1.Comparison of therapeutic effects of anatomic plate and Liss plate implantation for treating complex fractures of tibial plateau
Taibao XIA ; Huilin YANG ; Xiaoyu ZHU ; Chao WEI
Chinese Journal of Tissue Engineering Research 2007;0(43):-
0.05). In the anatomic plate group,2 cases developed loose of internal fixation,1 case of nail withdraw,without breakage,1 case of knee joint stiffness,1 case of traumatic arthritis in the knee joint. In the limited invasive stabilization system group,1 case affected traumatic arthritis in the knee joint. CONCLUSION:The therapeutic effects of anatomic plate and limited invasive stabilization system were similar in the treatment of complex tibial plateau fractures. Fixation materials should be selected according to the state of injury,bone conditions and economic status.
2.Effect of low-dose cefuroxime combined with dexamethasone on postoperative urinary tract infection and quality of life in cervical cancer patients
Xia YU ; Xiaoyu WANG ; Lin CHEN ; Ruanmin ZOU
Chinese Journal of Biochemical Pharmaceutics 2016;36(12):75-77
Objective To investigate the effect of low-dose of cefuroxime combined with dexamethasone on postoperative urinary tract infection and quality of life in cervical cancer.Methods 90 cases of cervical cancer patients from July 2015 to July 2016 in the first affiliated hospital of wenzhou medical university were selected and divided into two groups,44 patients in control group received cefuroxime sodium 1.5 g and metronidazole 0.5 g biw in five days,furacilin 250 mL bladder irrigation biw after five days,and fourteenth days out of indwelling catheter.46 cases in the experiment group received more with cefuroxime 125 mg and dexamethasone 0.75 mg oral,and two groups were treated for 14 days.Results After treatment,the incidence rate of urinary tract infection rate,the first urination time>three hours and residual urine ≥100 mL in the experiment group were lower than the control group (P<0.05);the total effective rate of the experiment group was significantly higher than the control group (P <0.05);the scores of physical function,physical life, mental health and social adaptation in the experiment group were significantly higher than the control group ( P <0.05 ) . Conclusion Low dose cefuroxime combined with dexamethasone have better prevention effect on urinary tract infection after cervical cancer operation , can significantly improve the quality of life of patients and treatment efficiency.
3.Endovascular repair vs conservative therapy for the treatment of acute type B aortic dissection
Fengyi WANG ; Jian ZHANG ; Qian XIA ; Yanshuo HAN ; Zhimin LIU ; Xiaoyu ZHANG ; Yu LUN ; Xiaoyu WU ; Shijie XIN ; Zhiquan DUAN
Chinese Journal of General Surgery 2012;(12):988-991
Objectives To compare endovascular aortic repair (EVR) and medical therapy for acute type B aortic dissection (AD) in terms of treatment results.Methods From January 2004 to October 2010 116 cases were collected and were divided into two groups,with treatment of EVR (n =60)and medical therapy (n = 56).Treatment outcomes were assessed.Results Clinical manifestations of AD are complex and variable,with the most common symptom being pain on chest and back (74.1%).CTA is the most valuable method in confirming the diagnosis of aortic dissection.In conservative group of 56 patients admitted to hospital,30-day mortality rate was 16.1%.In EVR group of 60 patients with grafts successfully released,the 30-day mortality was 1.7%.There is significant difference between the two groups on mortality rate during 30-day(P <0.05).Follow-up rate in conservative group and the EVR group was 71.4% and 86.7%,with average follow-up time of (38 ± 16) months and (35 ± 14) months.The 5-year survival rates were 87.5% and 88.5% respectively in conservative group and EVR group (P > 0.05).Conclusions EVR is considered to be the first choice for acute Stanford type B dissection.EVR can improve patients' 30-day survival,though long term result is comparable with that of conservative treatment.
