China ; Surgery/*history

s international forum of higher education focused on the theme of characteristics,personality and a powerful country with talents and the common understanding was reached.That is only by orientating scientifically,running characteristically and cultivating more and more talents of high quality,personality and creativity,can Chinese higher institutions of learning shoulder the historical task entrusted by the strategy of propelling China to be a power country of opulent human resource.

Carrying forward the reform of quality education in universities,we should pay more attention to the integration of specialized education and general education,emphasize the training of creative competence,and never neglect the cultivation of the humane quality,which is the original purpose of quality education.

The preventive theory of traditional Chinese medicine means treating before occurrence or transference of diseases, which guides the modern health work. This paper analyses some health problem of citizens, proposes the solution and suggestion. Treating before occurrence or transference of diseases should not only be a medical ideal and the true approach is to strengthen system health education to citizens, especially all the students in school.

Objective To investigate and analyze the problems of nursing undergraduate during clinical practice period,and to give improving measures and provide experiences for im-proving clinical teaching quality.Methods The study was carried out through anonymous inves-tigative questionnaire that included student group(n=98) and teacher group(n=22).Results The majority were satisfied with practice arrangement and teaching attitude.Forty four percent students thought that teaching methods should be improved.The major problems from the teacher's questionnaire were that students'basic knowledge needed to be strengthened and there were dif-ferent problems exsisting in studnets in different practice stage.Conclusions To give some im-proving suggestions with analyzing the questionnaires.

Objective To summarize and analyze the examination result of serum specific IgE in patient with allergic skin disease,and seek the cause of disease for the allergic skin disease patient and provide the clinical treatment basis.Methods The serum specific IgE of ingestion and inhalation were detected by enzyme-linked immunoassay in 529 patient with allergic skin disease.Results In 529 cases,the serum specific IgE of inhalation and ingestion were positive in 336 cases,and simple positive of inhalation were in 92 cases,and simple positive of ingestion were in 51 cases.In the inhalation group,D1,1D2 (dust mites,mites) was highest,followed by T3,T8,T11,T18,T70 (birch,elm,eucalyptus,and indus,and the mulberry tree) and H1 (house dust).In the ingestion group,F13,F17 (peanut,hazelnut) was highest,followed by F3,F40,F37 (COD,tuna,scallop),F47,F48,F263 (garlic,onion,green pepper).In 14 items,more than one item were positive in 96.2％.Concluslon Detecting allergic skin disease patients serum allergen specific IgE can guide patient awareness of their allergen and clinical treatment,which has effect on allergic skin disease prevention and treatment.

Objective To understand the distribution characteristics of HIV infection status among the outpatients in this hospi-tal to provide the beneficial supplement for local large-scale survey and the basis especially for the hospital infection control.Meth-ods The HIV screening situation on the outpatients of our hospital from 2007 to 2012 was retrospectively analyzed.Results Dur-ing these 6 years,108 999 specimens were detected,88 cases were positive in the preliminary screening and 81 cases were confirmed positive.The positive rate of anti-HIV antibody was 0.074%.In addition to voluntary counseling and testing,the specimens submit-ted by the outpatient anorectal department and the inpatient hematology department had the higher positive detection rate,which was 1.16% and 0.84% respectively.Conclusion The HIV infection rate in non-infectious disease specialized hospitals shows the increasing trend.The key departments must increase the intensity of the medical staff training,pay attention to early diagnosis of HIV/AIDS,prevent the hospital infection and reduce the risk occurred after the occupation exposure.

Caudate lobectomy is still a great challenge for surgeons due to unique anatomy of caudate lobe.A 38-year-old male patient with a huge recurrent hepatic cancer (diameter =16 cm) in caudate lobe received caudate lobectomy with portal triad and inferior vena cava clamping.The operation was paused due to hemorrhage (volume of blood loss =1000 ml).After heat preservation and blood transfusion,the caudate lobectomy was completely removed with inferior vena cava clamping.The patient gradually recovered,and no tumor recurrence was detected during the follow up (14 months).Caudate lobectomy could be safely carried out under the condition of accurate preoperational estimation,clear indication for surgery and precise hepatectomy.

Objective To investigate the role and expression of serum substance P (SP) in the patients with breast cancer.Methods The quantity of serum SP by using ELISA in 21 patients with breast cancer (breast cancer group) and 10 healthy women (control group) were detected,the data were analyzed according to AJCC guide line.Results The positive rate of serum SP in breast cancer group was significantly higher than that in control group [57.1％ (12/21) vs.0] (P ＜ 0.01).The level of serum SP in breast cancer group was significantly higher than that in control group [(240.14 ± 435.04) ng/L vs.(16.80 ± 11.74) ng/L](t =2.9852,P ＜ 0.01).There was no relationship between serum SP and estrogen receptor in the patients with breast cancer (t =0.1856,P ＞ 0.05).The level of serum SP showed significantly difference according to AJCC stages respectively (F =3.24,P ＜ 0.05).Conclusion The level of serum SP in the patients with breast cancer increase and may play a role in the progress of breast cancer.

Objective To investigate the protective effects of Lycopene (LP) on hepatic oxidative stress injury in type 2 diabetic rats.Methods The diabetic rat models were setup by intraperitoneal injecting STZ (60 mg/kg). 60 models were selected and randomly divided into three groups: diabetes model control group, LP 10 and 20 mg/kg treated groups, with 20 experimental animals in each group. While, selected another 20 normal same-aged rats as normal control group. The drug was given by intragastric administration for 4 weeks, once a day. Before the drug was given and after 2, 4 weeks, the level of blood sugar was determined. Four weeks later, the body weight and hepatic index were detected; the activity of ALT, AST, ALP and the level of T-AOC in serum were determined; the activity of SOD, GSH-Px, CAT and the content of MDA in hepatic tissue were determined; and the hepatic tissue histopathological changes was observed by HE staining.Results Compared with the diabetes model group, the activity of ALT in serum of LP 10, 20 mg/kg treated groups was significantly decreased (714.8±291.5 U/L, 862.7±348.1 U/Lvs. 1 007.6±375.7 U/L); AST was significantly decreased (75.2±18.6 U/L, 87.6±20.3 U/L vs. 99.3±21.5 U/L); and the content of MDA in hepatic tissue was significantly decreased (5.56±1.02 U/L, 5.83±0.98 U/L vs. 6.37±1.18 U/L); the blood sugar level of LP  20 mg/kg treated group was significantly decreased(16.6±1.1 mmol/L vs. 17.9±1.2 mmol/L), the body weight was significantly increased(281.5±24.8 g vs. 252.3±23.5g) and the hepatic index was significantly decreased (26.2±5.3 ‰vs. 30.4±5.8‰), the activity of ALP in serum was significantly decreased (135.2±30.8 U/L vs. 167.4±32.5 U/L) and the level of T-AOC was significantly increased (10.8±2.8 U/L vs. 8.7±2.4 U/L), the activity of SOD in hepatic tissue was significantly increased(10.8±2.3 U/mgvs. 9.1±2.3 U/mg), GSH-Px was significantly increased (16.1±3.4 U/mgvs. 14.3±3.5 U/mg), CAT was significantly increased (3.16± 1.08 U/mgvs. 2.63±0.90 U/mg).ConclusionLP had dose-dependent protective effect for hepatic oxidative stress injury in type 2 diabetic rats.