1.Investigation about ability of clinical decision-making among nursing undergraduates
Chinese Journal of Practical Nursing 2010;26(2):19-21
Objective To explore the present state of clinical decision-making ability of nursing students in Sichuan Province. Methods The instrument for measuring the clinical decision-making ability of nursing students was adopted te investigate baccalaureate nursing students from four colleges and uni-versifies in Sichuan Province who had completed 10-12-month clinical practice. Results The overall mean score of clinical decision-making ability of baccalaureate nursing students in Sichuan Province was (72.86± 4.53). Among the dimensions, the scoring rate of Goal-setting Ability Dimension was the highest and that of evaluation-feedback ability dimension the lowest. In terms of the qualification rate of clinical decision-making ability, 99.52% of the students were qualified (4.82% good and 94.7% passed) and 0.48% was unqualified. Conclusions Baccalaureate nursing students in Sichuan Province have not showed a high level in clinical nursing decision-making ability and most of them are just qualified. No students have reached the level of excellence.
2.Effect of fluvastatin on the expression of oxidized low-density lipoprotein-1 in human umbilical vein endothelial cells
Xiaolian ZHANG ; Deqian JIANG ; Shebing ZHANG
Chinese Journal of Tissue Engineering Research 2007;0(15):-
BACKGROUND:Oxidized low-density lipoprotein(ox-LDL) is recognized as the essential condition for atherosclerosis.As the ox-LDL-specific receptor,oxidized low-density lipoprotein receptor-1(LOX-1) involved in vascular inflammation and plaques develop-ment of the process.OBJECTIVE:To investigate the effect of fluvastatin on the expression of LOX-1 in human umbilical vein endothelial cells(HUVECs) induced by ox-LDL.DESIGN,TIME AND SETTING:The comparative observation was completed in the Medical Center of Second Xiangya Hospital,Central South University between August 2006 and May 2007.MATERIALS:Human umbilical vein endothelial cell line was purchased from the America ATCC Company.Fluvastatin original powder was supplied by Beijing Novartis Pharmaceutical Co.,Ltd.METHODS:HUVECs were incubated with:①Stimulation by ox-LDL with end concentration of 25,50,100 mg/L.②LOX-1 neutralizing antibody,and interfered with 50 mg/L ox-LDL.③Interfered with nuclear factor-?B(NF-?B) blockers pyrrolidine dithiocarbamate(PDTC),followed by 50 mg/L ox-LDL intervention.④Fluvastatin with concentration of 0.01,0.1,1 ?mol/L were used to interfere the cells,followed by 50 mg/L ox-LDL intervention.⑤There was an blank group as the control.MAIN OUTCOME MEASURES:The expression of LOX-1 mRNA level was detected by RT-PCR.RESULTS:The levels of mRNA of LOX-1 were increased after cells had beenwere incubated with different concertrations of ox-LDL,when compared with the control group.Within the dosage range of 25 to 50 mg/L,the above-mentioned indexes significantly changed in a concentration-dependent manner(P
3.Psychological Distress and Health-related Quality of Life in Relocated and Nonrelocated Older Survivors after the 2008 Sichuan Earthquake.
Xiaoyi CAO ; Lin CHEN ; Lang TIAN ; Xiaolian JIANG
Asian Nursing Research 2015;9(4):271-277
PURPOSE: The purposes of the study were to examine psychological distress and health-related quality of life (HRQoL) in relocated and nonrelocated survivors aged 60 years and older, and to analyze predictors for psychological distress and HRQoL in older survivors 5 years after the 2008 Sichuan earthquake. METHODS: This was a cross-sectional descriptive study with 112 relocated older survivors and 156 nonrelocated older survivors. Our study used a multistage sampling method. The measurements used in the study included self-reporting questionnaire-20, medical outcomes study 36-item short form health survey, and an instrument measuring demographic and disaster-related characteristics. Descriptive and multiple linear regression analysis were performed to determine factors that contributed to psychological distress and HRQoL. RESULTS: The prevalence of psychological distress in relocated group (20.5%) was significantly higher compared to those in nonrelocated group (4.8%). Scores for HRQoL in relocated older survivors was significantly lower than those in nonrelocated older survivors. Relocation from preearthquake residence was the most significant predictor for psychological distress and HRQoL in the total sample. Other predictors were advanced age, lower educational level, the loss of family members during the earthquake, and the presence of chronic illnesses as well as the death of a spouse after the earthquake. CONCLUSIONS: Strategies can be designed in postdisaster recovery program, particularly for older survivors at high risk for psychological distress and poor HRQoL.
