1.Pilot experience and thinking of long-term care insurance system in Panjin City
Journal of Shenyang Medical College 2024;26(1):68-71
Objective:To understand the pilot operation status of long-term care insurance system in Panjin City,and provide ideas and reference basis for improving the long-term care insurance system in Liaoning Province and the whole country.Methods:The protection content,fund raising,and treatment payment policies of long-term care insurance in Panjin City was systematically sorted out.And referring to other pilot cities combined with the actual situation in China,improvement suggestions were put forward.Result:After sorting and analyzing,it was found that the long-term care insurance system in Panjin City had a single financing channel,a small coverage of insurance coverage and insured objects,an unspecified payment service content,and an incomplete evaluation system.Conclusion:A long-term care special fund should be established,policy coverage should be expanded,and a scientific and reasonable evaluation system should be established.
2.Advances on the treatment of Fusobacterium nucleatum-promoted colorectal cancers using nanomaterials.
Hang WANG ; Xiaoxue HOU ; Jianfeng LIU ; Cuihong YANG
Chinese Journal of Biotechnology 2023;39(9):3670-3680
Fusobacterium nucleatum (Fn) is an oral anaerobic bacterium that has recently been found to colonize on the surface of colorectal cancer cells in humans, and its degree of enrichment is highly negatively correlated with the prognosis of tumor treatment. Numerous studies have shown that Fn is involved in the occurrence and development of colorectal cancer (CRC), and Fn interacts with multiple components in the tumor microenvironment to increase tumor resistance. In recent years, researchers have begun using nanomedicine to inhibit Fn's proliferation at the tumor site or directly target Fn to treat CRC. This review summarizes the mechanism of Fn in promoting CRC and the latest research progress on Fn-related CRC therapy using different nanomaterials. Finally, the applications perspective of nanomaterials in Fn-promoted CRC therapy was prospected.
Humans
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Colorectal Neoplasms/pathology*
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Fusobacterium nucleatum/genetics*
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Base Composition
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RNA, Ribosomal, 16S
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Phylogeny
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Sequence Analysis, DNA
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Tumor Microenvironment