Helicobacter pylori(Hp)infection is the cause of a variety of gastrointestinal disease. Currently,there are many therapeutic regimens for Hp eradication,however,because of the increase of Hp resistance and adverse effects in the treatment,the eradication rate of Hp is not very satisfactory. Studies showed that probiotics as an adjuvant may improve the eradication rate and reduce the incidence of adverse effects in eradication therapy for Hp. This article reviewed the advances in study on application of probiotics in eradication of Hp.

Interventional treatment provides another option for patients with ischemic cerebral vascular disease. It has been accepted by doctors and patients for its miniinvasive and good effect. The doctors performing the operations scatter in different departments, therefore they have different special professional opinions about the diagnosis and treatment, outcoming with deviation form the proper treatment indications. Revising treatment notion with special emphasis on the brain function improvement, standardized operation and strict discipline are urgently needed for the promising management and development with combination of the new comprehensive knowledge and concepts, especially follow the time indications.

ve To explore a method for determination of magnesium in drinking water by air-acetylene flame atomic emission spectrometry. Methods The content of magnesium in drinking water was directly determined by air-acetylene flame atomic emission spectrometry using hydrochloric acid as media and lanthanum solution as masking agent. Results The concentrations of magnesium in drinking water were possitively correlated with the intensities of flame atomic emission spectrum in the range of 5~200?g/ml with a regression equation of A = 0.000 87C+0.0019(r=0.992 2). The detection limit was 5.0?g/ml. The recovery rates of a standard material added-water samples were 101.8% ~ 107.5% . The relative standard deviation was not more than 3.3% . The com-monly coexisting ions with a certain concentrations, such as K, Na, Ca, Zn, Fe, Mn, Cd,Pb and Cu, didn't interfere the determination of magnesium in water sample. Conclusion This method could be applied to determination of magne-sium in drinking water.

It has been a sub - rale in hospital that many doctors and hospitals themselves try every means to get maxinoum interests from patients in many places. Througyh the " Hu Wei Min" case, this essay analyzed the reasons and drawbacks of asking extra money from patients and discussed related social ethical problems and therefore brings out a counter - plans to solue the problem.

OBJECTIVE:To discuss the effect of recombinant human growth hormone(HGH)on serum sndotoxin,inflamma-tory cytokines,wound healing time,hospitalization time and prognosis of elderly patients with severe burn. METHODS:96 elder-ly patients with severe burn in our hospital were randomly divided into treatment group (48 cases) and control group (48 cases). All patients received wound surface care,nutritional support,maintaining water and electrolyte and acid-base balance. Control group received 1 ml 0.9% Sodium chloride solution,sc,qd. Treatment group received 0.3 IU/kg. Recombinant HGH for injection, sc,qd. All patients were treated for 21 d. Serum endotoxin content in 2 groups before and 14,21 d after treatment was compared, inflammatory cytokines (TNF-α,IL-6, IL-8) before and after treatment,wound healing time,hospitalization time and the inci-dence of multiple organ disorder syndrome(MODS),death and systemic infection were observed. RESULTS:There was no signifi-cant difference in serum endotoxin content before and 14 d after treatment(P>0.05);after 21 d,serum endotoxin contents in 2 group obviously decreased,and treatment group was significantly lower than control group,with statistical significance(P<0.05). After treatment,IL-8 level in treatment group was significantly higher than control group,TNF-α and IL-6 were significantly lower than control group,with statistical significances (P<0.05). Wound healing time and hospitalization time in treatment group were significantly shorten than control group,with statistical significances(P<0.05). The incidence of MODS,death and systemic infec-tion in treatment group were significantly lower than control group,with statistical significances(P<0.05). CONCLUSIONS:The application of recombinant HGH in elderly patients with severe burn can reduce toxins absorption of patients and decrease inflamma-tory cytokines to promote wound healing and improve prognosis.

Objective To assess the reliability and validity of standardized facial photographs under natural head position (NHP) in assessment of mandibular asymmetry cases. Methods Standardized facial photographs (SFP) and posteroanterior cephalometry (PAC) were taken under natural head position from 25 mandibular asymmetry eases (14 boys and 11 girls), aged 14 to 29 years old. Distances from 8 landmarks to the vertical reference line were measured. The difference and the asymmetry ratio of two sides were calculated respectively. The relationship between the measurements of SFP and PAC were compared, and the repeatability of landmarks was assessed. Results Six measurements were significant different between two sides, 3 from SFP and 3 from PAC. Measurements from two ways were correlated a cer-tain extent. The repeatability of landmarks was satisfied. Conclusion Measurements from standardized facial photographs under NHP pres-ent a clinical useful method to quantify mandibular asymmetry.

