1.Application of McKenzie technique in the treatment of cervical spondylotic radiculopathy
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(07):-
Objective To compare the effect of the McKenzie method and traditional manipulation in the treatment of patient with cervical spondylotic radiculopathy. Methods Seventy-two patients (42 women and 30 men with an average age of 42.60?13.73 years ) were randomly divided into 2 groups: an observation group and a control group. Both groups were given cervical traction, medium frequency electrotherapy and ultrasound therapy. In addition, the observation group was also treated with the McKenzie techniques, while the control group was treated by traditional manipulation. All the subjects were evaluated in terms of the clinical effect, VAS(Visual analog scale), McKenzie′s movement loss. The 1-year follow-up results were obtained. Results Both groups got a good therapeutic effect( the cure rate was 69% and 55.5%, respectively) and significant pain relief (P0.05). Range of motion of the cervical spine of the observation group was significantly improved after the treatment(P
2.Effect of serum containing total flavonoids from roots of Daphne genkwa on cell immunity in mice
Xiaowen GAO ; Weifa ZHENG ; Yecheng PENG
Chinese Traditional and Herbal Drugs 1994;0(05):-
Objective To establish HPLC method for assaying total flavonoids from the roots of Daphne genkwa(TFRD) in serum of mice and to elucidate the effect of mice serum containing TFRD on cell immunity in mice.Methods TFRD Concentration in serum was determined from the mice received single ig TFRD at certain time intervals using HPLC method.The effects of TFRD serum on lymphocyte proliferation,killing activities of NK and LAK cell,and phagocytic activity of macrophage were detected by MTT method.Results TFRD in serum reached its highest concentration in 20—30 min after ig admi-(nistration.) TFRD-containing serum significantly improved the proliferation of lymphocyte,enhanced the killing activities of NK and LAK cells,and enforced the phagocytic activity of macrophage.Conclusion(TFRD-)containing serum is an effective agents for enhancing cell immunity in mice.
3.Prognosis of Center of Gravity Excursion in Standing on Functional Outcome in Stroke Patients
Cuihua LIU ; Pande ZHANG ; Xiaowen PENG ; Zhoukai PI ; Jiehua YANG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(3):218-219
Objective To study the influence of center of gravity excursion in standing on function outcome of stroke patients.Methods46 stroke patients were assessed with static posturography in standing,Fugl-Meyer Balance Scale,Barthel Index and the time in hospital.The patients were divided into 2 groups according to posturography results:center of gravity was inclined to the normal side (normal group),center of gravity was inclined to the hemiplegia side (hemiplegia group).ResultsThe ability of balance,walking and activity of daily living(ADL)of the normal group patients were better than that of the hemiplegia group patients,and the in-hospital time was shorter (P<0.001).ConclusionThe center of gravity excursion in standing is highly correlated with functional outcome of stroke patients.
4.Serial studies on the human balance function. Part Ⅱ: the normal limits and influential factors of the static balance function of normal adults
Xiaowen PENG ; Pande ZHANG ; Zimao ZHANG ; Wenqing HUANG
Chinese Journal of Rehabilitation Theory and Practice 2005;11(8):644-646
ObjectiveTo explore the normal limits and influential factors of the static balance function of normal adults.Methods445 healthy volunteers (16~74 years old, 205 of male and 240 of female) were detected by static posturography while they were respectively in seat, double feet standing with eyes opened and closed, and single foot standing only with eyes opened. The normal reference value of all indicatrix were calculated.ResultsThe normal reference value of static balance function of normal adults, male, female and all age groups were calculated.ConclusionThe detection of static posturography can evaluate human balance function objectively, quantitatively and exactly. The determination of the normal limits of balance function will conduce to evaluate balance disturbance and diagnose correlated diseases.
