1.Effect of nursing intervention on depression of patients with acute stroke
Xiuqun YAN ; Huizhen ZHANG ; Xiaoyuan SONG
Chinese Journal of Practical Nursing 2008;24(24):21-22
Objective To probe the effect of nursing interventions on depression of patients with acute stroke.Methods 72 cases of stroke patients with depression screened by Hamilton depression scale (HAMD)were divided into the intervention group and the control group with 36 cases in each group.The control group received routine treatment.The intervention group wag given nursing intervention based on routine treatment.The effect was assessed before and after 3,6 and 12 months of intervention with Zung self-rating depression scale(SDS)and improved Rankin scale(MRS). Results The value of SDS after 3,6 or 12 months was significantly lower than that of the control group(P<0.05),and the value of MRS was significantly higher than that of the control group(P<0.05).Conclusion Nursing intervention can reduce depression in patients with post-stroke depression.
2.Measuring Method of Cardiac Output and Its Progress.
Xiaoyuan YAN ; Shumei GAO ; Yilin SONG
Journal of Biomedical Engineering 2015;32(3):697-701
As one of the important indexes for the diagnosis and treatment of cardiovascular diseases, cardiac output can reflect the state of cardiovascular system timely, and can play a guiding role in the treatment of related diseases. In recent years detection technology of cardiac output has caused great attention, especially minimally invasive and non-invasive methods. In this paper, the principle of non-invasive detection methods and their recent developments are described, and various detection methods are also analyzed.
Cardiac Output
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Cardiovascular Diseases
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diagnosis
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Cardiovascular Physiological Phenomena
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Humans
3.Application of problem-based learning in clinical teaching of gynecology and obstetrics
Xiaonan YAN ; Xiaoyuan LU ; Qiuyu HAN
Chinese Journal of Medical Education Research 2006;0(10):-
PBL is problem-based and student-centered learning pattern. PBL has been proved to be an effective teaching,which is helpful to improving the students’learning enthusiasm and learning efficiency,and to training their clinic thoughts and the capability of teamwork.
4.The relationship between the tumor necrosis factor(TNF)-alpha and glucose levels in gestational diabetes mellitus
Hongchao YAN ; Xiaoyuan LU ; Jiaqiang XUE
Chinese Journal of Postgraduates of Medicine 2006;0(09):-
Objective To assess the clinical significance of changes tumor necrosis factor(TNF)-alpha level and the relationship between serum TNF-? and glucose levels in patients with gestational diabetes mellitus(GDM). Methods 71 patients with gestational diabetes mellitus were enrolled.40 normal pregnant women were assigned to be control group.Then the concentrations of blood glucose and TNF-? were determined. Results Blood TNF-? level in GDM patients was signficantly higher than that in normal pregnant women(P
5.Stress and reproductive endocrine dystunction
Xiaoyuan LIAN ; Yan DING ; Juntian ZHANG
Chinese Pharmacological Bulletin 2001;17(1):5-8
Physical and psychological stresses inhibit or harm reproductive endocrine especially female one at many levels of hypothalamo-pituitary-gonadal (HPG) axis, and result in subhealth conditions or clinic diseases in reproductive endocrine. The hypothalamic corticotropin-releasing factor (CRF) and adrenal glucocorticoids (GCS) overreleases and other neuroendocrine alterations induced by stress are implicated in the mechanisms responsible for the disturbance of reproductive endocrine. The declines in activities of synzyms for reproductive hormones cause sexual hormones reduces and disfunction in reproductive endocrine system.
6.Experience in nursing of patients with Robertsonian translocation receiving pre-implantation genetic diagnosis
Yuying YAN ; Lanfeng XING ; Xiaoyuan ZHANG
Chinese Journal of Practical Nursing 2015;31(2):127-129
Objective We sought to summarize the experience in nursing the patients of Robertsonian translocation receiving pre-implantation genetic diagnosis (PGD).Methods Thirty-eight patients with Robertsonian translocation received PGD.These patients received health education and psychological nursing except for routine therapy and nursing.Results All these patients had no obvious negative emotion and complied with the therapy.Nine patients were successfully pregnant and pregnancy rate was 23.7%,7 of them delivered healthy neonates.Conclusions Health education,psychology nursing together with controlled ovarian stimulation,egg retrieval and embryonic transplantation can reduce negative emotion,improve compliance of therapy,and benefit the process of PGD and clinical outcomes.
