Circulating microparticles (MPs) derive from a variety of cells,including platelets,leukocytes,endothelial cells and erythrocytes.In addition,tumor cells release MPs into blood.MPs are formed as a result of membrane lipid remodeling and proteolytic cleavage of cytoskeleton.Exposure of phosphatidylserine (PS) and tissue factor (TF) provide a surface for the assembly of Xase and prothrombianse to activate coagulation and induce thrombosis.Considerable levels of platelet-derived PS+ MPs are detected in healthy subjects.However,the level of PS+ and TF+ MPs,the latter of which predominantly derived from monocytes,greatly increased in thrombotic diseases,such as sepsis,cancer,and myocardial infarction.Therefore,MPs could be a useful biomarker for the evaluation of thrombosis risk.

ObjectiveBy reviewing TCM research projects in Nanjing municipal hospitals from 2006 to 2010 (eleventh five-year plan), this study aimed to recognize the existing problems, put forward corresponding solutions, and help Nanjing municipal hospitals improve scientific research level.Methods Through field investigations and interviews with experts, this study set 139 research projects from 2006 to 2010 in 10 municipal hospitals in Nanjing as study samples. ResultsDuring 2006-2010, current situations in TCM research projects of Nanjing municipal hospitals were as follows:the number of TCM research projects was small, the research level was low, and the fund was little. TCM research resources were unevenly distributed;the overall quality of TCM human resources were not high;talent structure was unreasonable;great differences existed among different types of hospitals.ConclusionsDuring the eleventh five-year plan period, there were significant differences between TCM research projects and WM research projects in Nanjing municipal hospitals, such as the differences in number, level, fund and project channel. The study proposed that TCM research materials should be rationally allocated, related mechanisms should be perfected, the industrial structure should be optimized, and the pace of training and introducing TCM research human resources should be quickened, with a purpose of making contributions to TCM development in Nanjing.

Objective To investigate the short and long-term effects of flupentixol-melitracen after percu-taneous coronary intervention( PCI) .Methods 86 patients with coronary heart disease who would be given PCI were randomly divided into 43 cases of the study group and 43 cases of the control group.The control group was given conventional treatment after surgery, the study group was given flupentixol -melitracen on the basis of the control group.After one course,the mental status changes and short-term effect were observed.All the patients had been follow-up for 1 year to observe the occurrence of cardiovascular events.Results After one course,the HAMA and HAMD in the study group and the control group were (7.46 ±2.53) points and (15.74 ±3.16) points,(8.03 ± 1.97)points and (16.42 ±3.67)points respectively,which in the study group were lower than the control group (t=13.413,13.208, all P <0.01 ) .The total effective rate of the study group was 97.67%, which was higher than 81.40%of the control group (χ2 =6.081,P<0.05).During follow-up,the incidence rate of adverse cardiovascular events in the study group was 6.67%,which was lower than 42.86%of the control group (χ2 =9.564,P<0.05). Conclusion The flupentixol-melitracen can effectively improve anxiety and depression, improve the recent thera-peutic effect of PCI,reduce the incidence of cardiovascular events,which worthy of promotion after PCI.

Natural killer (NK) cells,a major cell type of the innate immunity,have a central role in infections,immunizations and tumors.The relationship between NK cells and hematological malignancies is increasingly pursued by domestic and foreign researchers.Exploring the relationship between function and activity of NK cells and malignant hematological disease is of great importance.

Objective To improve pediatric laparoscopic surgical nursing care by establishing and applying standardized management mode, and ensure the operations and the children′s safety. Methods 100 children were respectively selected who received laparoscopic surgery from January to June and from July to December 2015 as control group and test group. Nursing workflow were respectively carried out before and after standardized management mode applied in control group and test group. Then we compared the differences in examination scores, time cost of operative preparation and surgeon satisfaction of specialist nurses between the two groups. Results After the implementation of standardized management, the examination scores of specialist nurses were higher than before. The theoretical and operating scores before implementation were (74.94 ± 2.01) and (81.63 ± 0.92) points, while the scores after implementation were (80.67 ± 3.91) points and (86.22 ± 1.48) points relatively. The differences were statistically significant (t=3.726,7.570, P<0.01);The time cost of operative preparation was significantly shortened from (27.94±1.88) minutes to (23.56±1.61) minutes (t=5.181,P<0.01);In the survey of nurses′satisfaction, the nursing knowledge scores increased from (3.77 ± 0.57) points to (4.17 ± 0.46) points after the implementation, while skill scores lifted from (3.57 ± 0.63) points to (4.00 ± 0.83) points, with all the differences above are statistically significant(t=2.994, 2.282,P < 0.01). The rate of laparoscopic equipment failure was declined, especially the case of equipment failure due to misuse had reduced from 12 to 2 cases (χ2=7.680,P < 0.05). Conclusions Application of standardized management mode can effectively improve the nurses′ professional ability and the rate of normally used equipment in the operation, which improved surgeon′s satisfaction.

