Objective To evaluate the value of occlusion of congenital heart disease(CHD) combined with pulmonary artery hypertension (PH) by color Doppler echocardiography. Methods Experimental transcatheter closure was performed in 209 patients suffering from CHD with PH, which included 86 cases of atrial septal defect(ASD), 17 cases of ventricular septal defect(VSD) and 106 cases of patent ductus arteriosus(PDA). All patients were occluded experimentally in order to determin whether or not to be the dynamia type of PH. During the process, whether pulmonary arterial systolic pressure(PASP) was stepped down and the degraded degree were detected by echocardiography. Results After 209 cases were done trial occlusion from half an hour to an hour,PASP of 136 cases of lihgt PH patients dropped to normal; in 46 cases of midrange PH patients,PASP of 30 cases dropped to normal,PASP of 16 cases dropped to light; in 17 cases of sever PASP patients,PASP of 9 cases dropped to midrange,PASP of 6 cases stepped down over 30 mmHg,whieh those patients were occluded permanently. PASP failed to respond in 2 cases sever PH after the procedure,implied resistant PH, the permanent transcatheter closure was not recommended and the device was removed. Conclusions PASP can be estimated by color Doppler echocardiography before,during and after occlusion,which could judge reversibility of PH.