Objective To analyze the correlation between clinical mental personality,coping style,social support and depression,anxiety for patients with chronic hepatitis B,and their treatment strategies.Methods A total of 66 patients with chronic hepatitis B (CHB group) and 72 normal people (control group) were investigated by the questionnaire,such as the demographic history questionnaire,Eysenck Personality Questionnaire (EPQ),Trait Coping Style Questionnaire (TCSQ),Perceived Social Support Scale (PSSS),Hamilton Depression Scale (HAMD),Hamilton Anxiety Scale (HAMD) were assessed.Results The HAMD score and HAMA score of hepatitis B group were significantly higher than that of the control group.Pearson correlation analysis showed that depressive symptoms was negatively correlated with positive coping,family support,extroversion,and was positively correlated with neuroticism.Multiple linear regression analysis showed family support,active coping,neuroticism and psychosis were all included in the regression equation and can predict depressive symptoms (3 values,0.002,0.003,0.004,0.022,respectively).Neuroticism,positive responded to the two independent variables (β values,0.003,0.011,respectively) into the regression equation,and can predict anxiety symptoms.Conclusion The patients with chronic hepatitis B were more prone to suffer from depression and anxiety than normal people,depressive symptoms are closely related to the neuroticism and neuroticism.The anxiety symptoms are related to neuroticism.The neurotic personality traits,lack of positive coping strategies and out-of-home support may lead to depression and anxiety.Depression and anxiety symptoms can be avoided by improving the patient's personality characteristics,and actively responding and enhancing the social support system outside the home soas to reduce depression,anxiety symptoms in patients with hepatitis B.

Objective To analyze the correlation between clinical mental personality,coping style,social support and depression,anxiety for patients with chronic hepatitis B,and their treatment strategies.Methods A total of 66 patients with chronic hepatitis B (CHB group) and 72 normal people (control group) were investigated by the questionnaire,such as the demographic history questionnaire,Eysenck Personality Questionnaire (EPQ),Trait Coping Style Questionnaire (TCSQ),Perceived Social Support Scale (PSSS),Hamilton Depression Scale (HAMD),Hamilton Anxiety Scale (HAMD) were assessed.Results The HAMD score and HAMA score of hepatitis B group were significantly higher than that of the control group.Pearson correlation analysis showed that depressive symptoms was negatively correlated with positive coping,family support,extroversion,and was positively correlated with neuroticism.Multiple linear regression analysis showed family support,active coping,neuroticism and psychosis were all included in the regression equation and can predict depressive symptoms (3 values,0.002,0.003,0.004,0.022,respectively).Neuroticism,positive responded to the two independent variables (β values,0.003,0.011,respectively) into the regression equation,and can predict anxiety symptoms.Conclusion The patients with chronic hepatitis B were more prone to suffer from depression and anxiety than normal people,depressive symptoms are closely related to the neuroticism and neuroticism.The anxiety symptoms are related to neuroticism.The neurotic personality traits,lack of positive coping strategies and out-of-home support may lead to depression and anxiety.Depression and anxiety symptoms can be avoided by improving the patient's personality characteristics,and actively responding and enhancing the social support system outside the home soas to reduce depression,anxiety symptoms in patients with hepatitis B.

Objective: To evaluate the efficacy of cognitive-behavioral therapy (CBT) combined with mirtazapine for patients with functional dyspepsia (FD). Methods: Totally 121 patients with FD who met Rome Ⅳ diagnostic criteria in clinic of clinical psychiatry of a general hospital were collected.They were randomly divided into combined treatment group(n=61) and single drug group(n=60). The treatment period was 8 weeks.All patients with FD were given mirtazapine.The combined treatment group received 8 times systemic CBT treatments at the same time.Symptom checklist-90 (SCL-90) and gastrointestinal integral scale (GIS) were evaluated in all patients before and after 8-week intervention. Results: After 8 weeks of intervention, the total score of SCL-90 scale, somatization, compulsion, depression, paranoia and other factors in the combined treatment group were lower than those in the single group(130.26±36.18 vs 147.95±45.55, 1.34±0.44 vs 1.51±0.5, 1.66±0.50 vs 1.90±0.66, 1.47±0.52 vs 1.69±0.63, 1.48±0.49 vs 1.70±0.61, 1.47±0.50 vs 1.73±0.68, respectively)(all P<0.05). After 8 weeks of intervention, the total score of the GIS scale in the combined treatment group (6.77±5.05 vs 9.49±5.24), vomiting (0.57±0.77 vs 0.88±0.91), spastic upper abdominal pain (0.43±0.74 vs 0.90±1.08) and post-sternal discomfort (0.57±0.89 vs 1.05±1.19) were significantly lower than that of the simple drug group after intervention(6.77±5.05 vs 9.49±5.24, 0.57±0.77 vs 0.88 ±0.91, 0.43±0.74 vs 0.90±1.08 and 0.57±0.89 vs 1.05±1.19, respectively), and the differences were statistically significant (all P<0.05). Conclusion CBT combined with mirtazapine in the treatment of FD is superior to drug therapy alone.CBT combined with mirtazapine can improve the emotional problems in the treatment of FD and further improving the digestive function.