Objective To explore the clinical value of intravenous thrombolysis in the treatment of patients with acute myocardial infarction (AMI) and cardiac arrest after cardiopulmonary resuscitation.Methods 120 patients with AMI and cardiac arrest admitted in our hospital from Mar 2009 to Mar 2013 were divided into thrombolytic group (n=50) and control group (n=70) according to the voluntary principle.The recanalization rate,return time of spontaneous circulation,left ventricular ejection fraction (LVEF) and creatine kinase-MB (CK-MB),complications and hospital mortality rate were compared between two groups.Results The recanalization rate was significantly higher in thrombolytic group than in control group (76％ vs.11.4％,x2 =84.81,P＜ 0.05).Restoration of spontaneous circulation was significantly shorter and LVEF after one week of treatment and CK-MB peak were significantly higher in thrombolytic group than in the control group (t=6.796,4.342,2.923,respectively,P＜0.001 or 0.05).The incidences of heart failure,angina,arrhythmia,and re-infarction were significantly lower in thrombolytic group than in control group (x2 =6.10,20.95,8.52,11.10,respectively,all P＜0.05).There were no significant differences in the incidences of intracranial hemorrhage and upper gastrointestinal bleeding between thrombolytic group and control group (x2 =2.19,3.74,both P＞0.05).Hospital mortality rate was significantly lower in thrombolytic group than in control group (10 ％ vs.25.7 ％,x2 =4.65,P＜0.05).Conclusions Intravenous thrombolysis has a higher recanalization rate,faster recovery time of spontaneous circulation,fewer complications and higher hospital survival rate for the treatment of cardiac arrest in patients with acute myocardial infarction after cardiopulmonary resuscitation.

Food allergy ( FA ) often leads to protracted diarrhea and chronic diarrhea, which influence children′s nutrition and growth seriously and early diagnosis and treatment is particularly important. Its pathogenesis includes IgE mediated,not IgE mediated,and mix. Mainly manifestations include:food protein mediated rectum colitis, food proteins mediated enterocolitis syndrome,food proteins mediated bowel disease,and coeliac disease ( CD) . Diagnosis should be asked for details of the history. Diet avoidance and open food challenge tests help determine the diagnosis. Treatment mainly for suspicious foods to avoid,breastfeeding should be continue,mothers need to avoid food allergies, artificial feeding should be changed to extensively hydrolysed protein formula( eHF) or amino acid-based formula( AAF) feeding. Try not to use of antibiotics,and to give support therapy. Early diagnosis and treatment,correct nutritional gui-dance can prevent serious complications,reduce its incidence.

Objective To investigate the effect of enteral nutrition on the improvement of the nutritional status and prevention of complications in elderly stroke patients with eating difficulties,and provide theoretical guidance for clinical treatment.Methods Eighty-two cases of elderly stroke patients with eating difficulties after stroke were randomly divided into two groups by the time of admission,41 cases in control group were given with parenteral alimentation,and 41 cases in treatment group were given with enteral nutrition.Before treatment and 3 weeks after treatment triceps skinfold (TSF),arm muscle circumference (AMC),serum hemoglobin (Hb),albumin (ALB),serum total protein (TP),high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),triglycerides (TG),total cholesterol (TC) and fasting plasma glucose (FPG) was measured,and the incidence of complications was observed.Results The TSF,AMC,Hb,ALB,TP,HDL-C,LDL-C,TG,TC and FPG after 3 weeks treatment in control group was significantly lower than that before treatment (P ＜ 0.05),but in treatment group compared with that before treatment there was no significant difference (P ＞ 0.05).The TSF,AMC,Hb,ALB,TP,HDL-C,LDL-C,TG,TC and FPG after 3 weeks treatment in treatment group was significantly higher than that in control group (P ＜ 0.05).The incidence of complications in treatment group was signifcanfly lower than that in control group [36.6％ (15/41) vs.78.0％ (32/41)] (P ＜ 0.05).Conclusions Enteral nutrition is conducive to the nutritional status of elderly stroke patients with dysphagia improvement,and can greatly reduce the incidence of complications,and improve survival rate.It is worthy of promotion.

