ObjectiveTo determine the nature of the food poisoning event that has not gathered the reason. Methods The descriptive epidemiology and case of illness are used to conduct a contrastive study. The bacterium study, the serology examination and the HACCP hygiene investigation method will be adopted as well for investigation and analysis. ResultThe attack rate of poisoning is 6.67%, incubation period 1.5~6.5h, center position incubation period 4.5h and the dangerous ratio of the food roasted chicken legs (OR) is 28.33, which is connected with the poison. The examination result is that the food is infected by the Vibrio parahaemolyticas to mix the Aeromonas sobria. The HACCP investigation determines that the food is poisoned by the overlapping contamination between the utensil and the food, or the dissemination of the disease carried by the staff. ConclusionThis the food poisoning event is caused by the Vibrio parahaemolyticas to mix the Aeromonas sobria.

Objective To observe clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis.Methods 96 patients with chronic conjunctivitis from ophthalmology department from January 2015 to October 2016 were grouped two groups by draw method,each with 48 cases.The control group was treated with ofloxacin eye drops,and observation group was treated with Zhenzhumingmu eye drops combing with ofloxacin eye drops.Related indicators are analyzed in two groups.Results ①Effective rate of observation group was 87.50%,higher than control group with 66.67%(P<0.05).②Dry eye, eye itching, eye fatigue and foreign body sensation score of observation group were (1.01±0.24),(0.93±0.22),(0.85±0.18),(0.81±0.25)points,lower than control group(1.46±0.30),(1.39±0.25),(1.16±0.21),(1.22±0.29)(all P<0.05).③Eye discomfort proportion of observation group was 12.50%, higher than control group 8.33%,but the difference was not statistically significant.Conclusion Zhenzhumingmu eye drops has exact curative effect in treatment of chronic conjunctivitis,can improve the symptoms and has high security.

Objective To study the effect of dexmedetomidine combined with ketamine anesthesia on interventional therapy of children with congenital heart disease (CHD). Methods 40 cases of congenital heart disease were treated with catheter intervention from January 2013 to January 2017. The changes of pulmonary arterial pressure and the effect of anesthesia were compared before and after operation. Results 40 cases of children without surgical deaths, 36 cases of successful closure, the success rate of 90% of the operation, the patient after catheter intervention surgery after the results of the test were better than before and after treatment of children with pulmonary artery pressure (P<0.05), and the anesthesia effect was good in children. Conclusion The effect of dexmedetomidine combined with ketamine on the treatment of cardiac catheterization in children with congenital heart disease can achieve good results. The success rate of operation is high and safe, and it is highly reliable.

The weaning male Wistar rats were fed diets with 0.2, 2.0 and 5.0 ppm as Na2SeO4 respectively for 7 weeks. On each Se level, rats were divided into groups with or without supplementation of vitamin E and DL-methi-onine (VE-Met) and possible metabolic interactions of VE-Met to dietary Se at different levels in relation to the detoxification mechanism were ob- served. The results showed that only rats in unsupplemented, 5 ppm Se-diet group exhibited distinct toxic manifestations, and supplementation of VE-Met to this group gave effective protection against the toxic action. In the supplemented group Se content of blood, liver, kidneys and skeletal muscle of the experimental animals was decreased, while the excretory rate of urinary trimethylselenonium ion was increased to a level of 33% in contrast to 22% in the unsupplemented group (P

Objective To assess the value of two-dimentional strain/strain rate (2D-S/SR) imaging compared with endomyocardial biopsy (EMB) in detecting acute rejection (AR) reaction after heart transplantation (HT). Methods Twenty-five patients who required HT underwent echocardiography within 12 h after EMB. Ten patients of grade 0 AR were regarded as group A, 8 patients with grades Ⅰa-Ⅰb were considered as group B, 7 patients with grades ≥Ⅱa were considered as group C. Thirty age-matched normal controls were considered as group D. The longitudinal, radial and circumferential stain and strain rate of different ventricular wall in systolic were measured and compared among groups. Results Compared with the group D, longitudinal stain (LS) of basal-septum, circumferential strain rate (CSR) of ant-septum at the level of mitral valve, radial strain (RS) of all segments at the level of mitral valve reduced in groups A, B and C. Conclusion The RS of 2D-S/SR is an effective and sensitive technique for the detection of acute rejection, and longitudinal stain can be used as an early index of AR for grade ≥Ⅱ after HT.

