Introducing the current challenges of library of Institute of Information Research, China Rehabilitation Research Center,the paper puts forward the establishment of effective literature resources construction and reader service mechanism. Construction of library collection should be developed from two aspects, namely, the acquisition and integration parts, so as to develop characteristic,compound collections with both printed literatures and digital literatures. Reader service is not only including the traditional service but also covering deep-rooted professional information analysis and multiple types of services.

It is no doubt that obstetrics and gynecology contains profound philosophic thinking.To integrate the philosophical thinking of materialistic dialectics and dialectical unity in obstetrics and gynecology teaching is helpful to reveal the essence from obstetrics and gynecology phenomena.Application and cultivation of philosophical thinking may be useful to further explore students'comprehensive thinking potential and effectively improve the quality of obstetrics and gynecology teaching.

Urotensin Ⅱ,a cycle peptide originally found from the fish,is the most potent vasoconstrictor.Urotensin Ⅱand its receptor have been found in central nerve system,cardiovascular system and other organs and tissues.It has been suggested that urotensin Ⅱplays important roles in the physiological and pathological procedures.Based on the evidences obtained from experiments,urotensin Ⅱmay become a new target for treating many diseases,particularly for cardiovascular diseases.

Objective To study the cause of different prognosis in typical medullary carcinoma and atypical medullary carcinoma. Methods The immunohistochemical staining method was used to evaluate the positivity of E cadherin,? catenin, in 30 cases of atypical medullary carcinoma and 18 cases of typical medullary carcinoma and 10 cases of normal breast. Results The positive rate and staining intensity of E cadherin and ? catenin oncoprotein were significantly higher in typical medullary carcinoma than in atypical medullary carcinoma( P

Objective: To evaluate the effect of propofol on coronary circulation of acute myocardial ischemia-reperfusion inury. Metbod: 18 hybrid dogs (11-14kg) were divided randomly into three groups:NS group (normal saline, 2ml?kg~(-1)?h~(-1)), HP group (high-dose propofol, 11.2mg?kg~(-1)?h~(-1)), LP group (low-dose propofol, 5.6mg?kg~(-1) ?b~(-1)). These dogs were subjected to 90 min left anterior descending coronary artery (LAD) occlusions followed by 200 min of reperfusions. Before administration, 60 min after administration, 60min, 120min, 180min following reperfusion,coronary circulation was assessed by measurement of coronary perfusion pressure (CPP) and blood flow of LAD. Result: The values of CPP in HP and LP groups 60 minafter administration were significantly lower than those in NS group before LAD occlusion (P

objective:To evaluate the effeets of Propofol on left ventrieular funetion of aeute myoeardial isehemia-reperfusion injury in eane.Method:Eighteen hybrid dogs(11一14kg)were divided randomly inro three groups:NSgroup(norrnal saline,Zml?kg一l?h一1),HP group(high一dose propofol,11.Zmg?kg一1?h一1),LP group(low一dosepropofol,5.6mg?kg一'?h一').These dogs were subjeeted to a 90一min left anterior deseending eoronary artery oeelu-5 ion followed by 200min of rePerfusion.Before ad而nistrat一on,60min after administration,at oeelusion一90min and60min.12Ornin and180min壬ollowing reperfusion left ventrieular funetion was assessed by measurement of LVSP,LVEDP,dp/dtmax and dP/dtmin.Result:Compared with the baselines,LVSP,dp/dtmax and dP/dtmin 60 min afteradrninistration deereased byg%,17%and 17%respeetively,LVEDP inereased by 80%in HP grouP.120min and180min during reperfusion LVSP.dp/dtmaxanddp/dtmininHPandLPgroupweresignifiea八tlyhigherthanthoseinNs group。.05),LvEDP signifieantly lower than that in NS group(p

OBJECTIVE To investigate the related factors of hospital-acquired infection in our hospital for prevention and control of infection.METHODS We carried out a prospective and retrospective study of 26 424 hospitalized patients in our hospital from Jan to Dec 2006.RESULTS From then 1261 patients had hospital-acquired infection(4.77%),the total infection case-time was 1380(5.22%).CONCLUSIONS Hospital-acquired infection is closely related to patients,underlying diseases,old age,invasive procedure,hospital stay and inappropriate antimicrobial agents use.It requires us to strengthen the surveillance of hospital-acquired infection,decrease the unnecessary invasive procedures,shorten hospital stay and use antimicrobial agents appropriately.

[Objective] To investigate the protective effects of different extraction of Agaricus blazei Murrill on HaCaT cells damaged by UVB. [Methods] The cell viability which was detected by MTT method was used to determine the impact of different dose of UVB and different extraction of Agaricus blazei Murrill on normal HaCaT cells and HaCaT cells damaged by UVB. [Results] ①The HaCaT cells viability declined after irradiation with UVB, and it was a dose-dependent manner. The cell viability was 53.23%when the dose of UVB was 20mj/cm2. ②The water extraction at the concentration of 0.2~4mg·mL-1, aqueous extraction at the concentration of 0.1~2mg·mL-1 and crude polysaccharide at the concentration of 0.2~1mg·mL-1 could promote the proliferation of HaCaT cells, while aqueous extraction and crude polysaccharide inhibited the proliferation of HaCaT cells at higher concentrations.③The water extraction at the concentration of 1~4mg·mL-1, aqueous extraction at the concentration of 1~2mg·mL-1 and crude polysaccharide at the concentration of 0.5~1mg·mL-1 could enhance the cells viability which was irradiated by 20mj/cm2 UVB (P<0.01). [Conclusion] The different extraction of Agaricus blazei Murrill all could relieve the photo-damage caused by UVB, and it has the potential of anti-photoaging.

Objective To study the effects of P53, PCNA, Bcl-2 protein and their relationship in salivary adenoid cystic carcinoma(SACC). Methods These proteins were examined by immunohistochemistry. Results Overexpressions of P53 and PCNA were revealed in ACC samples, they were higher than those in (polymorphous adenomas) PA, but expression of Bcl-2 protein was not different between ACC and PA. In 3 subtypes of ACC, expressions of 3 proteins were different. Conclusion Mutations of P53, Bcl-2 may be involed in the occurrence of SACC, expression of PCNA and mutation of P53 may coexist in the development of the SACC.

Objective:To investigate the impact of conditioned medium of decidual stromal cell culture(DSCM) on proliferation,apoptosis and invasion of trophoblast cells.Methods:lsolution,culturing and indentifying the purity of decidual stromal cells from healthy women of early pregnancy to prepare different concentrations of DSCM (5％,20％,50％ and 100％);Proliferation was evaluated by MTT assay;Cell apoptosis was examined by flow cytometry using annexin V-FITC/PI staining;Cell invasion was assayed using a Transwell chamber;RT-PCR and gelatin zymography were used to explore the mechanism of cell invasion.Results:Using this method we obtained a purity over 90％ of decidual stromal cells.With the concentration of DSCM increased(5％,20％,50％,100％),the OD value of the MTT assay has elevated and the rate of apoptosis declined,the infiltrating cell increased as well (P ＜ 0.05);Compared with control group,DSCM treatment led to a significant increase in the mRNA and protein expression of MMP-2/9(P ＜0.05).Conclusions:Decidual microenviroment may promote trophoblast proliferation and inhibite its apoptosis besides could enhance its ability of invasion by altering the expression of MMP-2 and MMP-9.