7.Value of combined CA125, CT and MRI in diagnosing the ovarian thecoma
Yan ZHANG ; Xiaoyuan QI ; Lixia WANG ; Zehui SUN
Clinical Medicine of China 2015;31(8):759-762
Objective To discusses the value of combined CA125 and CT/MR/ in diagnosing the ovarian thecoma.Methods Forty cases of patients with ovarian thecoma were retrospectively analyzed.The results of CA125 and the appearance of CT and MRI were recorded,the value of CA125 changes and CT/MRI features was analysed in the diagnosis of ovarian thecoma.Results The value of CA125 elevated in 17 cases of ovarian thecoma,and showed statistical significance in the ratio((12/35 vs.5/5;x2=2.274,P=0.046) and the levels of the value of CA125 ((90.24 ± 18.56) U/ml vs.(243.35 ± 20.45) U/ml;t =7.780,P =0.002).Compared with 40 cases of control group,elevated CA125 level showed no obviously statistical significance (t =5.348,P=0.22).Forty patients in CT and MRI were all single lesion,30 cases were solid neoplasm,the rest were cystic-solidary lesions or priority of cystic component,75% lesions were more than 5 cm,9 cases of lesions contains calcification.In pre-enhanced CT and MR/scan the lesions showed iso-density or signal-intensity,mildly enhanced;Twenty-two patients with ascites and 11 cases with symptoms in the elevating of estrogen.Combined the results of CA125 and the apperaance of CT and MR/,the accuracy of the diagnosis in ovarian thecoma was 85%.Conclusion CT and MR/imaging combining with CA125 can improve the diagnosis accuracy of ovarian thecoma.which should be given priorities.
8.Restrained Factors in Disposal of Medical Dispute about Nosocomial Infection
Meihua LAN ; Yan ZHANG ; Xiaoyuan SHI ; Fuxiang REN
Chinese Journal of Nosocomiology 2006;0(09):-
OBJECTIVE To investigate the restrained factors in the disposal of medical dispute caused by nosocomial infection and try to find out the method to solve the problem. METHODS The several restrained factors in the disposal of medical dispute about nosocomial infection were enumerated and analyzed. RESULTS There are several restrained factors in the disposal of medical dispute about nosocomial infection according to law. First, nosocomial infection can not be died out, and medical dispute about nosocomial infection will exist for ever as a result of the specialty of supply of medical service. Secondly, current legal system construction of nosocomial infection management in our country is in the stage of being established and consummated step by step. Determinant criteria of medical negligence behavior are not perfect. Feasibility of part of the actual rules and standard in nosocomial infection is not good. Thirdly, collecting evidence is very difficult in some medical dispute caused by nosocomial infection . It is restricted by hospital condition, medical cost and medical documents. Because of the restrained factors mentioned above, when nosocomial infection occurs, medical workers concerned can not find or confirm the reason of infection in most cases. Then hospital has to compensate patients for loss in order to make concessions to avoid trouble. CONCLUSIONS We make following suggestions for the status. First, we should strengthen legal system construction about nosocomial infection, and safeguard both of hospital and patients′ interests . Secondly, insurance system of medical risk should be perfected. Thirdly, medical workers should abide by rules of operation. Fourthly, we can not hide the truth when nosocomial infection occurs. Fifthly, we must fulfil the "attention duty" in order to reduce medical dispute.
9.Investigation and analysis of one year survival rate and life quality of patients with non-small cell lung cancer treated by different arms
Zehui SUN ; Zelin SUN ; Yan ZHANG ; Xiaoyuan QI
Clinical Medicine of China 2017;33(2):145-149
Objective To investigate one year survival rate and life quality of patients with non-small cell lung cancer(NSCLC)treated by different arms.Methods One hundred and seventy-nine cases NSCLC patients from January 2013 to December 2014 were selected from the Third Hospital of Tanshan and followed-up,including 57 cases with surgical treatment,70 cases with the use of Navelbine plus cisplatin,52 cases with dendritic cells(DC)and cytokine induced killer cells(CIK)immune based therapy(DC/CIK)treatment.After one year period of radiotherapy and chemotherapy,the SF-36 questionnaire was used to investigate the quality of life of the surviving patients,and the quality of life was assessed from three aspects of the physiological,psychological and social functions.To quantify the quality of life score,the 100 percentage grading system was adopted,logistic regression analysis was used to adjust the influence of age and gender on survival rate,and the data were analyzed by SAS 9.2 statistical software package.Results One hundred and seventy-nine subjects were included in this study,by the end of follow-up on December 2015,there were 119 cases survived,the survival rate was 66.5%(119/179).Survival rate of surgical operation group,DC/CIK group and chemotherapy group orderly decreased(82.5%(47/57),76.9%(40/52)and 45.7%(32/70),P<0.01).After adjusting age and gender impact,multiple logistic regression model showed that DC/CIK group survival rate was 3.96 times higher than the pure chemotherapy group(95%CI=1.78-8.80),surgical operation group was 5.58 times higher than simple chemotherapy group(95%CI=2.44-12.79).There were no significant differences between DC/CIK group and surgical operation group on physical disease,health status,emotional intelligence,mental health and social function,no significant difference(P>0.05),but the chemotherapy group was lower(P<0.05);physiological function in the chemotherapy group,operation group and DC/CIK group showed an increasing trend(P<0.05).Conclusion The one year survival rate of NSCLC patients treated by different arms is 66.5%,and the life quality of patients with biological immune therapy method is better.
10.New development trends of LibQual+and its substantial evidence studies in foreign libraries
Shixia YAN ; Mingyou TAN ; Hui LIU ; Xiaoyuan YUAN
Chinese Journal of Medical Library and Information Science 2015;24(12):19-21
Described in this paper are the new development trends of LibQual+in foreign libraries, such as its modified analysis techniques, its perfected analysis methods, integrated LibQual+and other evaluation tools, further application of LibQual+evaluation analysis results.The successful application of LibQual+data analysis in University of California and University of York is a good inspiration to the domestic libraries.