1.Risk analysis of malignant tumor among medical diagnostic X-ray workers during 1997-2011 in Jiangsu province
Yufei LIU ; Furu WANG ; Ningle YU ; Xiaosan XU ; Xiaoqing CHENG ; Yinghua FU ; Quanfu SUN
Chinese Journal of Radiological Medicine and Protection 2015;35(6):455-460
Objective To continue following up the cohort members in Jiangsu province who were the largest subgroup in Chinese medical X-ray workers cohort subgroups on radiation carcinogenesis and analysis the cancer risk of medical X-ray workers which might be induced by chronic low-dose ionizing radiation between 1997 and 2011.Methods A retrospective cohort study was utilized to accumulate data.Epicure was applied to compute cumulative person years (with module of Datab) and relative risk (including 95% CI) of malignant tumor on exposed group(with module of AMFIT) while the factors such as sex and attained-age were adjusted in the cohort members.Results The 7 708 follow-up members included 3 668 medical X-ray workers.The cumulative person-year in the cohort members was 94 651.2 (1997-2011) and its lost rate was 5.79%.During the follow-up period,441 cases had became cancer patients.The relative risk of all cancers was 1.44 (95% CI:1.18-1.75),so was the solid cancers.Significant elevated risks of cancer were found on lung (RR =1.95,95% CI:1.30-2.92),esophagus (RR =3.04,95% CI:1.20-7.70),lymphoma(RR =2.24,95% CI:0.67-7.48),leukemia(RR =1.57,95 % CI:0.33-7.39),throat (RR =2.47) and thyroid (RR =2.80,95 % CI:0.24-32.26) among medical X-ray workers.However,The RR of malignant tumors might not be associated with occupational exposure to ionizing radiation if we considered the lost factors (RR =1.2,95% CI:0.94-1.46)Conclusions The RR of malignant tumors such as the cancer on lung,esophagus,thyroid among the medical X-ray workers in Jiangsu province were enhanced which might be associated with occupational exposure to ionizing radiation.
2.Effect of pernasal high-flow nasal catheter wet oxygen therapy on treating middle-aged and elderly patients with severe refractory pneumonia complicated with respiratory failure
Journal of Clinical Medicine in Practice 2018;22(1):10-13
Objective To study the effect of pernasal high-flow nasal catheter wet oxygen therapy for middle-aged and elderly patients with severe refractory pneumonia complicated with respiratory failure and its effect on quality of life.Methods A total of 100 elderly patients with severe refractory pneumonia complicated with respiratory failure were enrolled in our hospital,and were divided into control group and study group according to the random number table method,with 50 cases in each group.The patients in the control group received pernasal continuous positive pressure ventilation therapy,and the patients in the study group received nasal high-flow nasal catheter wet oxygen therapy.The disappearance time of clinical symptoms,hospitalization time,treatment effect and survival quality were compared between the two groups after treatment.Results The study group had lower disappearance time in cyanosis,lung rales,shortness of breath,three incarads and hospital stay than the control group (P < 0.05).The total effective rate was higher than that of the control group (92.0% vs.74.0%,P < 0.05).After the treatment,the social,environmental,psychological and physiological scores of the study group were higher than that of the control group,and the differences were statistically significant (P < 0.05).Conclusion Pernasal high-flow nasal catheter wet oxygen therapy in the treatment of severe refractory pneumonia patients with respiratory failure has significant efficacy,and it can effectively relieve clinical symptoms and signs,and improve patients'quality of survival.
3.Effect of pernasal high-flow nasal catheter wet oxygen therapy on treating middle-aged and elderly patients with severe refractory pneumonia complicated with respiratory failure
Journal of Clinical Medicine in Practice 2018;22(1):10-13
Objective To study the effect of pernasal high-flow nasal catheter wet oxygen therapy for middle-aged and elderly patients with severe refractory pneumonia complicated with respiratory failure and its effect on quality of life.Methods A total of 100 elderly patients with severe refractory pneumonia complicated with respiratory failure were enrolled in our hospital,and were divided into control group and study group according to the random number table method,with 50 cases in each group.The patients in the control group received pernasal continuous positive pressure ventilation therapy,and the patients in the study group received nasal high-flow nasal catheter wet oxygen therapy.The disappearance time of clinical symptoms,hospitalization time,treatment effect and survival quality were compared between the two groups after treatment.Results The study group had lower disappearance time in cyanosis,lung rales,shortness of breath,three incarads and hospital stay than the control group (P < 0.05).The total effective rate was higher than that of the control group (92.0% vs.74.0%,P < 0.05).After the treatment,the social,environmental,psychological and physiological scores of the study group were higher than that of the control group,and the differences were statistically significant (P < 0.05).Conclusion Pernasal high-flow nasal catheter wet oxygen therapy in the treatment of severe refractory pneumonia patients with respiratory failure has significant efficacy,and it can effectively relieve clinical symptoms and signs,and improve patients'quality of survival.