OBJECTIVE:To evaluate the inhibitory effect of hydrocortisone on fentanyl-induced cough reflex(FIC).METHODS:160 patients undergoing scheduled operation on abdominal region were randomized to receive Normal Saline 100 mL(Group Ⅰ)or hydrocortisone 100 mg added to 100 mL Normal Saline iv gtt(Group Ⅱ);15 minutes later,both groups were injected intravenously with fentanyl(2 ?g?kg-1)with injection time of 2 seconds.The frequency and the onset time of cough as well as the adverse drug reactions in the two groups were observed.RESULTS:The FIC incidence in Group Ⅱ was significantly lower than in Group Ⅰ(10% vs.35%),showing significant differences between the two groups(P

Objective:To investigate infection status of hepatitis B virus in ChongQing children. Method:We detected the HBV serology markers(HBVM) hy ELISA in 8060 children in Children's Hospital of Chnngqing Medical University. Results:HBsAg positive rate was 4.44%,anti—HBs positive rate 46.56%. 3795 cases were negative in HBVM(47.08%);259 cases were positive in HBsAg,HBeAg and anti-HBc(3.21%);80 cases were positive in HBsAg, anti-HBe, anti-HBc (0.99%),and Pre-S1 positive rate was 3.51%. Conclusion:Among the 8060 children who came to our hospital,the infection rate of HBV is 4.44%,lower than in the adults. Pre-S1 is related with HBeAg,and it can reflect the status of HBV multiplication and infectivity to some extent.

Objective:establishment a Laboratory Information Management System.Methods:The interface is designed by visual basic 6;the database managed by ACCESS;the enquiry and statistic work is finished by SQL sentences;data is received by utilizing Active X control;and the report work is finished by Printer object and DataReport designer.Results:This system has over-all functions,beautiful interface and resistant database,it performs the common statistics and supervisory functions basically.Conclusion:There are some innovative things such as three-steps management pattern,dynamic contrast current record with historical information,variegated seek and statistics,humanization design and utility tools.on the whole,it is a software which can service the needs of clinical work and has a broad future.

Objective To evaluate the prevention and treatment of prosthetic infections after tension free hernioplasty. Methods The clinical date of 12 prosthetic infections admitted from May 2005 to May 2008 were analyzed retrospectively. Patch was inserted under prefascial retromuscular site in 8 cases, between fascial edges in 2, Mesh plug and patch Lichentstein in one each. As for the material used there were flat knitted polypropylene in 7 cases, polytef in 1 case and composite prosthesis in 4 cases. Treatments were based on prothetic materials and levels infected. Infectious patchs were removed completely in 8 cases and partially removed in 2 cases, Open dress change with patchs left in situ in 2 cases. 3 cases in 10 cases of removed patchs were given immediate suturation with closed drainage. Results Infection was cured in all cases without mortality. There was no hemorrhage and injury of bladder during the procedures. No retention of urine, pain and other complications during postoperation. Change of dressing was made from 7 days to 6 months( median 2 weeks). Selected antibiotic was used from 3 to 7 days (average 4.5 days). All patients were followed up from 18 to 78 months (average 38.5 months) without hernia recurrence and infection. Conclusion It was most important to prevent infections after tension-free hernioplasty. Management should be individualized according to different type of patch used and the surgical procedure in hernia repair.

Objective To analyze the clinical characteristics of adult intussusception and improve its diagnostic and treatment levels.Methods Data of 80 cases of adult intussusception treated in the First Affiliated Hospital of China Mdeical Unuversity between January 2001 and December 2015 were reviewed retrospectively.Results 95％ patients had abdominal pain,34％ had bloody stool and 24％ had abdominal mass,8％ presented a triad of abdominal pain,bloody stool and abdominal mass.As confirmed by laparotomy 48％ were enteric intussusception,40％ were ileocolic intussusception,and 12％ colocolonic intussusception.The diagnosis rate of abdominal uhrasonography was 60％;CT established the diagnosis in 97％ cases.74％ underwent malignant or benign tumor resection,10％ underwent intestinal resection for inflammatory bowel disease.10％ were cured by simple reduction.4 cases received intussusception reduction and appendectomy.Conclusions Tumors were causes of adult intussusception in most case.CT is most accurate in diagnosis.Laparoscopy can be used for difficult diagnosis.

