Objective To explore the application and implementation of narrow band imaging (NBI) in fiberscope.Methods NBI color filter in the light source gifted the host machine with NBI function,and the application of DBI technique in fiberscope was implemented with a compatible HD camera.Results NBI technique involved in fiberscope decreased the costs in hospital and departments,relieved patient pain and increased the diagnosis rate.Conclusion NBI technique can be applied to electron mirror and fiberscope,and gains advantages in the future.

OBJECTIVE: To study the effects of Tangmaikang granules on blood sugar and sugar tolerance in diabetic mice and on the sugar tolerance of normal rats.METHODS: The diabetic mouse model was induced by alloxan,and the effects of different dosage of Tangmaikang granules on blood sugar and sugar tolerance in experimental diabetic mice and on the sugar tolerance of normal rats were observed.RESULTS: Tangmaikang granules(Medium-dose and high-dose) could downregulate the blood sugar level of experimental diabetic mice and inhibited the glucose-induced increase of the blood sugar level,showing significant differences as compared with the model group(P

Objective To explore the importance of pre hospital emergency care for patients with hypertensive cerebral hemorrhage.Methods A total of 85 patients with hypertensive cerebral hemorrhage transferred by ambulance were considered as the observation group and 51 patients with hypertensive cerebral hemorrhage transferred by family members were considered as the control group.Patients in observation group were given first aid at the scene,transit and hospital,and patients in control group were given first aid after admission in hospital.Effective transit time,complications,and mortality were compared between the two groups.Results Effective transit time was shorter in observation group than in control group [(0.92±0.17) h vs.(1.31±0.39) h,t=8.05,P＜0.001].The complication incidence was lower in observation group than in control group (14.12％ vs.47.06％,x2 =17.77,P＜0.001).The mortality rate was lower in observation group than in control group (15.29 ％ vs.37.25 ％,x2 =8.54,P ＜ 0.01).Conclusions Pre-hospital emergency care could shorten the effective transit time,reduce the complication incidence and improve the survival rate in patients with hypertensive cerebral hemorrhage

Combining technical requirement from main international administration and status quo of China administration, current regulatory requirement on clinical trail of conventional intervertebral fusion devices has been simplified. Cervical, thoracic and lumbar cases can be grouped into the same cohort, and primary endpoints are mainly based on imageology rather than clinical score. This is an attempt to rationally lessen industrial burdensome.
China ; Clinical Trials as Topic ; standards ; Cohort Studies ; Endpoint Determination ; Humans ; Research Design ; standards ; Spinal Fusion ; instrumentation

In recent years, a rapid development has been achieved in the clinical prevention of hepatocellular carcinoma recurrence after liver transplantation, especially in perioperative management, which are supported by the results of evidence-based studies.However, due to the complicated procedures and varied risk factors for liver transplantation, the prevention of postoperative carcinoma recurrence remains a challenge and a focus of research in liver transplantation.This study reviews the perioperative measures for the prevention of hepatocellular carcinoma recurrence after liver transplantation, aiming to shed some light on this aspect for graduates and clinicians of surgery.

Objective To summarize the clinical features of patients suffering from pulmonary embolism (PE) with D-dimer ＜ 0. 5 μg/mL in order to raise the diagnostic accuracy and reduce the mortality rate of PE. MethodsD-dimer-negative patients with suspected PE were admitted from January 2006 through December 2009. A comparison of clinical features including clinical manifestations, vital signs, laboratory and ancillary findings between 16 patients finally diagnosed PE and 41 patients without PE. ResultsCompared with patients without PE, the D-dimer-negative patients with PE usually had past history of venous thromembolism (VTE) or recent surgery. The symptoms of chest tightness, acute dyspnea, tachypnea, lower extremity edema and typical S I QⅢTⅢ changes of ECG were more often occurred in patients with PE than those in patients without PE of control group. ConclusionsD-dimer test is a good screening test for acute PE because its negative predictive value is high, but when the patients have acute dyspnea, lower extremity edema, previous history of VTE or/and recent surgery and ECG SI QⅢ TⅢ changes, even if D -dimer ＜ 0. 5 μg/mL, clinicians also should pay attention to and if necessary, further tests should be considered to confirm the diagnosis of PE.

