1.Clinical value of super selective transcatheter arterial embolization for spontaneous rupture of hepatocellular carcinoma
Ge WANG ; Xiaoxia BI ; Xuemei LI
Chinese Journal of Primary Medicine and Pharmacy 2008;15(8):1235-1236
Objective To evaluate effects of transcatheter hepatic arterial embolization(TACE)on spoutaneoua rupture of hepatocellular carcinoma(SRHC).Methods Emergent hepatic arterial catheterization was performed in 38 cases of SRHC,using sponge gelatin,iodized oil and PVA tO embolize blooding arterial branch.Results Blooding was completely cortrolled by TACE in 35 eases,of which one patient died of severe hypohepatia and renal insufficiency 3 days later,and two patients died of misdiagnosis,35 patients remained to be alive after 3 months.33 patients remained to be alive after 6 months.28 patients remained to be alive after 12 months.Conclusion Arterial embolization is a good method for treating SRHC,especially to the patients which could not completdy removal the cancer,its eftect is superior to other surgical operation for hemostasia.
2.Application of Edaravone,Ozagrel sodium combined nursing intervention for patients with cerebral infarction in speech and limb rehabilitation
Xiaoxia GE ; Wenli SHI ; Yusufu ROUKEYANMU.
Chinese Journal of Biochemical Pharmaceutics 2017;37(9):163-165
Objective To investigate the clinical effect of Edaravone,Ozagrel sodium combined nursing intervention for patients with cerebral infarction in speech and limb rehabilitation. Methods 116 patients with cerebral infarction methods met inclusion criteria were randomly divided into control group (n=58) and study group (n=58). Two groups were given treatment with Edaravone andOzagrel sodium,the control group was given routine mode nursing, the study group was given early targeted rehabilitation nursing. Compare patient language, physical recovery and daily life recovery between control group and study group after nursing. Results Contrast group and the study group after the nursing intervention, rehabilitation effect of significant efficiency were 48.28% and 75.86%, the difference between groups was statistically significant (P<0.05);nursing before the implementation of 2 groups of patients with speech and limb function showed different degrees of impairment, nursing after the implementation of the 2 groups of patients with ABC score and Fugl-Meyer score were significantly increased, the difference between groups was statistically significant (P<0.05), and the patients in the study group ABC the scores of Fugl-Meyer and enhance the rate higher, the difference between groups was statistically significant (P< 0.05); the study group ADL Barthel index was significantly better than the control group, the rank sum test (Z=3.063, P=0.002 ) that has a statistically significant difference between the two groups. Conclusion Edaravone,Ozagrel sodium combined rehabilitation nursing intervention can effectively improve the speech and limb function recovery, and improve the quality of life of patients, nursing satisfaction, is worthy of clinical application.
3.The clinical value of combination of transcatheter superselective intra-arterial chemotherapy in the combined treatment of advanced nasopharyngeal carcinoma
Ge WANG ; Xiaoxia BI ; Xiaopeng ZHONG
Cancer Research and Clinic 2006;0(10):-
Objective To evaluate the clinical value of selective arterial chemotherapy after radiotherapy for advanced nasopharyngeal carcinoma (stageⅢ,Ⅳa). Methods Sixty patients with advanced nasopharyngeal carcinoma were randomized to receive either combined elective arterial chemotherapy and radiotherapy (IACT group, 30 patients) or combined general intravenous chemotherapy and radiotherapy(IVCTgroup, 30 patients). Four weeks after radiotherapy, the effect of two methods was compared. Results The efficiency rate and the 1-year local disease control rate were 93.33 %, 92.86 % in IACT and 70.00 %, 71.43 % in IVCT, respectively. There were outstanding differences between the two groups(P
4.Design of the temperature control system for the thermostatic medical infusion pump.
Xuefei HAN ; Rongguo YAN ; Jie DING ; Bin GE ; Xiaoxia LI
Journal of Biomedical Engineering 2014;31(6):1294-1309
In surgery operations, wound should be cleaned with warm sterilized saline solution. In order to reach rapidly warming the washing solution from the room temperature during the surgery, we designed a thermostatic medical infusion pump. The present paper mainly presents researches on the two temperature control methods in the standby mode and in the flushing mode of the system. In the standby mode, the traditional proportional-integral-derivative (PID) control algorithm was adopted. In the flushing mode, dynamic characteristics of the system was changed in real time, which made the thermostatic control process more complex, and the fitted control function combined with the PID control algorithm was adopted in this mode. The temperature control parameters were adjusted in real time according to the initial temperature and the flow rate of the washing solution to obtain a constant temperature of the washing solution, no matter how the initial temperature and the flow rate are changed. The experiment results showed that this kind of control system performed well with a high accuracy.
Algorithms
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Equipment Design
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Infusion Pumps
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Sodium Chloride
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Solutions
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Temperature
5.Comparative study of therapeutic effects of DF and GEM alone regimens of concomitant radiochemotherapy for stage Ⅲ~Ⅳa nasopharyngeal carcinoma
Li BAI ; Xiaoxia BI ; Yuhong LAN ; Wenhui ZOU ; Ge WANG
Chinese Journal of Primary Medicine and Pharmacy 2006;0(06):-
0.05).The major toxicity and side effects were bone marrow inhibition,gastrointestinal reaction and mucosal reaction.The difference of hematologic toxicity and gastrointestinal between the two groups was statistically significant(P0.05).The GEM group could be well tolerated for the concurrent chemoradiotherap of patients with stage Ⅲ~Ⅳa nasopharyngeal carcinoma(NPC).
