Objective PRDX-2 of the basic level in patients with PCOS,and its correlation with cardiovascular risk factors.Methods Collected 78 cases of PCOS patients for POCS group,at the same time,choose healthy check-up 40 cases for control group.Determination of plasma Peroxiredoxin-2,blood sugar,glycosylated hemoglobin,cholesterol,triglycerides,and other biochemical indicators.Results Peroxiredoxin-2 level in PCOS group are higher than the control group(F=26.03;P<0.05).Peroxiredoxin-2 and cardiovascular risk factors exist correlation,including systolic blood pressure (r=0.213),diastolic blood pressure (r=0.380),fasting blood glucose (r=0.308),glycosylated hemoglobin (r=0.303),cholesterol (r=0.190),triglyceride (r=0.276),LDL-C (r=0.484) were positively correlated,and CRP (r=0.227),HDL-C negative correlation (r=0.355).Conclusion Determination of Peroxiredoxin-2 level can be used as evaluation of patients with PCOS risk factors for cardiovascular disease.

E-health was referred as the use of internet and ICT ( information and communication technology) for health in this paper, which mainly encompassed electronic health record, online health information and tele-health. The paper summarized the new characteristics of privacy of e-health, and presented current privacy issues raised by these applications. The major privacy concerns were unauthorized access to and secondary use of privacy data. The paper put forward some governance suggestions of privacy protection.

OBJECTIVE: To investigate the perioperative application of antibacterials in our hospital.METHODS: The application of antibacterial drugs in 142 surgery patients sampled randomly from our hospital in 2006 was investigated in respect of the variety of drugs,medication time and drug combination etc.RESULTS: 100% of the total 142 cases received antibacterials for prophylaxis purpose for 6.8 days on average.58 cases(40.8%) received antibacterials before operation,8 cases(5.6%) during operation and 76 cases(53.5%) after operation.35.8% were rational on the whole and 64.2% irrational in drug use.CONCLUSIONS: The application of antibacterials in our hospital is worrisome,therefore,it is urgent to tighten control on the clinical application of antibacterials.

Objective To explore the influence of aerobic exercise on plasma lipoprotein in overweight and obese PCOS women.Methods 12 obese and overweight patients with PCOS were selected.Before and after 12 weeks of aerobic exercise,the height,weight,BMI,WHR,body fat percentage and fasting blood samples of high-density lipoprotein(HDL),low density lipoprotein(VLDL),triglyceride and cholesterol levels were measured and detected.Results After 12 weeks of aerobic exercise,the BMI[(25.43±2.17)kg/cm2 vs.(22.27±1.57)kg/cm2,t=8.52],WHR[(0.864±0.021) vs.(0.831±0.019),t=2.99],fat rate[(33.76±5.36)% vs.(30.53±5.66)%,t=5.580],and triglyceride[(1.90±0.58)mmol/L vs.(0.95±0.51)mmol/L,t=7.400]were obviously decreased,the high-density lipoprotein cholesterol[(2.07±0.39)mmol/L vs.(3.31±0.48)mmol/L,t=3.352]was obviously increased,the differences were statistically significant (all P<0.05).Conclusion Obese and overweight PCOS women can lose weight through aerobic exercise,so as to adjust lipoprotein spectrum and improve health.

Objective To investigate the the expression of soluble Fas (sFas) in the placenta of pregnancy induced hypertension (PIH) patients after perinatal. Methods Expression of sFas were detected by Fluorescent MGB Probe Real-Time PCR in 34 severe PIH patients and 30 healthy pregnant women served as normal controls.Results Expression of placenta sFas in 34 patients were significantly higher than those in normal controls.Conclusion PIH patients' placenta had higher expressiom of sFas; Detection of sFas may be helpful to value PIH degrade and sFas would be become a indicative markers of cell proliferation and apoptosis during the perinatal period.

Objective To investigate the kindergarten weigh recipe nutrients allowance and chidren health status.Methods The dietary analysis was made in kindergartens by weighing and growth development was perfonmed in 17 947 chidren.Results The nutrients allowance was different in 15 observation projects,recipe nutrients allow-ance was sufficient for 80%,nutrients allowance was not enough for 20%.Middle serious malnutrition was 0.62%,slow gowth and development was 0.67%.simpie obesity was 5.80%.anemia was 1.40%.Conclusions The recipe nutrients allowance was difference in all kindergartens.Nutrients abundant and not enough was concurrent.Simple o-besity incidence rate was much higher than middle serious malnutrition.

Purpose:To detect the expression of MDR 1 / P-gp,C-erbB-2 in breast cancer and study the correlation between MDR 1 /P-gp and C-erbB-2. Methods:Expression of MDR 1 gene was measured with the flu orogenic quantitative RT-PCR method in 57 cases of breast cancer and 20 cases o f control group (including 10 cases of benign breast lesions and 10 cases of adj acent breast tissues). In addition, immunohistochemical analyses was used to det ect the expression of P-gp and C-erbB-2 protein in the above mentioned tissu es. Results:The amplification rate of MDR 1 gene and the expre ssion of P-gp protein in breast cancer group was 50.88% (29/57) and 42.11% (24/ 57), which had a significient difference as compared to the control group. The a mplification of MDR 1 gene were higher than the expression of P-gp protein ,there was close correlation between them but not complete correspondence.The p ositive rate was 28.07%(16/57) in detecting the overexpression of C-erbB-2 pro tein in breast cancer group, nevertheless, no positive case was found in the con trol group. The expression of MDR 1/P-gp was also correlated with the over expression of C-erbB-2. Conclusions:Multidrug resistance gene1(MDR 1)and protoonco gene C-erbB-2 were co-expressed in breast cancer,and their expression were po sitively related. The expression of above mentioned two genes have a relationshi p with multidrug resistance in breast cancer.

Objective To study cyclooxygenase-2 (COX-2) expression levels in cervical, endometrial and ovarian cancers as well as their originated normal tissues. Methods Semiquantitative immunofluorescent assay (IFA) was used to detect COX-2 expression levels in cervical squamous cell carcinoma (n=12),endometrial adenocarcinoma (n=13),and ovarian serous adenocarcinoma (n=9). COX-2 expression levels in normal cervical (n=14),endometrial (n=15),and ovarian (n=13) tissues were simultaneously detected as control. Results Normal cervical tissues expressed COX-2 more frequently than cervical cancers (50% vs 23%), but the difference was not signicant (P=0.247). The positive rate of COX-2 expression was significantly higher in endometrial adenocarcinomas (69%) than that in normal endometrium (7%) (P

Objective To assess the role of matrix metalloproteinase-9(MMP-9) and interleukin-6 (IL-6) of amniotic fluid (AF) in predicting infection of amniotic cavity. Methods Eighty-four cases of sigle foetus women with premature delivery, premature rupture of foetal membranes,or suspicious infection of amnitotic cavity were enrolled in this study. AF was obtained by transabdominal amniocentesis before starting any treatment.Infection of amniotic cavity was defined when AF bacterial culture was positive. The contents of glucose, leukocytes, MMP-9,and IF-6 in AF were determined. Results The levels of MMP-9 and IL-6 in AF were significantly higher in women with infection of amniotic cavity than those in women without. In women with infection of amniotic cavity, MMP-9 level was significantly correlated with IL-6 level (r=0.813,P

Objective To study the safety of hypothermia in neonates with hypoxic-ischemic brain damage after asphyxia. Methods Twenty four full term newborns with Apgar score 0.05). Conclusions The results suggest that the selective head cooling in full term newborn has no significant adverse effect on cardiac function, kidney function and coagulation function.