Day-care chemotherapy boasts the advantage of shorter treatment time, higher treatment efficacy and lower patients′ burden, as compared to the conventional hospitalization pattern. In view of treatment needs of patients, better therapeutic outcomes and patient satisfaction, the authors analyzed the problems and shortages in the current management mode of chemotherapy in breast cancer care. With the specialized department taking the lead, a multidisciplinary collaboration was built among doctors, nurses and pharmacists.This integrated new mode combining doctors, nurses, pharmacists and patients together was further optimized. This new mode can provide a safer and easier treatment and set up a whole process management for chemotherapy of breast cancer care.

Objective To investigate the difference of depressive symptoms between adolescents and adults,and to provide possible basis for early detection of adolescent depression.Methods From July 2021 to June 2022,a total of 4 096 patients with"depression"in the psychiatric clinic of the First Affiliated Hospital of Chongqing Medical University were selected as the research objects.They were divided into the adolescent group(n=2 439)and adult group(n=1 657)according to their ages,and the results of self-rating depression scale(SDS)and symptom checklist 90(SCL-90)were collected and analyzed.Results There were significant differences in nationality,residence,native place,family history and degree of depression between the two groups(P<0.05).The adolescent group has more severe depressive symptoms,which were mainly manifes-ted in negative ideas,obsessive-compulsive symptoms,hostile and interpersonal relationship,and psychotic symptoms(P<0.05).The adult group showed more obvious in sleep(P<0.05).Conclusion Early inter-vention should be carried out for adolescents'depressive symptoms such as negative thoughts.