1.Spectral entropy analysis of different alpha band rhythms in relation to hand motor imagery
Xiaomei PEI ; Chongxun ZHENG ; Renhou LI
Journal of Pharmaceutical Analysis 2008;20(3):202-205
The event-related desynchronization/synchronization(ERD/ERS) time courses of lower and upper alpha band rhythms during hand motor imagery are investigated respectively by Fourier Sectral Entropy (FSE) in this paper. By analyzing one group of BCI competition data, it was found that FSE within upper alpha band displays a pronounced increase and decrease over contralateral and ipsilaterai brain areas respectively at the onset of hand motor imagery, which is corresponding to the antagonistic ERD/ERS patterns in previous studies. Different from the upper alpha activity pattern, FSE within lower alpha band displays a consistent increase over both two hemispheres hand representative areas. The preliminary results show that FSE could disclose the different behaviors of the upper and lower alpha band rhythms so that a new idea with the complexity measure is provided to characterize functional dissociation of lower and upper frequency alpha rhythms in relation to hand motor imagery.
2.Effects of different techniques on removal of vapor lock in the apical region of curved canals: a cone-beam computed tomography study
Zheng SU ; Yuhao BAI ; Xiaomei HOU
Journal of Peking University(Health Sciences) 2017;49(1):76-80
Objective:To compare the effect of four different techniques on removal of vapor lock in the apical region of curved root canals.Methods:Forty simulated resin root canals with 45° curvature were prepared using WaveOne Primary,then the apical foramen were sealed with soft wax.The teeth were divided randomly into 4 groups thereafter (n =10).Contract solution was injected into the canals using a 30 G side-vented needle and scanned with cone-beam CT (CBCT) to identify the volume of the vapor lock.Four different techniques including photon-induced photoacoustic streaming (PIPS) laser-activated irrigation,gutta-percha cone technique,ultrasonic irrigation,and sonic irrigation were used to remove the vapor locks in the root canals.The residual volume of the vapor lock was identified again using CBCT scanning data.Accordingly,the reduction rates of the vapor lock were calculated.Furthermore,the initial and residual vapor lock length was calculated.The data were analyzed by using the One-Way ANOVA analysis and Kruskal-Wallis H test at a significance level of P < 0.05.Results:There was no significant difference in the initial vapor lock volume (P > 0.05).Residual volume of the vapor lock for PIPS laser-activated irrigation was 0 mm3,and that for gutta-percha cone technique was (0.02 ± 0.07) mm3,significantly lower than those of ultrasonic and sonic irrigation,the values being (0.20 ± 0.09)mm3 and (0.23 ±0.06) mm3 (P <0.001),respectively.The reduction rates of the vapor lock of PIPS laser-activated irrigation and gutta-percha cone technique were 100.00% (100.00%,100.00%) and 100.00% (77.66%,100.00%),respectively,significantly higher than those of ultrasonic irrigation [70.37% (56.41%,91.43%)] and sonic irrigation [63.54% (51.47%,74.00%),P <0.001].The length of the residual vapor lock for PIPS laser-activated irrigation was 0 mm,and that for gutta-percha cone technique was (0.15 ±0.47) mm,significantly lower than those of ultrasonic and sonic irrigation,values being (2.21 ±0.09) mm and (2.34 ±0.08) mm (P <0.001),respectively.The length of the residual vapor locks in the ultrasonic and sonic group remained approximately the same as the distance between the working tip and the apical foramen.Conclusion:PIPS laser activated irrigation and gutta-percha cone technique could remove the vapor lock from the apical region of curved canals effectivelv.
3.Observations on the Therapeutic Effect of Herbal Cake Moxibustion on Chronic Renal Failure
Zheng ZUO ; Zunxin GUAN ; Xiaomei CHENG
Shanghai Journal of Acupuncture and Moxibustion 2015;(3):218-220
Objective To investigate the clinical efficacy of herbal cake moxibustion in treating chronic renal failure. Methods Sixty CRF patients were randomly allocated to treatment and control groups, 30 cases each. The control group received medication and diet control and the treatment group, herbal cake moxibustion on Shenshu, Pishu or Ganshu in addition. Pre-/post-treatment differences in serum creatinine (Scr), blood urea nitrogen (BUN), endogenous creatinine clearance rate (Ccr) and 24-h urinary protein quantity were observed in the two groups and the clinical therapeutic effects were compared between the two groups after 3 months of treatment.Results The marked efficacy rate and the total efficacy rate were 46.7% and 86.7%, respectively, in the treatment group and 20.0% and 46.6%, respectively, in the control group, and there were statistically significant differences in both between the two groups (P<0.05). There were statistically significant pre-/post-treatment differences in Scr, BUN, Ccr and 24-h urinary protein quantity in the two groups (P<0.05). There were statistically significant post-treatment differences in Scr, BUN and 24-h urinary protein quantity between the treatment and control groups (P<0.05).Conclusion Herbal cake moxibustion is an effective way to treat chronic renal failure.