*Adaptation, Psychological
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Age Factors
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Aged
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Aged, 80 and over
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China/epidemiology
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Cross-Sectional Studies
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Disasters
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*Earthquakes
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Female
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*Health Status
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Humans
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Male
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Middle Aged
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Prevalence
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Quality of Life/*psychology
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*Residence Characteristics
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Socioeconomic Factors
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Stress, Psychological/*epidemiology
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Surveys and Questionnaires
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Survivors/*psychology
4.Development and Application of Permanent Magnet Motor and Its Control in the Field of Artificial Blood Pump.
Chinese Journal of Medical Instrumentation 2019;43(5):355-358
Permanent magnet motor has been widely used in the field of artificial heart pump due to its high power density, high stability and easy control. In this paper, the development history and research progress of permanent magnet motor for blood pump were described. Firstly, the motors were classified according to their structures and application scenarios. And then, the measures taken by different types of motors to meet the corresponding performance requirements were introduced, and the specific application cases were given. After that, commonly used control algorithms of these motors were enumerated. What's more, the advantages and disadvantages of the control algorithms and their application emphasis were carefully explained. Finally, the paper was summarized in short.
Algorithms
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Blood Substitutes
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Heart, Artificial
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Magnetics
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Magnets
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Prosthesis Design
5.Study on current staffmg of nurses and need of hospital nursing human resources in China
Ying XU ; Liming YOU ; Ke LIU ; Huaping LIU ; Xiaomei LI ; Xiaohan LI ; Guoping HE ; Shaomei SHANG ; Yan HU ; Xiaolian JIANG ; Jun YAN ; Jing ZHENG ; Xiaowen ZHU
Chinese Journal of Practical Nursing 2011;(31):1-5
Objective To investigate the current staffing of nurses and need of hospital nursing human resources in China.Methods Data were collected from 181 secondary and tertiary hospitals and 9774 nurses in mainland China by questionnaires.Results The average doctor-nurse ratio was 1 ∶ 1.39 in tertiary hospitals and 1 ∶ 1.31 in secondary hospitals.The doctor-nurse ratios in 164 hospitals (97.6%) and the proportion of nurses in health care staff in 105 hospitals (61.8%) had not reached the standard set by the Ministry of Health of China.62.3% nurses held secondary diploma for their initial nursing education.The constituent ratio of nurses held secondary diploma decreased,while the ratio of nurses held advanced diploma and bachelor degree increased in the last 5 years from 2003 to 2007.Sixty percent of newly employed nurses were contract nurses in 2003.The proportion increased to 78% in 2007,and in some regions it accounted for more than 90% of new nurses.The needs and constituent ratio of nurses with.secondary diploma and advanced diploma would decrease while nurses with bachelor degree and master degree would increase in the next 5 years (from 2009 to 2013).Conclusions The nursing shortage is still severe in China,and nursing staff mainly held secondary diploma for their initial nursing education.Most of new nurses were employed as conwact nurses.The need of hospitals for nurses has increased,especially for nurses with higher educational level such as bachelor degree and master degree,while the need for secondary diploma hold ers have decreased.The need for advanced diploma holders has increased in the last 5 years and would decrease in the next 5 years,but they would still be the majority of employed nurses.The authors suggested that the staffing of nursing manpower,the work environments and career development of contract nurses should be improved,and the initial nursing education should be upgraded to meet the needs of hospitals.
6.Effect of families synchronous health education on compliance with intermittent catheterization in ;patients with spinal cord injury and bladder voiding dysfunction
Hong ZHANG ; Zhili LIU ; Xiaolian LI ; Yingqiong CHEN ; Bizhu JIANG
Chinese Journal of Modern Nursing 2016;22(23):3334-3338
Objective To explore the applied effect of families synchronous health education on compliance with intermittent catheterization in patients with spinal cord injury and bladder voiding dysfunction. Methods A total of 60 patients with spinal cord injury caused bladder voiding dysfunction were randomly divided into observation group and control group in admitted chronological order. Patients in control group were given routine nursing; experimental group on the basis of conventional nursing, were applied families synchronous health education throughout the whole process of hospitalization and discharge follow-up. After 30 and 60 days′ self-intermittent catheterization, two groups′ urinary tract management of cognition, satisfaction, compliance and complications were observed and statistically analyzed. Results After 30 and 60 days′ self-intermittent catheterization, the observation group′ urinary tract management of cognition and satisfaction score were higher than those of the control group( P<0.01) . About the compliance, on the 30th day, two groups′urethral catheterization in time, volume of water intake, correctly evaluation residual urine volume and correctly bladder function training had no statistically difference ( P>0. 05); the observation group′s properly adjusting time and correctly operation of urethral catheterization was higher than the control group(P<0.05); on the 60th day, all kinds of aspects of observation group were better than the control group( P<0.05) . About the complication, on the 30th day, the urinary infection rate of observation group was lower than that of the control group( P<0.05);there were no difference on the rate of cystolith and urinary mucosa bleeding of two groups( P>0.05);on the 60th day, the rate of cystolith and urinary mucosa bleeding of the observation group were lower than those of the control group ( P<0. 05 ); two groups′ incidence of bladder calculi had no difference ( P>0. 05 ) . Conclusions Families synchronous health education actively, can improve the compliance of patients with intermittent catheterization and reduce related complications, thus improve the patients′satisfaction.
