1.Evaluation of the application effect of foreseeable nursing and evidence-based nursing in anesthesia patients in the operation room
Chinese Journal of Practical Nursing 2012;28(25):46-48
Objective To discuss an effective nursing mode for operation room anesthesia.Methods 122 cases of patients with local anesthesia:in our hospital from January to December 2011 were divided into the nursing group and the control group with 61 cases in each group.They were given foreseeable nursing and evidence-based nursing respectively.The quality of nursing care,postoperative cognitive function and life quality were evaluated by self-made patient satisfaction questionnaire.Results The satisfactory degree of patients in the nursing group was 91.80%,compared with the control group of 88.52%,the result showed no significant difference.Each factor of life quality demonstrated no evident difference between two groups before treatment,but after treatment,the scores of emotional function and cognitive function were higher,while the score of somatic function was lower in the nursing group compared with those in the control group.Conclusions If the two methods of nursing can be combined in anesthetized patients in operation room,it can be of great importance to decrease the patients fear and improve the quality of life.
2.Effect of genistein on rat femoral bone metabolic activity in vitro.
Jian ZHOU ; Baofeng GE ; Keming CHEN ; Xiaoni MA ; Kui CHENG ; Xiaoyu GUO ; Xiang Lü
Acta Pharmaceutica Sinica 2013;48(6):960-4
This study is to investigate effects of genistein on rat femoral bone metabolic in vitro. Rat femoral tissues was isolated and randomly divided into two groups including control group and genistein (1 x 10(-5) mol x(-1)) group. Determinations of alkaline phosphatase (ALP) activity, calcium content and osteoprotegerin (OPG), type I-collagen (Collagen-I), RANKL, Runx-2 and bone morphogenetic protein (BMP-2) mRNA expression were done by real-time PCR. The results showed that 1 x 10(-5) mol x L(-1) genistein could increase the activity of ALP and contents of Ca, regulate bone metabolism activity of OPG, RANKL, BMP-2, Collagen-I and Runx-2 mRNA expression level. Genistein can significantly modulate bone metabolism related gene expression level of rat femoral tissue in vitro, and can increase calcium content and the activity of ALP.
3.Efficacy and safety of endoscopic colorectal polypectomy with high-frequency electrotome
Caifei SHEN ; Kui ZHAO ; Liming WANG ; Xiaoyu WU ; Haiyang JIANG ; Yaqin ZHAO ; Shuang MA ; Xiaobin SUN
Chinese Journal of Digestive Endoscopy 2021;38(6):475-478
Data of 643 patients who underwent endoscopic polypectomy with high-frequency electrotome in 6 hospitals of Sichuan Province between June 2020 and September 2020 were summarized. The rate of complete polypectomy and the incidence of delayed post-polypectomy bleeding (DPPB) and perforation were analyzed. DPPB occurred in 18 cases (2.80%) and postoperative perforation occurred in 1 case (0.16%). All of the 1 828 polyps were completely resected (100.0%). Univariate analysis showed that polyps′ diameter≥10 mm, long peduncle or laterally spreading tumor (LST), adenomatous polyp, endoscopic mucosal resection, mixed cutting mode 1 of electrocoagulation were significantly correlated with DPPB( P<0.05). Multivariate Logistic regression analysis revealed that polyp diameter≥10 mm ( P=0.001, OR=3.575, 95% CI: 1.175-9.955), morphology of long peduncle or LST ( P=0.004, OR=2.981, 95% CI: 1.233-14.858) were independent risk factors for DPPB. Endoscopic colorectal polypectomy with high-frequency electrotome is effective and safe. Polyps′ diameter≥10 mm, polyps with long pedicle or LST are the risk factors for DPPB.