4.Studying and practicing of ultrasound anatomy teaching sample of fetus heart with complex abnormity
Hongmei XIA ; Bing REN ; Xiaosong LI ; Liwen TAN ; Yan JIANG ; Xiaoyu LI ; Yunhua GAO
Chinese Journal of Ultrasonography 2011;20(10):875-878
ObjectiveTo make ultrasound anatomy teaching samples of odynopoeia fetus heart with complex abnormity consistent with echocardiographic view,and utilize them in echo teaching.MethodsTen odynopoeia foetus hearts were cutted comparing to different echocardiographic imaging respectively.Results Dissections of fetus heart were obtained including 5 cases of single cardiac ventricle(2 case with interruption of aortic arch),4 cases of double outlet of right ventricular,and 1 case of hypoplastic left heart syndrome with serious coarctation of the aorta.The apical long axis view,the three blood vessel view,as well as the long axis view of the aortic arch were typical views of ultrasound diagnosis and teaching.ConclusionsIt is profit to raise and accurate rate of fetus echocardiography diagnosis by studying dissection of fetus heart anatomic structure with complex abnormity,which would make ultrasound imaging visualization.
5.Surgical and interventional management of splenic artery aneurysms
Zhimin LIU ; Jian ZHANG ; Qian XIA ; Yansuo HAN ; Xiaoyu ZHANG ; Fengyi WANG ; Zhiquan DUAN ; Shijie XIN
Chinese Journal of General Surgery 2012;27(2):134-136
Objective To assess the treatment of splenic artery aneurysms (SAA) and prognosis.Methods Clinical data of 18 SAA patients treated in our hospital from 1999 to 2011 were retrospectively analyzed. Results There were 18 patients diagnosed as SAA,including 7 males and 11 females.The average age was 53.8 ± 7.3 years.8 patients were asymptomatic found by routine physical examination,7 patients complained upper left abdominal pain,3 cases suffered from aneurysm rupture. Diagnosis was established by three-dimensional computed tomography angiography (3DCTA) in 14,Digital subtraction angiography (DSA) in 3 and magnetic resonance angiography (MRA) in 1 patient.Three patients with ruptured splenic artery aneurysm underwent emergent operations,11 patients underwent elective surgery or interventional therapy.Surgical procedures included aneurysmectomy and splenectomy in 4 patients,distal pancreatectomy in 5 cases; aneurysmectomy and splenic artery ligation in one patient; and aneurysmectomy with splenectomy and colon resection in 1 case.Interventional embolization by coils of the splenic aneurysm in 3 patients.The remaining 4 being asymptomatic and with tumor diameter less than 2 cm were put on a close follow-up.There was no perioperative mortality.Two were lost to follow-up.16 cases were followed-up for averaging 3.2 years. 1 patient died of cerebral hemorrhage after four years. Conclusions Splenic artery aneurysms was a rare disease and with usually occult symptoms,but rupture can leads to abdominal apoplexy.Open surgery and minimally invasive endovascular treatment is effective and offers a good prognosis.
6.Relationship between DNA ploidy heterogeneity and clinical biological behavior on patients with malignant tumors
Xinyi XIA ; Yongming WU ; Lianjun PAN ; Baofang JIN ; Yufeng HUANG ; Xiaoyu WU
Journal of Medical Postgraduates 2003;0(03):-
Objective:To explore the relationship between DNA ploidy heterogeneity and clinical biological behavior on patients with malignant tumor.Methods:The DNA ploidy heterogeneity of tumor tissue was measured in 163 patients with malignant tumors by flow cytometry.The relations were analyzed between DNA ploidy heterogeneity and clinical stage,pathological grade,metastasis rate of patients with malignant tumors.Results:The rates of DNA ploidy heterogeneity were significantly different in different tumors.The rates of heterogeneity raised with increase of clinical stage and pathological grade(P
7.Expression and clinical significance of protein disulfide-isomerase A3 in a rabbit model of spinal cord ischemia/reperfusion injury
Chunxu LI ; Shanyong ZHANG ; Zhiping QI ; Peng XIA ; Su PAN ; Chunfang ZAN ; Xiaoyu YANG
Chinese Journal of Tissue Engineering Research 2017;21(24):3845-3850
