1.MRI fingings of central neuroeytoma
Hongping LIN ; Xiaotong SHAO ; Haiquan YAO ; Tao ZHANG ; Peng ZHANG ; Xinqun QU
Journal of Practical Radiology 2017;33(6):536-538,550
Objective To analyze the MRI features of central neurocytoma (CNC),and to improve the diagnostic accuracy of this lesion.Methods The MRI findings of 12 patients with CNC confirmed by surgery and pathology were evaluated retrospectively.All patients underwent contrast-enhanced and uncontrast-enhanced MR scan,and 3 patients also received plain CT scan.Results The lesions of 12 cases were all located in the lateral ventricles of septum pellucidum,which were close to the Monro's foramen.5 lesions located in the right lateral ventricle,5 lesions located in both lateral ventricles with 1 case reached the third ventricle,2 lesions located in the left lateral ventricle with 1 case reached the third ventricle.The mean diameter of the CNC lesions was 4.8 cm (ranged from 2.2 to 7.8 cm).11cases (92%) had vavious degrees of cystic change,8 cases (66.7%) had a spongy or soap bubble appearance and 1 case(8.3%) had completely cystic change.3 cases (25%) had a scalloping appearance on sagittal T1-weighted MRI.The solid part of the tumor was similar to the gray matter in signal intensity,with slightly high signal intensity on T2FLAIR.Among 9 cases with DWI,7 cases showed high signal intensity,1 case showed equal signal intensity,and 1 case showed slightly low signal intensity.On enhanced MRI,the solid part of tumors showed slight to medium (83%) or obvious (17%) enhancement.Conclusion CNC should be first considered when a young adult has a lesion located in the lateral ventricles of septum pellucidum,accompainied by varying degrees of cysts,showed slight to medium enhancement in the solid part of the tumor.
2.Nutritional intake analysis of hospital diets in elderly inpatients in Peking Union Medical College Hospi-tal
Yanping LIU ; Shanshan LI ; Yuanyuan BAO ; Xiaotong YANG ; Wenjing WANG ; Rui LI ; Kang YU ; Yimin QU
Chinese Journal of Clinical Nutrition 2016;24(2):101-105
Objective To investigate the nutritional management level of Department of Clinical Nutrition in elderly inpatients through analyzing the actual hospital dietary intakes in elderly inpatients in Peking Union Medical College Hospital from 2013-2015.Methods Using continuous sampling, the nutrients contents and the eating rates of hospital meals ordered by the elderly inpatients on the 1st, 15th, 29th of every month from May 2013 to October 2015 were selected.The intake levels of energy, protein, calcium, vitamin A, vitamin B1 , and vitamin C were calculated and compared with the Chinese dietary reference intakes (DRIs).The nutritional in-take differences between diabetes diet and the basic hospital diet were also compared.Results A total of 90 days of hospital dietary data from 8 402 elderly inpatients were included in the study.The average eating rate was (50.1 ±4.2)%, which was lower than the general eating rate of the hospital [ (59.0 ±4.0)%, P<0.001]. Only protein intake from hospital diet reached the requirement target [male (103.1 ±47.3)%, femal (98.3 ± 33.8)%].Individual compliance rates were 63.2%and 59.8%, respectively, while the other kinds of nutrients were lower.The compliance rates of energy [ (73.3 ±26.3)%vs.(62.1 ±38.2)%, P<0.001] and ma-jor nutrient intake [ protein: ( 119.1 ±41.2 )% vs.( 93.3 ±65.1 )%, P <0.001; calcium: ( 55.5 ± 26.7)% vs.(34.3 ±34.2)%, P <0.001; vitamin A: (75.2 ±48.3)% vs.(57.4 ±97.1)%, P<0.001;vitamin B1:(76.4 ±38.2)%vs.(52.1 ±46.6)%, P<0.001;vitamin C:(92.2 ±51.4)%vs. (49.3 ±55.0)%, P<0.001) in diabetes diet group were significantly higher than those in the basic hospi-tal diet group.Conclusions The nutritional intakes from hospital diets may not meet the nutritional require-ments based on DRIs in elderly inpatients.Medical diet designed by physicians and dietitians should be ex-panded to improve the nutritional management level for these patients.
3.Self-management efficacy and quality of life in Parkinson disease
Man YUAN ; Anchun YIN ; Zhanhua LIANG ; Liyu YU ; Xiaotong QU ; Tingting ZHANG
Chinese Journal of Practical Nursing 2017;33(17):1297-1300
Objective To understand the quality of life and self-efficacy of Parkinson patients and explore the relationship between them. Methods A cross-sectional study was conducted on 155 Parkinson patients. The instruments included a self-designed general information questionnarie, the 39-item Parkinson's disease questionnaire (PDQ-39) and self-efficacy scale for chronic patients. Results The total score of the quality of life was 26.12 ± 16.31.The total score of self-efficacy was 5.46 ± 1.87, and the scores of symptom management and disease management were 5.23 ± 1.98 and 5.94 ± 1.96. The quality of life was positively correlated with self-efficacy (r=0.800, P < 0.01). Conclusions Parkinson patients' overall the quality of life and self-efficacy remain a low level, and the quality of life was closely correlated with self-efficacy. The score of patients' self-efficacy was higer, the quality of life was better. Medical and nursing personnel can through strengthening patients' self-efficacy, optimizating of the patient' s health behavior, and improving negative emotion and attitude, so as to improve their quality of life.
