1.Progress of surgical approach to hysterectomy
Mengmeng DU ; Hong LIU ; Rongrong WANG ; Shouye MA ; Xiazi NIE
Journal of Chinese Physician 2016;18(1):157-160
Nowadays,with the introduction of the concept of minimally invasive surgery,laparoscopic surgery which occupied the mainstream operation method,vaginal surgery,and abdominal surgery were three main ways of gynecological surgery.Hysterectomy operation method as the routine operation of gynecology was changed as well.Laparoscopic hysterectomy has replaced transvaginal hysterectomy and transabdominal hysterectomy gradually.Historical development,operation indication,and advantages and disadvantages of hysterectomy are summarized in this article.
2.Analysis on the Satisfaction of Family Doctor Services among Urban Residents in Ankang, Shaanxi
Xiazi LIU ; Qinxiang XUE ; Lili JIA
Chinese Medical Ethics 2017;30(9):1146-1150,1163
Objective:To investigate the satisfaction of family doctors services among the contracted community residents,so as to provide evidence for improving the related system of family doctors.Methods:Two community health service centers in Hanbin District of Ankang were selected as the investigation sites and 805 over-65-year residents were recruited and interviewed using cluster sampling method.Results:The three most satisfactory items for community doctor services were family doctors' attitude (86.0%),the convenience of appointment and service (80.3%) and the degree of listening and explaining the disease (77.1%).Conclusion:Overall,the residents are generally satisfied with the family doctor services,but there still exists much room for improvement.We must increase propaganda of family doctor services in the process of implementation,raise the awareness of family doctor services in residents,establish and improve the mechanism of training,introduction,evaluation and incentive of family doctors,and improve the overall quality and service ability of family doctors.
3.Research progress of molecular docking in screening anti-cervical cancer drugs
Dan WANG ; Wenyan ZHANG ; Renjie LUO ; Yuanjing CHEN ; Xue HAN ; Bo QU ; Shifang FENG ; Xiazi NIE ; Huiling LIU
Chinese Journal of Clinical Pharmacology and Therapeutics 2024;29(8):955-960
Cervical cancer is one of the most common gynecological malignant tumors,the five-year survival rate decreased significantly in the case of lymph node metastasis and distant metasta-sis,so the development of new anti-cervical cancer drugs is of great significance for the treatment of cervical cancer.Molecular docking technology is one of the most commonly used research methods in computer aided drug design,which is widely used in screening the effective components of drugs,finding the targets of drugs acting on tumors and exploring the mechanism of antineoplastic drugs.This paper reviews the molecular docking technology in the screening of anti-cervical cancer drugs,the determination of anti-tumor targets and the mechanism of anti-cervical cancer,in order to provide more sufficient theoretical basis for the screening of anti-cervical cancer drugs and new drug research and development.