1.The effects of two-suppression therapy compared for school-age children with monocular amblyopia
Chinese Journal of Postgraduates of Medicine 2009;32(12):10-12
Objective To compare the effectiveness of two-suppression therapy with over-plus hyperopia lens and atropine mydriasis for school-age chihtren with monocular amblyopia. Method One hundred and sixty-seven cases of children with monocular amblyopia in the age of 7-12 years old were observed, who were randomly divided into two groups, using over-plus hyperopia lens or atropine mydriasis to suppress the normal eye, and the amblyopia eye was comprehensive trained, followed-up of 3 years. Results The effect rate was similar between over-plus hyperopia lens and atropine mydriasis [90.7%(78/86) and 91.4%(74/81), respectively]. There was no significant difference (P>0.05). Conclusions For school-age children with monocular amblyopia, you can use over-plus hyperopia lens inhibit the normal eye sight, its effect is similar with the atropine mydriasis.
2.Predictive value of cord blood bilirubin level for subsequent neonatal hyperbilirubinemia in ABO hemolytic term infants
Chinese Journal of Perinatal Medicine 2015;18(1):20-23
Objective To evaluate the predictive value of cord blood bilirubin levels for subsequent neonatal hyperbilirubinemia in term infants with ABO hemolytic disease.Methods A total of 292 term newborns with ABO hemolytic disease admitted from August 1,2011 to July 31,2012 were enrolled.Cord blood bilirubin levels were analyzed and the clinical characteristics of the neonatal hyperbilirubinemia group (n=34) and non-hyperbilirubinemia group (n=258) were compared.A receiver operating characteristic (ROC) curve analysis was performed to identify the predictive value of the occurrence and cut-off point of hyperbilirubinemia in term infants with ABO hemolytic disease.Paired-t-test,Chi-square test and Spearman correlation were used for statistical analysis.Results Of the 292 term infants with ABO hemolytic disease,34 cases had hyperbilirubinemia,with an incidence of 11.6%.Cord blood bilirubin levels were significantly associated with the presence of hyperbilirubinemia.The mean cord blood bilirubin level in infants who developed hyperbilirubinemia was (52.4± 13.2) μ mol/L,and was (35.0±8.0) μ mol/L for those who did not develop hyperbilirubinemia (t=7.540,P=-0.001).When cord blood bilirubin concentration increased,the incidence of hyperbilirubinemia gradually increased (x2=113.715,P<0.001; rs=7.19,P<0.001).The ROC area under the curve of 0.882 (standard error 0.005,95%CI:0.873-0.891,P<0.001) was significant in predicting neonatal hyperbilirubinemia by cord blood bilirubin,and the occurrence of hyperbilirubinemia increased with increasing cord blood bilirubin level.Neonatal cord blood total bilirubin ≥ 50 μ mol/L predicted hyperbilirubinemia,and the positive predictive value was 0.683,negative predictive value was 0.959,sensitivity was 0.690 and specificity was 0.958.Conclusions Cord blood bilirubin level is useful in predicting subsequent neonatal hyperbilirubinemia in term infants with ABO hemolytic disease.
3.Way of DIB Derived from DICOM Medical Image File
Chinese Journal of Medical Physics 2009;26(6):1500-1503,1512
Objective: According to clinical investigation, analysis on the storage format of DICOM3.0 medical images files and displaying them is the basis of medical image processing. It is very important for medical imaging technology. Methods: Firstly, with the DICOM standard, the format of the medical images is studied, mostly the format of the information header and data element. Then the DIB display of the DICOM images in Windows platform is put forward, using linear window-transformation. Results: It is successfully realized the display of CT、MR images. With the manual window-transformation, the displaying would be better. Conclusion: As the results show, the method studied in the paper can preferably realize the display of the DICOM medical images, meeting certain clinical needs, and laying a foundation for the following study.
4.Prevention of the superior laryngeal nerve injury at endoscopic thyroidectomy through subclavicular approach
Yingbin LI ; Faya LIANG ; Xiaoming HUANG
Chinese Journal of Postgraduates of Medicine 2014;37(8):27-30
Objective To discuss the methods of the prevention of the superior laryngeal nerveinjury at endoscopic thyroidectomy through subclaviclar approach.Methods The clinical data of 100 patients with thyroid diseases received endoscopic thyroidectomy through subclavicular approach were analyzed retrospectively.Nodular goiter in 69 cases,adenoma in 18 cases,simple goiter in 13 cases.Line side lobe resection in 35 cases,the side lobe subtotal in 8 cases,the side lobe resection + subtotal contralateral lobe in 48 cases,bilateral subtotal gland in 9 cases.Results All 100 patients after surgery pronounced normal,no tone deep,choking water,etc,patients 7-30 d laryngoscope review found no abnormalities.Conclusion Thyroidectomy through subclavicular approach under endoscope is calleidic thyroidectomy,effectively avoid permanent superior laryngeal nerve injury.
