Objective To evaluate the clinical outcome of microendoscopic surgery in treatment of lumbar spinal stenosis. Methods Twenty patients with lumbar spinal canal stenosis were treated with microendoscopic dis-cectomy by using the METRx microendoscopie spinal system. A fenestration of lamina, removal of ligamentum flavum and part of the facet were performed endoscopically,to obtain the complete decompression of dural sac and bi-lateral nerve roots. Clinical outcomes were evaluated with the modified functional scoring system. Results For thisgroup patients,the mean operation time was 112min,mean operative blood loss was 90ml,and mean duration of hos-pital-stay was 10.1 days. In the mean follow up of 9 months,15 cases were excellent,2 good and 3 fair based on the modified functional scoring system. Conclusion Microendoscopic spinal surgery is a safe, effective and ideal decom-pressive surgical method for lumbar spinal canal steneais.

[Objective]To discuss the perioperative management of thoracolumbar fractures fixed with latero-anterior screw-plate system.[Method]The entry point and direction of screw on 30 thoracic and lumbar vertebra specimens were marked based on the principle and demand of implantation of latero-anterior screw-plate system and were determined exactly by anatomic landmarks in order to make reference for operation.Sixty patients with thoracolumbar fractures were treated with anterior decompression,bone grafting and internal fixation from January 2000 to June 2007.Reference data such as the length of vertebral body screw and plate and the height of bracing gotten from the patients'X-ray and CT findings before operation were compared with practical data measured during operation.The entry point and the direction of screw were determined exactly by anatomic landmarks of thoraco lumbar vertebrae and were checked by X-ray during operation.[Result]The judgement of the entry point and the direction of screw was easy and accurate during operation and the reference data were in coincidence with practical data.The effects of operation were satisfactory.[Conclusion]The perioperative management is both scientific and practical.The surgical complications can be reduced in this way.

[Objective]To explore the mechanism of hip joint capsule contracture induced by intragluteal injection. [Method]Thirty young Chinese rabbits were divided into four groups of A(n=6),B(n=6),C(n=6) and D(n=12) at random.Rabbits in groups A,B and C were treated with deep intragluteal injection of penicillin dissolved in 2% benzyl alcohol(group A),2% benzyl alcohol(group B)and penicillin dissolved in physiologic saline(group C).Rabbits in group D were treated with immobilization of unilateral hip joint and deep intramuscular injection of physiologic saline on the homolateral buttock.Each rabbit was injected twice a day for 20 days.Specimens were obtained at 30,60 and 90 days after first injection and the evaluation of the functions of hind limbs was obtained at the same time.The thickness of hip joint capsules were measured with micrometer and sections of joint capsules were stained by Sirius red and were observed with microscope and polarization microscope.[Result]Capsules of hip joint in group A and B became thicker and contractural,and the change of joint capsules was reflected in the change of motion of hind limbs.Sections in groups A and B showed shrinked capsules with thick collagens in disordered arrangement;while there were no gluteus contracture and contracture of joint capsule in the other groups.[Conclusion]Deep intragluteal injection of penicillin dissolved in 2% benzyl alcohol or 2% benzyl alcohol into young rabbits can cause contracture of hip joints.The contracture of joint capsule is largely induced by tissue trauma and repair of joint capsules.The limited locomotion of hip joint induced by the contracture of gluteal muscle does not play an important role in the contracture of joint capsule.

Objective To investigate the application of hazard analysis and critical control point (HACCP) in the prevention and control of multi drug-resistant bacteria infection in the Department of Neurosurgery.Methods Following the principle and method of HACCP,we conducted a hazard analysis on the medical environment or medical care in the Department of Neurosurgery;the critical control points and critical limits were determined,and therefore,corresponding measures of monitoring and rectifying,and procedures of verification and record system were established.Results After the implementation of HACCP management system,the discovery rate of multi drug-resistant bacteria infection in the Department of Neurosurgery decreased from 3.12％ (January 2012 to June 2013) to 2.06％ (July 2013 to December 2014) (x2=3.921,P=0.048),the average hospitalization days shortened from (62.02±68.59) d to (48.49±38.09) d (t=1.105,P=0.272),and the average cost of hospitalization reducedfrom (104571.41±71 721.62) Yuanto (77257.20±45 810.14) Yuan (t=2.182,P=0.032).Conclusion HACCP is worth promoting in the prevention and control of multi drug-resistant bacteria infection in the Department of Neurosurgery.