6.Synthetic Treatment of the Ⅲa Stage of Non-small-cell Lung Cancer byCombining Chemotherapy of Bronchus Artery Instillation and Radiotherapy of Line Accelerator
Ge WANG ; Xiaoxia BI ; Xilong ZHANG ; Jiming CHEN
Journal of Practical Radiology 1991;0(03):-
Objective To make an inquiry into the feasibility and clinical effect of treating the Ⅲa stage of non-small-cell lung cancer(NSCLC)by combining chemotherapy of bronchus artery instillation and radiotherapy of line accelerator.Methods 76 cases of patients with NSCLC were randomly divided into two groups of A and B.Chemotherapy of bronchus artery instillation (BAI) was exerted twice to group A first,then radiotherapy (RT) of line accelerator was followed one~two weeks later after completing the second BAI;Group B was simply performed two times of BAI (contrast group).Results Clinical curative effect of group A (BAI+RT) and group B (BAI) were respectively 89.47% and 60.53% (?
7.Sphingosine 1-phosphate prolongs action potential duration and inhibits voltage-dependent potassium current in guinea-pig ventricular myocytes
Jingyan GE ; Wenjie ZHANG ; Xia CHEN ; Xiaoxia SUN ; Ming ZHAO ; Chunyan ZHAO ; Guogan ZHONG
Basic & Clinical Medicine 2006;0(01):-
Objective To investigate the effect and mechanism of sphingosine 1-phosphate(S1P)on action potential(AP)and voltage-dependent potassium current(KV)in isolated guinea pig ventricular myocytes.Methods The ventricular myocytes were isolated by using Langendorff perfusion method.The AP and KV were recorded by whole cell patch-clamp recording technique.Results S1P prolonged the 50% and 90% action potential duration(APD50 and APD90)and decreased KV which were blocked by pertussis toxin(PTX)or Calphostin C.Conclusion S1P decreased KV in a PKC pathway and prolonged action potential duration in guinea-pig ventricular myocytes.
8.Real-time three dimensional echocardiography in evaluation of left ventricular volume and ejection fraction in patients with aneurysm combined with myocardial infarction
Yong XU ; Guang ZHI ; Tingshu YANG ; Luyue GE ; Qi SUN ; Xiaoxia WU
Academic Journal of Second Military Medical University 1985;0(06):-
Objective:To assess the feasibility and accuracy of real-time three dimensional echocardiography(RT-3DE) in quantitative evaluation of left ventricular(LV) volume and ejection fraction(EF) in patients with ventricular aneurysm and myocardial infarction.Methods: Twenty-three patients with left ventricular aneurysm combined with myocardial infarction were examined by RT-3DE,two dimensional echocardiography Simpson's method,and M-mode Teichholz method separately.The following parameters: left ventricular end diastolic volume(LVEDV),end systolic volume(ESV),stroke volume(SV) and EF were obtained by each method and the results were compared with those obtained by left ventriculography(LVG).Results: The values of LVEDV,LVESV,SV,and EF determined by RT-3DE showed good correlations with those determined by LVG(r=0.92,0.90,0.88,and 0.91,respectively;P(0.05).) The values of LVEDV,LVESV,SV,and EF determined by Simpson's method also showed good correlations with those determined by LVG(r=0.85,0.87,0.86,0.91,respectively;P
9.Cultivation of doctor-patient communication ability for general practitioners based on iceberg theory
Xiayuan ZHU ; Hao WU ; Caiying GE ; Xiaoxia LI ; Zhili LI ; Min KONG ; Xiumei LIU ; Junxing LIU
Chinese Journal of General Practitioners 2017;16(9):737-739
An iceberg model for better understanding the patients was developed.In this model the seeking for consultation is visible part of illness behavior,but the thoughts,concerns and expectations toward his or her illness are the hidden parts.Through detailed history taking,using appropriate language skill (Leichester Assessment Package) and nonverbal communication skill (space distance,eye contact,listening,pronunciation,appropriate silence),physicians can acquaint comprehensive knowledge about the hidden thoughts,concern and expectation of patients about their illness.This model would help general practitioners to raise communication and consultation ability and skills in their practice.
10.Inhibitory Effects ofQi-Zhu Granules on Early Proteinuria in Diabetic Nephropathy Rats with Syndrome ofQi-yin Deficiency and Phlegm Blocking Collaterals
Xiaohua HONG ; Jianxun REN ; Yanghui WANG ; Long JIN ; Bin YANG ; Xiaoxia DONG ; Wei ZHANG ; Zhengyan GE ; Hongkun LI ; Jianxun LIU
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(7):1392-1397
ThisstudywasaimedtoobservetheinhibitoryeffectsofQi-Zhu (QZ)granulesonearlyproteinuria in diabetic nephropathy rats with syndrome of qi-yin deficiency and phlegm blocking collaterals. A total of 44 rats were randomly divided into the blank group, model group, Huang-Kui capsule group, QZ granules group. The rat model of diabetic nephropathy with syndrome of qi-yin deficiency and phlegm blocking collaterals was induced by the combination of unilateral renal artery ligation, diet of high-calorie and high cholesterol, and intraperitoneal injection of low-dose streptozotocin. The medication was given for 8 weeks. The concentrations of protein and creatinine in urine were observed on the 4th week. The blood glucose, blood lipids, liver function and renal pathological changes were observed at the end of the experiment. The results showed that compared with the model group, QZ granules can obvious suppress early proteinuria in diabetic nephropathy, promote creatinine excretion, regulate blood lipid metabolism, protect liver function and improve renal pathological changes. It was concluded that QZ granules had independent inhibition effect on early proteinuria in diabetic nephropathy rats with syndrome of qi-yin deficiency and phlegm blocking collaterals. The effect was independent of lowing blood glucose. It represented the corresponding relation between the syndrome and efficacy in Chinese herb compounds.