BACKGROUND:At present, spinal cord ischemia/reperfusion injury is considered as the main reason for secondary paralysis after spinal decompression, and to control the levels of stress-related proteins and excitatory amino acids plays an important role in the treatment of spinal cord ischemia/reperfusion injury. OBJECTIVE:To investigate the expression level of protein disulfide-isomerase A3 (PDIA3) after spinal cord ischemia/reperfusion injury in rabbits. METHODS:Thirty-six New Zealand white rabbits were enrolled, the models of spinal cord ischemia/reperfusion injury were established using Zivin's method, and were then randomized into six groups (n=6 per group). The rabbit abdominal aorta in control group was exposed without vascular occlusion and then the abdominal cavity was closed 30 minutes later. In experimental groups, the abdominal aorta was blocked for 30 minutes, followed by 0, 6, 12, 24 and 48 hours of reperfusion, and then the abdominal cavity was closed. The neurological function was evaluated with a modified Tarlov score. The L3-5lumbar vertebrae were removed, and PDIA3 was screened by two-dimensional fluorescence differential gel electrophoresis combined with mass spectrometry, and then its temporal and spatial changes in the spinal cord were detected by western blot assay and immunohistochemistry. RESULTS AND CONCLUSION:The function of hind limbs was improved in all the experimental groups after spinal cord ischemia/reperfusion injury, and the modified Tarlov scores reached the peak at 24 hours after schemia/reperfusion injury, and decreased slightly at 48 hours. The expression of PDIA3 in the control group showed clear imprinting, which was slightly strengthened at 0 hour, became more strengthened at 6-12 hours, significantly reduced to the minimum level at 24 hours, and returned to the level of 6-12 hours at 48 hours after ischemia/reperfusion. Immunohistochemical results showed that there was visible PDIA3 in the cytoplasm of neurons, and the expression level in the interneurons was significantly higher than that in the motor neurons. These results suggest that upregulated PDIA3 appears in the development and progression of spinal cord ischemia/reperfusion injury, indicating that PDIA3 is closely related to spinal cord ischemia/reperfusion injury, which can be used as a new diagnosis and treatment target.
8.Experiment research on two-stage dry-fed entrained flow coal gasifier
Yongqiang REN ; Shisen XU ; Yue XU ; Juncang XIA ; Baomin WANG ; Xiaoyu LI
Journal of Pharmaceutical Analysis 2007;19(2):138-142
The process flow and the main devices of a new two-stage dry-fed coal gasification pilot plant with a throughout of 36 t/d are introduced in this paper. For comparison with the traditional one-stage gasifiers, the influences of the coal feed ratio between two stages on the performance of the gasifier are detailedly studied by a series of experiments. The results reveal that the two-stage gasification decreases the temperature of the syngas at the outlet of the gasifier, simplifies the gasification process, and reduces the size of the syngas cooler. Moreover, the cold gas efficiency of the gasifier can be improved by using the two-stage gasification. In our experiments, the efficiency is about 3%-6% higher than the existing one-stage gasifiers.
9.Comparative Study on Water Soluble Extract and Total Flavonoid Content between Jinzhen Suanzao Teabag and Decoction
Ting WANG ; Weining SUN ; Yong CUI ; Xiaoyun FU ; Xiaoyu LUO ; Jun WAN ; Xia ZHOU
China Pharmacy 2016;27(25):3542-3544
OBJECTIVE:To compare the quality control index between Jinzhen Suanzao teabag and decoction,and explore the alternative supplement of teabag to decoction. METHODS:The test sample solutions of Jinzhen Suanzao teabag and decoction were prepared by hot-maceration method and water-decoction method. The contents of water soluble extract and total flavonoids were de-termined and compared between 2 kinds of preparation. The leaching rates of teabag were investigated at different soak time(0,5, 10,15,20,25,30 min) to optimize soaking time. RESULTS:The average content of water soluble extract were 50.56% and 44.45%(P<0.05) respectively for the teabag and decoction. The total flavonoids content were 0.64 mg/g and 0.69 mg/g (P<0.05). The dissolution amount of teabag were increasing and leaching rate increased within first 20 min,and reached balance gradu-ally 25 min later. CONCLUSIONS:According to the convenience of use and results of each index,the difference in quality control index is not great between 2 kinds of preparation. Teabag can be as the supplement of decoction.
10.Effect of αⅡb Ala477Pro(A446P) mutation of the platelet glycoprotein on the expression of αⅡbβ3 complex
Xiaoyu YUAN ; Fangping CHEN ; Kun XIA ; Gan FU ; Zaifu JIAN ; Qinzhi JIE ; Guangping WANG
Journal of Central South University(Medical Sciences) 2009;34(8):712-717
ly reduces the expression of αⅡbβ3 complex on the membrane. This mutation may interfere the formation of αⅡbβ3 complex or impair the proper conformation of αⅡb subunit.