4.MRI features of primary lymphoma in central nervous system
Hongping LIN ; Dachun XIAO ; Xiaotong SHAO ; Haiquan YAO ; Xinqun QU
Journal of Practical Radiology 2018;34(3):347-350
Objective To study the MRI features of primary central nervous system lymphoma (PCNSL)to improve its diagnosis. Methods The MRI data of 1 3 patients with PCNSL confirmed by biopsy or surgical pathology were analyzed retrospectively.All patients underwent nonenhanced and contrast-enhanced MRI examinations.Results Multiple lesions in 8 cases and solitary one in 5 cases were found.Five leisons (38.5%)were located in the cerebral hemispheres.Eight(61.5%)were located in deep structures of the brain including periventricular white matter,basal ganglia,thalami and corpus callosum,6 (46.2%)of whom involved in the ependyma including 1 involved in the ependyma of the 4 th ventricle.One leison(7.7%)was located in the cerebellar hemisphere.The tumor showed isointense or mildly hypointense signal on T1WI,mildly hyperintense signal on T2WI and hyperintense signal on DWI.Mild to moderate perilesional edema was noted.The tumors in 13 cases showed remarkable homogeneous enhancement after the contrast agent was injected with the signs of characteristic notch,butterfly and satellite.Focal necrosis occurred in 1 lesions.Conclusion PCNSL shouldbe first considered when a lesion located in the deep central structeres of the brain,multiple and involve ependymal membrane,showed isointensity on T1WI and T2WI,highintensity on DWI in tumoral parenchyma demonstrated,significantly enhancement in the solid part of the tumor.
5.Design and manufacture of mind maps of outpatient pre-examination triage
Chunlu GE ; Xiaotong QU ; Xiaoling LU ; Li SUN
Chinese Journal of Practical Nursing 2020;36(16):1270-1274
Objective:To design and manufacture mind maps of outpatient pre-examination triage and provide references for the training of outpatient triage nurses.Methods:The mind maps team was set up, and the content of outpatient pre-examination triage was prepared preliminarily by searching literature and combining with clinical practice. The first draft of mind map of outpatient pre-examination triage was established by drawing software, and the final draft was determined after consultation and verification by experts.Results:The final mind maps of outpatient pre-examination triage are composed of three parts: head, neck and chest symptoms, abdominal symptoms and other symptoms. The mind maps of head, neck and chest symptoms and abdominal symptoms both include six modules, and the mind map of other symptoms includes five modules. Each module contains different disease symptoms and departments.Conclusions:This mind map is comprehensive and easily mastering. Meanwhile it can regulate outpatient pre-examination triage and give guidance of nurse training.
6.Investigation and analysis of outpatient nursing service needs based on kano model
Chunlu GE ; Hua ZHONG ; Xiaotong QU
Chinese Journal of Practical Nursing 2020;36(29):2303-2307
Objective:Application Kano model to analyze the nursing service demand of outpatients and promote the improvement of outpatient nursing service quality.Methods:Design a questionnaire for the outpatients’service requirements based on the model of Kano, including 4 parts, service and mental outlook, management and professional duties, health education guidance, outpatient management and convenience Services, composed of 28 items. Using Kano model analysis technology, we can determine the different attributes of outpatient nursing needs, including O expectation attribute, M essential attribute, A charm attribute, R opposite attribute, and Q question answer.Results:The nursing service needs of outpatients were classified by identifying the attributes of each demand. There are 8 items1, 10, 11, 15, 17, 18, 21, 22 attributed to the desired attribute (O). There are 11 items 2, 8, 9, 12, 13, 14, 23, 24, 26, 27, 28 attributed to the mandatory attribute (M). There are9 items 3, 4, 5, 6, 7, 16, 19, 20, 25, 28 attributed to the charm attribute (A) . At the same time, the quadrant diagram of satisfaction and importance of each item is constructed.Conclusion:Using the Kano model to analyze the nursing service demand of outpatients can determine the attributes of each demand, realize the priority of management project improvement, and provide decision-making reference for improving the quality of outpatient nursing service.