5.Comparative study of MRI and pathological findings in senile endometrial polyp
Xiaoming WANG ; Xianlong HUANG ; Biqiang LI
Journal of Practical Radiology 2014;(8):1341-1343,1354
Objective To analyze the MRI features of senile endometrial polyp and compared MRI features with pathological find-ings,to improve the ability for the diagnosis.Methods The study included 58 cases with senile endometrial polyp proved by diag-nostic curettage or hysterectomy.MRI and pathological findings were analyzed retrospectively.Results Among 58 cases,there were 46 cases with and 12 cases without uterine cavity enlargement.Lesion combined solid portions with cryptomere cystics areas filled in uterine cavity in 35 cases,and MRI showed hypointensity on T1 WI,mixed intensity with hypointensity separation lines on T2 WI, and marked heterogeneous enhancement.The signal of uterine cavity was heterogeneous in 23 cases with hypointensity or isointensi-ty on T1 WI,hyperintensity or isointensity on T2 WI,and no obviously enhancement.Conclusion MRI combined with clinical fea-tures can improve the diagnostic accuracy of senile endometrial polyp.
6.Study on the Antidepressant Effects and Mechanism of Hypericum Perforatum L.(EHP)in Stress-induced Depressive Model
Xiaoming ZHONG ; Qingqiu MAO ; Zhen HUANG
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To study the antidepressant effects and mechanism of Hypericum peratum L.(Elqe).[Methods]Forced-swimming test in mice,tail-suspension test in mice mensurating cerebracontents of monoamine neurotransmitters in chronic stress-induced depressive rats done to study the antidepressant effects and mechanism of extract of Hypericum peratum L [Results]Immobility time of forced-swimming and tail-suspension in mice which were significantly shortened by EHP (320mg/kg,160mg/kg)(P
7.FUSION OF HEPATOMA CELL
Xiaoming OU ; Junming WANG ; Chen HUANG
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(01):-
Both molecular weight 6000 and 1000 polyethylene glycol (PEG) have been used to induce thc fusion of hepatoma cell by two methods of centrifugation and stillstand. The results showed that 50% PEG of molecular weight 1000 and centrifugation increase the percentage of fused cells. The procedure of cell fusion has been examined. The cytoplasm has been fused when the cells start fusing in one hour and a half, and the neucleus start fusing in two horus and a half.
8.The Least Squares Polynomial Fitting Design Denoise Based on the Volume Pulse Wave Detection System
Beibei QI ; Xiaoming WU ; Yueshan HUANG
Chinese Journal of Medical Physics 2009;26(6):1521-1523
Purpose: Use of BCI clip-on probe for blood volume transmission pulse wave detection, through the signal conditioning amplifier circuit, A/D conversion circuit, microcontroller and interfaces to collected data to the PC. The applications of software filtering to improve hardware filtering. Methods: This article is carried out in MATLAB based on the least squares polynomial fitting of the low-pass FIR filter denoising simulation. Results: Removal of well-frequency and other interference, access to clean pulse volume waveform. Conclusion: To facilitate real-time display in the interface and for the latter part of the feature extraction and parameter calculation
9.The Application of Fat-suppressed Spoiled Gradient-Echo (3D-FS-SPGR) Sequence in Association withThree-Dimensional Reconstruction in Cartilage Disorder of Knee
Sirun LIU ; Xiaoming LENG ; Li HUANG
Journal of Practical Radiology 1992;0(11):-
Objective To evaluate the clinical value of 3D-FS-SPGR and 3D-reconstructional technique in detecting the lesion of articular cartilage of knee.Methods Fifty eight knees with OA(42 cases)or trauma (9 cases) in 54 cases (12 cases were confirmed by operation) were imaged with eight different MR imaging sequences including T 1-weighted,proton density-weighted,T 2-weighted FSE,STIR,3D-FS-SPGR,2D-FS-SPGR,3D-SPGR and 3D-FS-GRE.The classification and three-dimensional reconstruction of cartilage in four locations of knee were performed on different MR sequences.The detecting rate of cartilage lesion were calculated.The results in partly cases were analysed compared to operation. Results The detecting rate was different on each sequence as follow:T 1WI,GRE,STIR,PDWI,T 2WI and SPGR were 8.91%,16.36%,19.32%,19.57%,21.36% and 24.09% respectively (? 2=23.523,?
10.Study of microsurgical anatomy and multi-slice helical CT scanning of cochlear aqueduct
Chunlei LU ; Chunlin HUANG ; Xiaoming QI
Medical Journal of Chinese People's Liberation Army 1983;0(02):-
Objective To obtain more detailed microsurgical anatomical data and multi-slice helical CT scanning of cochlear aqueduct for the translabyrithine approach. Methods Twenty cadaver heads(40 sides)fixed with formalin were dissected under a microscope ,and cochlear aqueducts were found and measured. Five cadaver heads(10 sides) were scanned by multi-slice helical CT. Results The width of external aperture of cochlear aqueduct was (2.64?0.82)mm. The length of cochlear aqueduct was (8.40?1.35)mm. The distance between cochlear aqueduct and cranial nerves Ⅸ, Ⅹ, Ⅺ, and that between the inferior petrosal sinus was(1.08?0.36 )mm,(2.71?0.63)mm,(4.52?1.25)mm, (1.14?0.46)mm, respectively. The distance between external aperture of cochlear aqueduct and the inferior margin of internal acoustic meatus aperture was (5.53?0.93)mm. The otic capsule segment of cochlear aqueduct could not be demonstrated on the coronal section. The petrosal portion could be demonstrated by both coronal and axial scannings. Conclusion The axial scanning was useful for detecting cochlear aqueduct. Cochlear aqueduct could be regarded as one of the landmarks in translabyrithine approach for cerebellopontile angle operation.