Based on translation research and practice, inspired by focus on image regeneration in poetry translation, this paper advocates the same strategy be used in English translation of Traditional Chinese medical classics, introducing the strategy as Image Equivalence, and demonstrating its advantages in improving translation quality of texts like HuangDi Neijing.

Glaucoma is the most common cause of irreversible blindness worldwide.The major performances of glaucoma optic neuropathy are progressive loss of retinal ganglion cells (RGCs),specific visual field defect and optic atrophy induced by elevated intraocular pressure.Glaucoma primarily includes primary open angle glaucoma (POAG),chronic angle-closure glaucoma (CACG) and exfoliation glaucoma (XFG).Recent studies showed that genetic factor and environmental factor participate in the pathogenesis of glaucoma,and the contributions of genetic factor to glaucoma are widely concerned,and some disease-causing gene and their pathogenic mechanisms are sequentially announced.A comprehensive discussion of the advances in molecular genetics of glaucoma is included in this paper.

Objective:To investigate the efficacy of Peibao capsules combined with letrozole in the treatment of ovulatory infertility and its effects on serum sex hormone levels. Methods:Sixty patients with ovulatory infertility who received treatment in Taizhou Cancer Hospital from January 2017 to December 2019 were included in this study. They were randomly assigned to receive treatment with either letrozole (control group, n = 30) or Peibao capsules combined with letrozole (observation group, n = 30) starting at the 5 th day of the menstrual cycle for 5 days, totally 3 menstrual cycles. Before and after treatment, dominant follicle diameter, endometrial thickness, ovarian artery resistance index and pulsatility index, serum sex hormone level, ovulation rate and pregnancy rate were compared between the control and observation groups. Results:After treatment, dominant follicle diameter and endometrial thickness in the observation group were (18.41 ± 0.54) mm and (8.79 ± 0.56) mm, respectively, which were significantly greater than those in the control group [(17.79 ± 0.47) mm and (7.82 ± 0.62) mm, t = 4.744 and 6.359, both P < 0.05]. After treatment, ovarian arterial resistance index and pulsatility index in the observation group were 0.97 ± 0.13 and 0.56 ± 0.04, respectively, which were significantly lower than those in the control group [1.08 ± 0.10 and 0.65 ± 0.04, t = 3.674, 8.714, both P < 0.05]. After treatment, serum progesterone, estradiol and luteinizing hormone in the observation group were (0.93 ± 0.14) μg/L, (75.41 ± 6.29) ng/L and (9.47 ± 0.61) IU/L, respectively, which were significantly higher than those in the control group [(0.78 ± 0.12) μg/L, (58.23 ± 5.46) ng/L and (8.18 ± 0.65) IU/L, t = 4.456, 11.297, 7.926, all P < 0.05]. Ovulation rate and pregnancy rate in the observation group were 60.00% (18/30) and 46.67% (14/30), respectively, which were significantly higher than those in the control group [33.33% (10/30) and 23.33% (7/30), χ 2 = 4.286, 3.897, both P < 0.05). Conclusion:Peibao capsules combined with letrozole is highly effective in the treatment of ovulatory infertility. It can improve patient's serum sex hormone level, promote ovulation, and increase pregnancy rate.

In modern war the multiple wounds caused by projectiles, such as exploded artilery shells, hand grenades and mines, often occured. In the paper the characteristics of the multiple wounds were discussed based on 717 cases of war wounds. The characteristics Included the extensive wounds, high incidence of shock and the blind wounds. The remote effect was often seen in these cases. And also the treatment principles of these wounds were dicussod in this paper.