7.Effects of different developmental patterns on thyroid morphological changes among children in pre-puberty and puberty
Chinese Journal of School Health 2019;40(10):1521-1525
Objective:
To investigate the effects of different developmental patterns on the increases of thyroid volume in children from different genders and periods, and to explore whether there is a synergistic effect on the initiation of puberty in girls, so as to provide a theoretical basis for reducing the risk of thyroid abnormalities in adulthood.
Methods:
A multi-stage cluster sampling was used to select a primary school in Minhang District of Shanghai, Haimen City of Jiangsu Province and Yuhuan city of Zhejiang Province. A total of 784 children aged 8-10 years old were included in "8-10 years school-aged children cohort". At the same time, a total of 491 girls aged 11-13 years were included in the "11-13 years adolescent girls cohort". The content of survey on follow-up was consistent with the one on baseline. B-ultrasonography was used to measure thyroid volume. The physical development indexes such as height (H), weight (W) and waist circumference (WC) were measured. The morning urine samples were collected and the urinary iodine content was detected. The changes of body mass index (BMI), waist circumference (WC), and thyroid volume (V) were calculated (d BMI, d WC, and d V, respectively). According to the changes of BMI and WC, the subjects were classified into four types of developmental changes, namely "B-LW-L (low d BMI, low d WC)" "B-LW-H (low d BMI, high d WC)" "B-HW-L (high d BMI, low d WC)" and "B-HW-H (high d BMI , high d WC)". Results In partial correlation analysis, thyroid volume was significantly correlated with BMI and WC at baseline or follow-up(P<0.05). The changes of thyroid volume in 8-10 years old boys were related to the changes of BMI and WC (P<0.05), the changes of thyroid volume in 8-10 year old girls were only associated with the changes of WC (P=0.03), and no association was found in 11-13 year old girls(P>0.05). In multivariate logistic regression analysis, after adjusting for baseline age, region, and differences of urinary iodine, the risk of thyroid volume increasing in B-HW-H was 2.70 times (95%CI=1.29-5.66) higher than that of B-LW-L in boys aged 8-10 years; among girls aged 11-13 years, the risk of thyroid volume increasing in B-LW-H, B-HW-L and B-HW-H were 2.46 times (95%CI=1.31-4.61), 2.16 times (95%CI=1.15-4.03) and 1.79 times (95%CI=1.07-2.99), respectively; there was no interaction between menarche age and developmental pattern on thyroid volume change trend (P=0.49).
Conclusion
The thyroid volume in children and adolescents increases with the development of physical development. Different developmental patterns and estrogens have certain effects on thyroid morphological changes. To avoid obesity in childhood (especially with central obesity), timely identify and effectively intervene thyroid morphological abnormalities in childhood,and to reduce the risk of thyroid diseases in adulthood.
