Objective To develop an HPLC method for determination of paeoniflorin in Fufang Chishao Granula. Methods The separation was performed on a Waters C18 column (250 mm× 4.6 mm, 5μm) with acetonitrile-water (30∶70) as the mobile phase at the flow rate of 1.0 mL/min. The detection wavelength was set at 230 nm. Results Paeoniflorin showed good linearity (r=0.999 9) in the range of 0.266-5.32 μg, and the average recovery was 98.00%, RSD=2.22%. Conclusion The method is convenient, sensitive, accurate and repeatable. It can be applied to determination of paeoniflorin in Fufang Chishao Granula and control the quality of the preparation.

Objective To investigate the clinical application value of multi-directional liver acquisition with volume acceleration (LAVA)imaging in diagnosing adult intussusception.Methods Nine cases with adult intussusception confirmed by multi-directional LAVA imaging and operation were included in the study.The MRI manifestations were analyzed retrospectively.Results Of the 9 cases,there were 4 cases of small intestine intussusception,1 case of ileocecal intussusception,3 cases of ileocecum intussusception and 1 case of colon intussusception.MRI features showed"target"sign in 9 cases,"bowel within bowel"sign in 4 cases,"kidney-shaped"mass in 8 cases,double"target"sign in 3 cases,"8"character sign in 3 cases,mesenteric lymph node tumescence in 1 case and ileus in 1 case.Conclusion The multi-directional LAVA imaging can help to show the various features of intussusceptions.