases of breast cancer tissue , 25 cases(22 .73% ) were the HER-2 protein expression(+ + + ) ,44 cases(40 .00% ) were(+ + ) ,26 cases(23 .64% ) were(+ ) and 15 cases(13 .64% ) were(-) .Among 110 cases ,the gene amplification was in 28 cases(25 .45% ) and no gene amplification was in 82 cases(74 .55% ) .The positive(+ + + ) of the IHC detection was coincident with that of FISH ,and the negative(+ /-) of the IHC detection was also coincident with that of FISH ,there was statistical difference between the suspicious positive of the IHC de-tection and the results of FISH (P<0 .05) .But the total coincidence of the IHC detection results and FISH test results was 89 .29%(25/28) ,and the two detection methods had the positive correlation (χ2 =84 .89 ,P<0 .01) .Conclusion The positive and negative expression of the IHC detection has better consistency with that of the FISH detection .However ,the coincidence of the IHC suspi-cious positive expression and the FISH results is poor ,indicating that the suspicious positive sample of the IHC detection needs to be detected by the FISH detection .

Background and purpose:Henan is a big agricultural province and the high mortality rate of digestive system cancer threatened the life and the health of the people.In order to make some good strategies,we investigated the mortality rate and characteristic distribution of digestive system cancer in Henan province. Methods :The mortality and age-standardized mortality rate from 1987 to 2006 in Henan province were analyzed by using the data from registration system of all causes of death from 1/10 population in Henan province. Results :The crude mortality rate of digestive system cancer from 1987 to 2006 in Henan province was 81.95/10 5,and the age-standardized mortality in Chinese standard population was 71.31/10 5,which accounted for 71.29% of all cancers.The mortality rates,age-standardized mortality in male was 101.17/10 5 and 94.81/10 5 respectively,compared to 61.58/10 5 and 49.28/10 5 respectively in female.The foremost four in rank of the digestive system cancer were gastric cancer,esophageal cancer,liver cancer and intestinal cancer.The mortality of digestive system cancer has descended in the recent twenty years.Comparing in 1987 and in 2006,the age-standardized mortality rates of gastric cancer and esophageal cancer had decreased significantly from 30.38/10 5 to 21.27/10 5 and from 34.12/10 5 to 15.70/10 5 respectively.The death rate of intestinal cancer remained constant.But age-standardized mortality rate of liver cancer had increased significantly from 12.45/10 5 in 1987 to 18.26/10 5 in 2006. Conclusions :The distribution of death rate of digestive system cancer had changed greatly,so the prevention measures have to be changed accordingly.