8.Association between puberty with thyroid morphology and function in women
Yingying WANG ; Qian XU ; Dongli XU ; Xiaolian DONG ; Meifang SU ; Junhua QIAN ; Feng JIANG ; Chaowei FU ; Qingwu JIANG ; Na WANG
Chinese Journal of Epidemiology 2020;41(6):877-883
Objective:To explore the effects of different puberty development stages on thyroid morphology and function in women.Methods:From October to November 2017, a multi-stage cluster sampling method was used to select one junior high school in Minhang district of Shanghai, Haimen city of Jiangsu province, Yuhuan city of Zhejiang province and Deqing county of Zhejiang province respectively. A total of 491 girls in the first grade in 4 schools were included in the study. The subjects were examined with thyroid B-ultrasound and physical examination, and their morning random urine samples and fasting blood samples were collected to detect urinary iodine and thyroid function indexes. Puberty Development Self-rating Scale (PDS) was used to evaluate the stages of puberty; multiple linear regression models and logistic regression models were used to investigate the effects of different puberty stages on thyroid morphology and function.Results:There were differences in thyroid status among women at different stages of puberty. Thyroid volume, the rate of nodules and the level of FT4 were lowest in prepubertal period, followed by pubertal period and postpubertal period ( P<0.05). TT3 and FT3 levels were highest in prepubertal period, followed by pubertal period and postpubertal period ( P<0.001), and there was an opposite trend on the abnormal rate. TSH and TT4 levels were not affected by the stage of puberty ( P>0.05). Multiple linear regression analysis and multivariate logistic regression analysis showed consistent results. There was a negative correlation between puberty development and TT3 and FT3 levels. For each 1 point increase in PDS, TT3 and FT3 levels decreased by 0.067 nmol/L and 0.170 nmol/L in Model 1, respectively, and decreased by 0.065 nmol/L and 0.162 nmol/L in Model 2, respectively. Compared with the prepubertal period, the TT3 and FT3 levels were lower in postpubertal period (Model 1: OR=0.337, 95 %CI: 0.173-0.658; OR=0.283, 95 %CI: 0.144-0.557; Model 2: OR=0.306, 95 %CI: 0.155-0.605; OR=0.263, 95 %CI: 0.132-0.524). Conclusions:The process of puberty is related to the thyroid status in women. The better matured during the puberty, the larger volume the thyroid was, more likely the thyroid nodules appeared, and the levels of TT3 and FT3 was much lower.
9.Serological evaluation of immune effect of inactivated COVID-19 vaccine in adult population in Deqing County, Huzhou City, Zhejiang Province
Chuanwu MAO ; Yingfeng CHEN ; Li ZHANG ; Yuyang XIE ; Xiaolian DONG ; Lufang JIANG ; Qingwu JIANG
Shanghai Journal of Preventive Medicine 2022;34(11):1118-1122
ObjectiveTo investigate the specific anti-SARS-CoV-2 antibody in adults and above after initial vaccination with inactivated COVID-19 vaccine, and determine the influencing factors. MethodsIn this study, residents aged 18 and above who had completed two doses of inactivated COVID-19 vaccine in Deqing County, Huzhou City, Zhejiang Province were included. Information such as gender, age, type of vaccine and vaccination time were collected, and serum specimens were sampled. Anti-SARS-CoV-2 receptor binding domain (RBD) antibody was quantitatively examined by enzyma-linked immunosorbent assay (ELISA) and influencing factors were determined. ResultsThe median concentration of anti-SARS-CoV-2 IgG antibody in the residents vaccinated with an inactivated booster vaccine was higher than that in those vaccinated with only two doses of COVID-19 vaccine or single dose (P<0.05). The median concentration of IgG antibody in males was 9.73 (4.01‒23.70) RU‧mL-1, lower than 17.76 (7.07‒49.23) RU‧mL-1 in females (P<0.05). The median concentration in the residents vaccinated with BBIBP-CorV (Sinopharm) was 6.53 (0.97‒13.69) RU‧mL-1, which was lower than that in those vaccinated with CoronaVac (Sinovac) that was 17.29 (8.54‒43.73) RU‧mL-1 (P<0.05). The median concentration in those with BBIBP-CorV was also lower than 12 (5.45‒40.06) RU‧mL-1 in those with heterologous booster vaccine (P<0.05). The median concentration was 9.73 (3.83‒23.63) RU‧mL-1 in the residents with an interval of more than 6 months from the second dose, which was lower than 14.66 (6.36‒35.98) RU‧mL-1 in those with an interval of 3‒6 months (P<0.05). Moreover, immune effect was better in females (χ²=16.464, P<0.05), 18‒45 years(χ²=7.158, P<0.05), and those vaccinated with CornaVac (χ²=49.637, P<0.05), while decreased in those with an interval of more than 6 months from the second dose (χ²=8.447, P<0.05). ConclusionGender, age, and type of vaccine may affect the effect of immunization. The COVID-19 vaccination shows an acceptable immunogenicity in adults; however, it declines in 6 months after vaccination. It warrants strengthening the booster vaccination to maintain the immune response.
10.Hazards of game addiction to health in adolescents
Xiaolian DONG ; Yizhou JIANG ; Yixuan ZHANG ; Weibo ZHANG ; Na WANG
Shanghai Journal of Preventive Medicine 2022;34(5):504-508
Gaming addiction, as a main manifestation of internet addiction, is characterized by a pattern of persistent or recurrent gaming behaviors. Gaming behaviors are common among adolescents and can result in marked distress or significant impairment in personal, family, social or other important areas of functioning. Recent research on health hazards of gaming addiction is relatively scattered. This article reviews the harm of adolescent game addiction to physical and mental health.