5.Application of Ponseti method in patients older than 6 months with con-genital talipes equinovarus
Yanzhou WANG ; Xiaowen WANG ; Peng ZHANG ; Xingshan WANG
Journal of Peking University(Health Sciences) 2009;41(4):452-455
Objective:To evaluate the effectiveness of Ponseti method in the treatment of congenital talipes equinovarus (CTE) in children older than 6 months. Methods: Ponseti method was used to treat 157 cases (227 feet) of CTE in children older than 6 months. All cases were classified by age and by the degree of deformity severity. The age group classification was: (1) Ⅰ Group (6 months to 12 months),113 feet in 81 cases; (2) ⅡGroup (1 to 3 years old), 78 feet in 52 cases; (3) Ⅲ Group (>3 years old), 36 feet in 24 cases. The degree of deformity of CTE was evaluated with Pirani scoring system. The cases were classified into three groups according to the deformity degree : (1) Mild Group (scoring 1-2. 5) , 85 feet in 56 cases; (2) Moderate Group (scoring 3-4. 5) , 104 feet in 71 cases; (3) Severe Group (scoring 5-6) , 38 feet in 30 cases. A Pirani score of 0-0. 5 is regarded as an excellent result. For each group, we evaluated the number of casts used, the percentage of excellent result according to the Pirani score, and the percentage of percutaneous achillotenotomy. The result was compared among different groups. Results: The overall percentage of excellent result among all cases was 96.92%. A-mong the age groups, the percentage of excellence was not statistically different between Ⅰ Group and Ⅱ Group (P>0. 05). The percentage of excellence was lower in the Ⅲ group than the other groups (P> 0. 01). Among the groups classified by deformity degree, the percentage of excellence was the lowest in severe group (P<0. 05), and the difference between the mild group and moderate group was not statistically different (P>0. 05). The number of casts used among different groups were different (P<0. 01). Among different groups, the percentages of percutaneous achillotenotomy were significantly different (P<0. 01). 209 feet in 148 caseswere followed up for average time duration of 3 years and 11 months. Re-lapse was observed in 40 feet in 29 cases. The percentages of relapse were not statistically different among different groups (P>0. 05). Conclusion: Using Ponseti method to treat CTE for children older than 6 months can achieve excellent results in this study.
6.Effect of femoral intramedullary guides on prosthesis arrangement in total knee arthroplasty
Lexiang LI ; Feng XUE ; Xiaowen SHENG ; Yuqin PENG
Chinese Journal of Tissue Engineering Research 2016;20(4):481-485
BACKGROUND: The femoral intramedul ary guides in total knee arthroplasty require high precision, complex operation, it is very important for prosthesis and joint function to choose more precise positioning method and determine the correct needle point. OBJECTIVE: To study the effect of needle point position on prosthesis arrangement when applying different femoral intramedul ary guides methods in total knee arthroplasty. METHODS: Total y 80 patients who received the treatment of total knee arthroplasty in Changshu No.1 People’s Hospital from January 2012 to July 2015 were selected and divided into test and control groups according to random number table (n=40/group). The patients in the test group accepted CT scan for femoral intramedul ary guides. The theoretical position of femoral intramedul ary guides entry point was marked using radiographic parameters. In the control group, the traditional total knee arthroplasty technology was used to mark the entry point of femoral intramedul ary guides. The needle point position when applying different femoral intramedul ary guide methods was observed. The effect of femoral intramedul ary guides on prosthesis arrangement in total knee arthroplasty was discussed. RESULTS AND CONCLUSION: Compared with the control group, the distance from entry point to femoral anatomic line on positive and lateral X-ray film in the test group was shorter, femoral prosthesis lateral angle and physiological valgus angle were closer to the theoretical value, distance from intersection of femur axis and femoral condyle to block center was shorter; the differences were statistical y significant (P < 0.05). These results demonstrate that compared with the traditional two-dimensional intramedul ary positioning, the needle point position of three-dimensional CT scan stimulative positioning is more accurate. The location more concentrates on within intercondylar fossa 2-5 mm, more front of intercondylar fossa 3-10 mm, three-dimensional CT scan stimulative positioning is a reliable choice for femoral intramedul ary guides.