Objective To analyze nursing risk factors in digesting internal medicine nurses,looking for effective prevention measures and observe the nursing effect. Methods Nursing risk factors were analyzed from November 2009 to October 2010,and effective preventive measures were explored and applied from November 2010 to October 2011.The incidence rate of nursing accidents,the degree of satisfaction and approval,and basic nursing quality were compared before and after the implementation of nursing risk preventive measures. Results Nursing accident before and after the implementation was 0.98％ and 0.12％,the degree of satisfaction and approval before and after the implementation was 78％ and 75％,the basic nursing quality score before and after the implementation was (93.87 ±1.26)points,(99.68 ±0.54)points,the results before and after the implementation showed significant difference. Conclusions To adopt effective nursing risk preventive measures can significantly reduce the incidence of nursing risk,improve nursing service quality and satisfaction degree of patients.

The Notch receptors of mammalian include four kinds from Notch1 to Notch4.Notch ligands are divided into two families,Delta and Jagged,including Delta 1,Delta 3,Delta 4,Jaggedl and Jagged2.Notch signaling pathway is a complex network structure which is composed by receptors,ligands and downstream target genes,and it is closely related to cell proliferation,diferentiation and apoptosis.It has carcinoma suppressing or carcinogenic effects in different tissues and cells.This article mainly describes the regulation of Notch signaling pathway and its effect on children with acute leukemia.

It is inevitable that the construction of urban and rural medical security system is the law of economic and social development,but there are still more constraints in this social system engineering.Deep analysis and research were carried out from six aspects in this paper such as the constraints of traditional thought and economy,obstruction of the existing household registration system,constraints of the existing land system,legal obstacles and institutional barriers; and ways to solve the problems were trying to be found in order to methods for the construction of the urban and rural medical security system in our country.

Implementing PBL teaching in the political theory course,making sure the scientific nature of the problem setting are the fundamental guarantees of the right track of political theory education.There are several specific approaches to implement the PBL teaching effectively:leading up to the problem when teacheing in the large class; completing the analysis and research by dividing groups; carrying out class discussions by teams; submitting discussion experiences by each student.Practice has proved that,PBL teaching is better than LBL one.

Objective To explore effective health education methods about diabetes mellitus and increase the health education qulity for patients with diabetes mellitus.Methods Patients with diabetes mellitus(192 cases)were divided into the test group and the control group with 96 cases in each group.The control group received routine health education.Health education pathway inventory was established for patients in the test group.The concrete aim of health education was considered and objective teaching method was used combined with clinical pathway.The health education effect was compared in the two groups.Results The excellent rate of health education knowledge and total satisfactory rate with nursing service in the test group was higher than that of the control group(P＜0.05).The blood slucose control in the test group Wag better than that of the control group(P＜0.05).Conclusion Objective teaching method combined with clinical pathway proved to be an effective health education method for diabetes mellitus.

The result of ultrasonic examination for 24 cases with adrenal tumors proved by pathology was reported.Various acoustic image features are described and the causes of errors and misdingnosis as well as the value and certain noted problems in diagnosing are analysed and discussed.A comparison is made for the data of this group with those by CT,the former showing no inferiority tO thelatter.

AIM: To verify the protection of astragalus polysaecharide (APS) on H2O2 - stressed skin fibro-blasts. METHODS: A model of acute H2O2 stress in primary skin fibroblast was used at concentration of 0.5 mmol/L by 30 rain incubation. Dose responses of APS on cell survival was measured by MTI, cell death was evaluated by DAPI, and effect of APS on mitochondria, mitochondrial membrane potential and lysesome stabilization were measured by confocal microscopy. RESULTS: APS improved cell survival in a dose -dependent manner, starting at 0. 5 mg/L and with a maximum at 1 mg/L. Moreover, APS inhibited mitochondrial membrane potential collapse, protected mitechondrial morphology and stablized lysosomal membrane. CONCLUSION: The results suggest the existence, at the mitochondria-lysosome level, of a new pathway of apoptotic regulation by APS. This might constitute a new therapeutic target where oxidative stress and lysesomal impairment are involved.