7.Research progress on regulatory network of competitive endogenous RNA in trophoblast biological behavior in preeclampsia
Doudou HE ; Xiaotong SUN ; Tao QU ; Xueping YANG ; Chunyang ZHANG
Chinese Journal of Perinatal Medicine 2022;25(9):709-713
Preeclampsia is a unique complication in the second and third trimesters of pregnancy, but its pathogenesis remains unclear and the early diagnosis and treatment methods are yet to be perfect. Termination of pregnancy at the right time is the only way to prevent its deterioration and avoid adverse pregnancy outcomes. In recent years, with the in-depth research, non-coding RNAs has been found to be involved in many important physiological and pathological processes such as proliferation and apoptosis of trophoblast cells and these non-coding RNAs can regulate each other to form an intricate and competitive endogenous RNA regulatory network. This article will introduce the biological roles of non-coding RNAs in regulating the invasion and proliferation of trophoblast cells in patients with preeclampsia and possible regulatory relationship between non-coding RNAs. Furthermore, the potential clinical value of non-coding RNAs as diagnostic biomarkers for preeclampsia and therapeutic targets are also elaborated.
8.Correlation analysis of mental resilience and quality of life in patients with Parkinson's disease
Tingting ZHANG ; Anchun YIN ; Guirong SONG ; Yingjun JIANG ; Xiaotong QU ; Zhanhua LIANG
Chinese Journal of Practical Nursing 2021;37(36):2826-2830
Objective:To investigate the relationship between mental resilience and quality of life in patients with Parkinson ′s disease and provide basis for paying attention to the mental health of this group. Methods:A total of 190 in patients with Parkinson ′s disease (PD) were selected from April to July 2017 in the First Affiliated Hospital of Dalian Medical University. The general data questionnaire, Mental Resilience Scale and 39-Item Quality of Life (QOL) Questionnaires were used to investigate among the patients. Results:The mental resilience score of PD patients was 48.0 (29.8, 62.2) points and the quality of life score was 56.0 (27.8, 82.0) points. There was a significant negative correlation between mental resilience and quality of life score ( r value was -0.538, P<0.01). Multivariate linear regression analysis showed that with the increase of psychological elasticity score, the score of quality of life decreased ( b value was -0.002, P<0.001). Conclusions:The mental resilience and quality of life of PD patients are both at a low level, the improvement of mental resilience is beneficial to improve their quality of life.
9.Three-dimensional radiographic features of calcifying odontogenic cyst and calcifying epithelial odontogenic tumor
Xiaotong LING ; Liuyang QU ; Danni ZHENG ; Jing YANG ; Xuebing YAN ; Denggao LIU ; Yan GAO
Journal of Peking University(Health Sciences) 2024;56(1):131-137
Objective:To analyze the three-dimensional radiographic characteristics of calcifying odon-togenic cyst and calcifying epithelial odontogenic tumor using spiral computed tomography(CT)and cone-beam computed tomography(CBCT).Methods:Clinical records,histopathological reports,and CBCT or non-enhanced spiral CT images of 19 consecutive patients with calcifying odontogenic cyst(COC)and 16 consecutive patients with calcifying epithelial odontogenic tumor(CEOT)were retrospec-tively acquired,and radiographic features,including location,size,expansion,internal structure and calcification,were analyzed.Results:Among the 19 COC cases(12 males and 7 females,with an average age of 27 years),89.5%(17/19)of the lesions originated from the anterior and premolar areas,100.0%of them exhibited cortex expansion,and 78.9%had discontinued cortex.Among the 16 CEOT cases(3 males and 13 females,with an average age of 36 years),81.3%(13/16)of the lesions were in the premolar and molar areas,56.3%of them exhibited cortex expansion,and 96.8%had discontinued cortex.According to the distribution of internal calcifications,these lesions were divided in-to:Ⅰ(non-calcification type):absence of calcification;Ⅱ(eccentric marginal type):multiple calcifi-cations scattered along one side of the lesion;Ⅲ(diffused type):numerous calcifications diffusely dis-tributed into the lesion;Ⅳ(plaque type):with a ≥ 5 mm calcified patch;V(peri-coronal type):multiple calcifications clustered around impacted teeth.Calcifications were present in 73.7%of COC le-sions,including 9 type Ⅱ,3 type Ⅲ and 2 type Ⅳ lesions,and 42.8%of CEOT lesions had calcifica-tion images,including 2 type Ⅲ and 5 type V lesions.Six COC lesions had odontoma-like images.Moreover,8 of 9 type Ⅰ CEOTs were histologically Langerhans cell-rich subtype,which had a smaller size(with an average mesiodistal diameter of 17.8 mm)and were not associated with impacted teeth.Conclusion:COC lesions tended to originate from the anterior part of the jaw and exhibit cortex expan-sion,and were sometimes associated with odontoma.CEOT commonly occurred in the posterior jaw and had discontinued cortex.Two lesions had significantly different calcification map.Over 70%of COC le-sions had calcification images,which were mostly scattered along one side of the cysts,far from the im-pacted teeth.Approximately 60%of CEOT lesions exhibited smaller size and non-calcification,and the remaining CEOT cases often had calcification images clustered around the impacted teeth.