7.Construction of Hospital Service System Based on WeChat Public Platform
Pan PENG ; Jindong LV ; Li CHEN ; Xiaowen YANG
Journal of Medical Informatics 2015;(6):39-41
〔Abstract〕 Based on elaborating the application of WeChat public platform in various industries, the paper overviews the function and characteristics of WeChat public platform, taking Shanxi Provincial Peoplel's Hospital as an example, it introduces the application of We-Chat public platform in outpatient and inpatient departments, points out that WeChat service could be carried out in hospital in the futrue.
8.Total knee arthroplasty with Gemini MKII rotating-platform prosthesis
Qiang WANG ; Junying SUN ; Feng XUE ; Xiaowen SHENG ; Yuqin PENG
Chinese Journal of Tissue Engineering Research 2014;(13):2018-2023
BACKGROUND:Total knee arthroplasty mainly used fixed platform, but more and more movable platform was selected year by year in the clinic. Rotary platform theoretical y can apparently improve the curative effects, but it has not been verified in the clinic.
OBJECTIVE:To summarize the design characteristics and clinical results of Gemini MKII (Link, Germany) rotary platform.
METHODS:From January 2004 to January 2009, 108 patients (119 knees) including 31 males and 77 females were treated with total knee arthroplasty by using Gemini MKII system. There were 97 unilateral cases and 11 bilateral cases at the first stage of replacement. Preoperative diagnosis:1 case of hemophilic arthritis, 1 case of venereal Charcot’s disease, 8 cases of post-traumatic arthritis, 11 cases of rheumatoid arthritis, and 87 cases of degenerative osteoarthritis. The prosthesis was fixed with bone cement. None received patel ar replacement. RESULTS AND CONCLUSION:None experienced infection, femoral condyle fracture or nerve and vascular damage. Except bilateral replacement, the average operation time of unilateral replacement was (56±13) minutes. Average postoperative hemoglobin decreased (25±5) g/L. After replacement, hemoglobin maintained over 100 g/L in 83 patients (86%), without blood transfusion. Knee joint score and function score recovered to (92.0±4.7) points and (90.3±6.8) points at half years after replacement, and became (94.4±3.2) points and (91.6±5.9) points during final fol ow-up, which was significantly improved as compared with that pre-replacement (P<0.01). No revision surgery should be done for lining prolapse or spin out, osteolysis and prosthesis loosening. These results indicated that the early and midterm results of Gemini MKII rotating-platform prosthesis were satisfactory, but the long-term results remain to be confirmed.
9.Application of Ponseti method in patients older than 6 months with congenital talipes equinovarus
Yanzhou WANG ; Xiaowen WANG ; Peng ZHANG ; Xingshan WANG
Journal of Peking University(Health Sciences) 2003;0(04):-
0.01). Among the groups classified by deformity degree,the percentage of excellence was the lowest in severe group (P0.05). The number of casts used among different groups were different (P0.05). Conclusion:Using Ponseti method to treat CTE for children older than 6 months can achieve excellent results in this study.
10.Antitumor effect of chlorophyllin in vitro
Xiaowen DING ; Shu ZHENG ; Jiaping PENG ; Qinghua L ; Jian HUANG
Chinese Journal of Pathophysiology 1999;0(09):-
AIM: To study the effect and mechanism of chlorophyllin (CHL) inhibiting HT29 cells. METHODS: IC 50 value and growth curve of HT29 cells were detected with MTT method. Apoptosis was detected with Wright-Giemsa staining, FCM and DNA electrophoresis. Telomerase was detected by PCR-ELISA, and protein and mRNA expression of COX-2 gene were detected through RT-PCR and Western blot. RESULTS: CHL inhibited the growth of HT29 in a dose-dependent manner. CHL blocked HT29 cells in G 1 phase but did not induce apoptosis. Different concentration of CHL inhibits the expression of telomerase and COX-2 in HT29 cells. CONCLUSION: CHL inhibits the growth of HT29 cells by inhibiting the expression of telomerase and COX-2 and blocking cells in G 1 phase. [