How to choose an appropriate experimental design type to arrange research factors and their levels is an important issue in experimental research. Choosing an appropriate design type is directly related to the accuracy and reliability of the research result. When confronting a practical issue, how can researchers choose the most appropriate design type to arrange the experiment based on research objective and specified situation? This article mainly introduces the related contents of the single-group design and the paired design through practical examples.

Objective To evaluate the effect of local infiltration anesthesia with different concentrations of ropivacaine on the healing of incision in rats.Methods Seventy-five adult male Sprague-Dawley rats,weighing 220-250 g,were randomly divided into 5 groups (n =15 each):natural healing group (group C),normal saline group (group NS),0.20％ ropivacaine group (group R0.20),0.50％ ropivacaine group (group R0.50) and 0.75％ ropivacaine group (group R075).0.20％,0.05％ and 0.75％ ropivacaine 1.0 ml/kg were injected subcutaneously 10 min before incision in R0.20,R0.50 and R0.75 groups,respectively,while the equal volume of normal saline was given instead in group NS.Five rats in each group were chosen for recording the healing time.Ten rats were taken in each group for recording the length of the incision 72 h after operation.The skin tissues around the incision were removed for determination of fibroblast counts under light microscope,IL-1β content (by ELISA) and the expression of collagen (by immunohistochemisty) and IL-1β mRNA (by RT-PCR).Results Compared with Cgroup,the healing time and length of the incision were significantly shortened,the fibroblast counts and expression of collagen were increased in R0.20 group,the healing time and length of the incision were shortened,the fibroblast counts and expression of collagen were increased,and the expression of IL-1β mRN A and IL-1β content were decreased in R0.50 group,and the healing time and length of the incision were prolonged,the fibroblast counts and expression of collagen were decreased,and the expression of IL-1β mRNA and IL-1β content were decreased in R0.75 group (P ＜ 0.05).Compared with R0.20 group,the healing time and length of the incision were significantly shortened,the fibroblast counts and expression of collagen were increased,and the expression of IL-1β mRNA and IL-1β content were decreased in group R0.50,the healing time and length of the incision were significantly prolonged,the fibroblast counts and expression of collagen were decreased,and the expression of IL-1β mRNA and IL-1β content were decreased in group R0.75 (P ＜ 0.05).Compared with R0.50 group,the healing time and length of the incision were significantly prolonged,the fibroblast counts and expression of collagen were decreased,and the expression of IL-1β mRNA and IL-1β content were decreased in group R0.75 group (P ＜ 0.05).Conclusion Local infiltration anesthesia with 0.20％ and 0.50％ ropivacaine can promote the healing of incision in rats,0.50％ ropivacaine provides better efficacy than 0.20％ ropivacaine,and 0.75 ％ ropivacaine can inhibit the healing process.

Hospital culture plays a more and more important role,among various factors that influence employee satisfaction.Study on hospital culture is gradually growing out of a pure conceptual research and emerging into an area of correlation analysis. Our studies on the hospital culture developments and employee satisfaction in a tertiary hospital,analyzed the correlations between hospital culture and employee satisfaction and its impact,with recommendations for reform strategies.

Objective To investigate the relationship of the location of nerve compression and different type of trigeminal neuralgia.Methods Twenty-one patients with typical trigeminal neuralgia and 16 patients with atypical trigeminal neuralgia were treated by micro-vascular decompression.The position of the responsible vessels was probed during operation.Results Compared with atypical trigeminal neuralgia group, the compression rate of trigeminal root entry/exit zone (REZ) in typical trigeminal neuralgia group was significantly higher(P<0.01).The compression rate of trigeminal REZ which oppressed by artery in typical trigeminal neuralgia group was significantly higher than that in atypical trigeminal neuralgia group ( P<0.01 ) .Conclusions The responsible vessels in typical trigeminal neuralgia patients is mostly located in the trigeminal REZ, and the responsible vessels is mostly not located in other location in the trigeminal REZ.The responsible vessels oppress REZ is closely related to types of trigeminal neuralgia.