Objective To investigate the functional changes of endothelial cells (EC) in non-thrombosis vein segment (ECNT) in rats with experimental venous thrombosis (VT). MethodRats were divided into normal, control, and thrombosis group caused by legating a portion of iliac vein with 30 animals in each group. Endothelium was sampled from superhepatic IVC. Samples were studied by electroscopy, immunohistochemistry, and Western blotting for apoptosis. ResultsMorphological and functional changes of the ECs were observed in sampled superhepatic IVC. Compared with normal and control group the apoptosis rates(P

Objectives To evaluate methods to diagnose Budd-Chiari syndrome with inferior vena cava (IVC) thrombosis.Methods 31 cases underwent phlebography, 28 cases received color Doppler sonography preoperatively. Radical thrombectomy was carried out in 28 cases. Results IVC thrombi was found by phlebography in 24 cases, and by color Doppler sonograhy in 25 cases. There was no intraoperative death, nor acute pulmonary embolism.All patients were discharged uneventfully. Follow-up of 6 to 80 months found recurrence in 3 cases.Conclusions Large or lateral thrombi can be easily diagnosed by phlebography. Fresh or floating thrombi often missed by phlebography could be rushed out by blood stream at the time IVC was incised.The thrombi adhered to the IVC wall could be taken out with large balloon catheter or manually.

In order to explore the clinical feature, diagnosis and differential diagnosis of adrenal incidentalomas, we reviewed 98 cases of adrenal incidentalomas for which adrenalectomy was performed in our hospital from 1993 to 2002. It was found that the average age of the patients was 48 years old, 16 cases (16 3%) had no specific symptoms, and others were incidentally diagnosed. Of the 98 cases, 18 (18 4%) were malignant lesions, including 8 metastatic cancers, 8 adrenal carcinomas and 4 lymphangioma, and 80 were benign lesions. Twenty one cases were functioning adrenal adenoma. Ultrasound, CT scan, MRI or MIBG were effective methods to detect adrenal incidentalomas.

In order to investigate the distribution and diagnosis of adrenal tumors, 282 cases of patients who had undergone adrenalectomy in our hospital from March 1993 to December 2001 were reviewed. There were 147 (52 1%) women and 135 (47 9%) men, with a mean age of 43 6?13 0 (3～75) years. Of the 282 patients, 83 patients (29 4%) were operated on because of hyperaldosteronism, 59 (20 9%) pheochromocytoma, 27 (9 5%) hypercortisolism, 105 (37 2%) incidentaloma, 36 (12 8%) malignant tumors and 13 (4 6%) for other reasons. The average diameter of adrenal tumors was 4 8?3 4 (0 3～22 5)cm. The size of tumor mass was smallestin hyperaldosteronism, while the largest was malignant tumor. The conformation rate of the preoperative diagnosis and pathological findings was 65 2%.

Objective　To evaluate the results of radical resection for the treatment of Budd-Chiari syndrome (BCS) caused by short segmental lesions in inferior vena cava (IVC), and major hepatic veins (MHV).　Methods　In this series, resection of IVC occlusive segment and orthotopic artificial vascular graft transplantation were performed in 42 patients. Resection of major hepatic vein, hepatic venous plasty and orthotopic transplantation with artificial vascular graft were performed in 10 patients. Resection of major hepatic vein, anastomosis between hepatic vein and right artrium in 3 cases. Percutaneous transhepatic angioplasty in 10 cases.　Results　One patient died of complication. 58 cases were followed up for an average of 30 months. 3 cases in interventional group suffered recurrence and one in surgical group had recurrence.　Conclusions　The treatment of BCS by resecting inflicted segment of IVC or hepatic veins and orthotopic artificial vascular graft transplantation effect a radical cure in most cases.