Objective: To observe the clinical effect of depakine (sodium valproate) in the treatment of childhood epilepsy.　Methods:78 epileptic children were treated with either godilum valproate sustained-release tablets or syrups according to their ages, the control degree of the seizures were observed and reexamination of liver function and blood routine were carried at periodically.　Results: Of the 78 cases, 58 cases (74.4 percent) were completely controlled, 10 cases (12.8 percent) significantly improved, 5 cases (6.4 percent) improved, 5 cases (6.4 percent) remained the same. The total effective rate was 93.6 percent.　Conclusion: Depakine is a new broad-spectrum, easily used anti-epliepsy drug. Its efficacy is significant and there are different dosage forms to be selected and no significant adverse reactions. So depakine is the first selection in treating childhood epilepsy and suited for clinical application.

Objective To evaluate the diagnostic ability of dermoscopy in tiny pigmented basal cell carcinoma (BCC).Methods Fifty-eight patients with lesions measuring less than 5 mm in diameter and suspected for tiny pigmented basal cell carcinoma were enrolled in this study.The patients included 19 males and 39 females aging from 16 to 82 years.The disease course varied from 3 months to 25 years.The suspected lesions were examined by dermoscopy,then,two dermatologists independently made a diagnosis according to the findings on dermoscopy.Tissue specimens were also obtained from the suspected lesions for pathological diagnosis.The sensitivity,specificity and consistency with histopathology were calculated for dermoscopy in the diagnosis of tiny pigmented basal cell carcinoma.Results Of the 58 patients,36 were diagnosed with basal cell carcinoma according to pathological findings.Based on the dermoscopic features,41 cases were diagnosed as pigmented basal cell carcinoma by the dermatologist A,and 40 by the dermatologist B.The sensitivity,specificity,Youden index and Kappa value of dermoscopy were 97.22％,72.73％,69.95％ and 0.732 (P ＞ 0.05) respectively in the diagnosis of tiny pigmented basal cell carcinoma by the dermatologist A,97.22％,77.27％,74.49％ and 0.772 (P ＞ 0.05) respectively by the dermatologist B.Conclusion There is a high consistency between dermoscopy and histopathology in the diagnosis of tiny pigmented basal cell carcinoma.

Objective To assess the value of echocardiography in guiding surgical operation approach of ventricular septal defect (VSD). Methods A total of 200 patients with VSD underwent surgical repair. The type of VSD was determined with echocardiography before operation and the results were analyzed in comparison with operation approach. Results There was significant accordance in the type of VSD detected with echocardiography and the surgical findings, and the coincidence rate of 80.00%. The transatrial approach was chosen in patients with perimembranous VSD, subseptal cusp VSD and simple membranous;the anspulmonary approach was chosen in subarterial VSD, while transventricular approach was chosen in muscular VSD or VSD with large size. Combined approach was suitable in VSD complicated with intracardiac malformations. Conclusion The type of VSD determined with echocardiography plays a key role in the selection of operation approach, and is benefit to reducing complications.

Objective: To establish the quality standard for Fufang Dusheng ointments. Methods: Angelicae sinensis radix and Cinnamomi ramulus in Fufang Dusheng ointments were identified by TLC. Cinnamaldehyde was determined by HPLC. Results: The characteristic identification by TLC was distinct and highly specific. Cinnamaldehyde had the linear range of 5. 025-50. 255 μg·ml-1 (r=0. 999 9), and the average recovery was 98. 92% (RSD=1. 64%, n=9). Conclusion: The method is reliable, accurate and specific. It can be used in the quality control of Fufang Dusheng ointments.

Abstract Female stress urinary incontinence (SUI) is a major global public health problem, and its involuntary urinary leakage may seriously affect patients' quality of life. The pathophysiological changes in muscle, connective and nerve tissues induced by diabetes have been found to be strongly correlated with the development and progression of SUI. This review summarizes the association between diabetes and SUI in women and the underlying pathophysiological mechanisms, so as to provide insights into prevention of SUI among female patients with diabetes.