Objective To discuss the value of mammotome biopsy of breast cakified lesions under the real time guidance of mammography.Methods The data of 42 patients with 44 mammary gland calcification(2 patients with bilateral lesions)who underwent mammotome biopsy under the real time guidance of a mammography from Jan.2011 to Feb.2012 in the First Affiliated Hospital of Chongqing Medical University were retrospective analyzed.Rapid paraffin pathology was conducted.Results Among the 44 lesions,34 were benign(27 hyperplasia,2 fibroadenoma,1 lipoma,1 cyst,3 others)and 10 were breast cancer(a benign lesion diagnosed as breast cancer by postoperative biopsy was included).Among the 42 patients,32 patients had benign lesions,accounting for 76.2％ (32/42),10 patients had breast cancer,accounting for 23.8％ (10/42).All lesions were completely resected during the operation.Malignant lesions were given treatment such as modified radical mastectomy,breast conservation surgergery,chemotherapy and so on.A single lesion resection took about 20 minutes.During the follow-up of 3 months,no significant event happened.Conclusions Through the qualitative diagnosis of mammotome biopsy under the real time guidance of mammography,we can get early diagnosis of breast cancer.Early diagnosis and early treatment can improve the life quality and survival time.It is more important to detect early breast cancer which was considered benign lesions clinically.Mammotome biopsy under the real time guidance of mammography has several advantages including easy to operate,accurate positioning and less complications,making it the preferred approach in managing mammary gland calcification especially suspicious malignant calcification.

Objective To study the change of neurohormonal factors during CABG and find the effective perioperative treatments for coronary artery disease patients with high-risks. Methods Forty-eight patients were divided into on-pump CABG group(group A, n=23) and off-pump CABG group(group B, n=25). The clinical results were observed and blood samples were collected at six time-points. Angiotensin II(AG II), aldosterone(ALD), atrial natriuretic peptide (ANP), insulin, glucose and cTnI levels in plasma were measured respectively. Results The AG II levels in plasma increased in both groups and reached the peak at 6 h after operation in group A and 3 h after operation in group B, respectively. The peak level of ALD in plasma were at 6 h in group A, and 0 h in group B. The level of ANP in plasma was highest at 0 h in group A, and at the midoperation in group B. The insulin level in plasma was highest at 24 h in group A and at 6 h in group B. The insulin level at 24 h in group A was significantly higher than that in group B. The glucose level reached the peak at 3 h after operation in group A and at 0 h after operation in group B. The levels of AG II, ALD, ANP and glucose in plasma in group A were significantly higher than those in group B at any time-point. The cTnI levels were highest at 24 h in both groups. The cTnI levels in group A were significantly higher than group B at time-points. Conclusion CABG can produce hyperosmotic urinative effects and hyperaldosteronism, which in CABG group is strong and persistent effects due to the hyperosmotic urinative effects and hyperaldosteronism. In OPCAB group is light and short urinative effects mainly due to the hyperosmotic. ACEI, ARB and aldosterone antagonists should be used during the perioperation of CABG. During the early postoperative period, the plasma glucose should be well controlled and GIK solution with magnesium is needed.

Objective To explore the changes of CRP,IL-6,and IL-10 levels after laparoscopic or open repair of inguinal hernia in children.Methods Fifty children with inguinal hernia were randomly assigned to laparoscopic repair or open surgery groups(25 in each).In the laparoscopic group(LS group),the hernia sac was closed by ligating the inner ring,while in the open surgery group(OS group),high ligation was performed.The peripheral blood samples of the two groups were collected one day before,immediately after,and one day after the operations.ELISA was used to detect the levels of CRP,IL-6,and IL-10.Results In both the groups,the levels of CRP,IL-6,and IL-10 were significantly increased immediately after the surgeries(LS Group:q=8.508,11.307,and 22.111,P0.05),while in the OS group,the levels remained significantly higher(q=3.845,10.599,and 11.379,P

Objective To compare the artery function of male and female of all age groups in healthy Shenyang population . Methods By using CVProfilor DO 2020,we measured non-invasively the large artery elasticity index (C1) and small artery elasticity index (C2) of male and female of all age groups in healthy Shenyang population. Results CVProfilor DO-2020 showed C1 was obviously higher than C2 in healthy Shenyang population(P0 05);The results of a second DO-2020 measurement had no significant difference in short term. Conclusion The large artery elasticity was obviously higher than that of small artery.The elasticity of both large and small artery decreased with increasing age .The large artery elasticity of females is a little lower than that of males .There is no difference in small artery elasticity between the male and female.DO-2020 measuring repeated stably.