4.A Study on Status Analysis and Strategies of Society Public’s Satisfaction Regarding the Grass-roots’TCM Work in Our Province
Binyan WANG ; Liu ZHENG ; Xiaomei WANG
Journal of Zhejiang Chinese Medical University 2015;(3):232-235
Objective] The study analyzes the current situation of public’s satisfaction and expectation on the grass-roots’work of TCM in our province to make advice on improvement. [Method] From the perspective of service objects, combining with satisfaction theory and using the method of random surveys, the article does the researches on the publics’satisfactions and expectations on 24 projects related to the grass-roots levels of TCM and puts forward corresponding countermeasure against those problems. [Consequence] The degree of satisfaction ranges from 65 to 72, average is 68.685; the highest degree of satisfaction is the therapeutic effects of TCM, but the lowest one is medical costs. The degree of expectation ranges from 79~86, average is 83.931, the highest degree of satisfaction is diagnostic reference level of medical staff from the grass-roots ’work of TCM, the lowest one is characteristic service projects of TCM. [Conclusion] The study analyzes and evaluates the grass-roots ’work of TCM by the related theory of satisfaction, having significant meaning on improving the management services’level of the grass-roots’work and the performance evaluation of government.
6.Exploration of ophthalmology practice teaching for foreign students majoring in clinical medicine
Ke ZHENG ; Xiaoying WANG ; Xiaomei QU ; Xingtao ZHOU
Chinese Journal of Medical Education Research 2014;(6):605-607
Ophthalmology belongs to microsurgical subject and anatomy is intricate. In clinical practice, students are required to skillfully use eye examination equipment. The foreign students from Medical School of Vienna University are eager to learn and know theoretical knowledge very well. Department of ophthalmology has developed specific and individualized teaching plans according to the characteristics and needs of foreign students. Through the configuration of high quality teachers, the practice teaching is ensured. Chinese and foreign students are encouraged to share their knowledge and form a study group. Opportunities for hands-on practice of ophthalmology are increased by using Wetlab condition. Problem-based heuristic teaching is used to stimulate students' learning initiative. Through these teaching measures, the students' quality of clinical practice has been enhanced, the teaching level of clinical ophthalmology has been improved and sustainable development has also been achieved.
8.Preliminary Investigation of Imaging Parameters on Optimizing Low Field MRCP
Shengde DENG ; Ming WEI ; Shengxi ZHENG ; Xiaomei YAN
Journal of Practical Radiology 2001;0(07):-
Objective To investigate imaging parameters on low field MRCP and to optimize the quality of images.Methods MRCP in 77 cases were performed using Airis-Ⅱcomfort open 0.3T low field MR imaging system made by HITACHI company.3D-FSE combined with 2D single-shot breath-hold FSE sequences were used.The 3%~5% compound solution of Gd-DTPA was taken to restrain the hige signals from remaining liquid in stomach.Results MRCP examination was succeeded in all 77 cases and the images in all cases but 2 were fine for diagnosis.The total diagnostic accuracy was 79.2%.The accuracy of MRCP in the detection of the degree and location of pancreaticobiliary duct obstruction was 100%. Conclusion The distinct MRCP images can be obtained with low field MR system using combination of several scanning techniques and proper scanning parameters,and also patients have to prepare fully.
9.Study on expression level of proto-oncogene Wip1 in endometrial carcinoma tissue
Xiaomei GU ; Juan LI ; Shufeng GAO ; Wei ZHENG ; Hao ZHANG
International Journal of Laboratory Medicine 2017;38(16):2210-2212,2215
Objective To investigate the related factors of clinical stage and prognosis in the patients with endometrial carcinoma and their relation with proto-oncogene Wip1 expression level.Methods The paraffin samples of resected endometrial carcinoma in 120 cases of endometrial carcinoma in our hospital from January 2002 to January 2012 were collected as the experimental group,the samples were verified by pathology.Contemporaneous 120 samples of biopsy normal endometrial tissue served as the control group.The expression leve of Wipl were detected in turo groups.Results (1) In the Wip1 immunohistochemical staining results:Wip1 immunohistochemical staining was negative or weak in normal endometrial tissue cells,while showed pale yellow to yellowish-brown in endometrial cancer tissue.The positive expression rate of Wip1 protein in endometrial carcinoma tissue was 77.5%(93/120),which was higher than 22.5%(27/120) in normal endometrial tissue,the difference was statistically significant (P<0.05).(2)In the Western blot results of Wip1 protein in endometrial cancer tissue and normal endometrial tissue:the relative amount of Wip1 protein in endometrial carcinoma tissue was 0.635±0.023,which was significantly higher than 0.325±0.018 in normal endometrial tissue,the difference between the two groups was statistically significant (P<0.05).(3)In the real time quantitative qRT-PCR results of various samples:Wip1 mRNA expression level was higher than that in normal endometrial tissue,which were 0.628±0.053 and 0.191±0.009 respectively,the difference between the two groups was statistically significant(P<0.05).(4) The expression level of Wip1 had no correlation with age,estrogen and progesterone status,HER2,lymph node status and TNM stage,but had correlation with P53 expression level.Conclusion (1) The Wip1 expression amount is high in endometrial carcinoma and low in normal endometrial tissue.(2)The Wip1 expression level has no relation with age,estrogen and progesterone status,HER2,lymph node status and TNM stage,while has association with P53 expression level.
10.The construction of natural drugs curriculum system in the process of pharmacy talentstraining
Guane YANG ; Qinghong ZHENG ; Xiaomei QI ; Jianping GAO ; Qingshan LI
Chinese Journal of Medical Education Research 2011;10(12):1440-1442
On the basis of analyzing the transition and development trend of current medical and pharmaceutical mode,this article proposed that in the process of pharmacy talents training,not only biological,but also the construction of natural drugs knowledge should be stressed.In addition,the necessity of natural drugs knowledge construction as well as its practice and future blueprint in our university were illuminated intensively,in order to provide reference for the training of pharmacy talents in local colleges.