With postgraduates coming form different parts of the country,with complicated community structure,and dispersive professional study,the ideological political education of the postgraduates are difficult to be developed.Academic activities,which can infiltrate the ideological political education,can construct an equitable and effective communicated platform,improve the comprehensive quality of the postgraduates.Accordingly,academic activities can optimize the soft environment of the ideological political education.

OBJECTIVE To report one case of primary Cryptococcus neoformans pneumonia misdiagnosed to sarcoidosis with its clinical presentations,pathology and imaging manifestation.METHODS Sarcoidosis was obtained by CT and pathologic examination.RESULTS The patient showed fever,headache and abnormal shadows in the lung field after six months.Cerebrospinal fluid examination was defined as C.neoformans.Afer review of his pathology it was diagnosed primary C.neoformans pneumonia.CONCLUSIONS C.neoformans pneumonia always shows no symptoms;only can be showed by CT as multiple nodules or large patches,and always misdiagnosed.

Objective The article introduced the application of the project schedule management in the con-struction of large-scale general hospital information system project and the important role that it played in the con -struction.Methods By the examples of the informationization construction of a new large -scale general hospital , this paper discussed the schedule management and control method in order to illustrate the fact role it played , inclu-ding the hospital information project activity definition , activity sequencing , resource estimation , time estimation, schedule planning and schedule control of the whole process .Results Through the effect seen above , we carried out the effective control of the project schedule and ensured the project goals on schedule .Conclusion Project schedule management is an important guarantee in informationization construction of large -scale general hospital , while impro-ving the management of large programs .

T-lymphoblastic lymphoma (T-LBL) is a rare form of non-Hodgkin lymphoma (NHL),which is biologically similar to T-acute lymphoblastic leukemia(ALL),and occurs most frequently in childhood and adolescence.T-LBL progresses fast.The treatment of LBL with conventional chemotherapy regimens for NHL has shown relatively low rates of complete remission and of disease-free survival.Now,it is reasonable to treat patients with LBL with the current ALL-type protocols,and hematopoietic stem cell transplantation may yield a more favorable overall survival (OS) in T-LBL patients,especial in relapsed or refractory LBL patients.

There were 417 scientific articles on hematopoietic stem cell transplantation in the 54th annual meeting of American Society of Hematology (ASH),including 46 articles on lymphoma.This article reviews latest research on non-myeloablative allogeneic hematopoietic stem cell transplantation for the treatment non-Hodgkin' s lymphoma presented in the meeting.

Objective To investigate the inhibitory effect of Arg-Gly-Asp-Ser (RGDS) on proliferation and collagen synthesis stimulated by fibronectin (FN) and the influence on the expression of focal adhesion kinase of hepatic stellate cell (HSC), in order to provide a theoretical ground for its use in prevention and treatment of hepatic fibrosis in clinic. Methods The adhesion rates were determined by toluidine blue colorimetric assay. The effects of RGDS on the proliferation and collagen synthesis of HSC were assessed by ~3H-TdR and 3H-proline incorporation assays, respectively. The FAK mRNA of HSCs was determined by RT-PCR. Results RGDS was found to inhibit the rates of adhesion, while RGES has no such ability; ②The proliferation and collagen synthesis of HSC were inhibited by RGDS in dose and time-dependent manners; ③The expression of FAK in the (25, 50, 100mg/L) RGDS groups was significantly lower than that in the control group at mRNA level. Conclusions RGDS can inhibit proliferation and collagen synthesis of HSC, and these effects correlate with its anti-adhesion ability. Meanwhile the expression of FAK is also down-regulated significantly. As a signaling molecule, FAK may be involved in the effect of RGDS. This may be one of the underlying mechanisms of anti-fibrosis effect of RGDS.

Objective To investigate the current work situation of senior clinical nurses to provide some advices for the nursing management .Methods The self-made questionnaires were adopted to investigate the work situation of 60 senior nurses for conduc-ting the descriptive analysis .Results The senior nurses′ satisfaction degrees to the professional self -identity ,the chief nurse′s scheduling ,the current work environment ,the approval by hospital and the emphasis degree by the department were not high .They thought that the suitable position for them was the office nurse and the second was the responsibility group leader .Whereas ,the un-dertaking key post at present was the responsibility group leader and the second was the office nurse .Conclusion Due to the partic-ularity of nursing work and the physiological and psychological change ,the senior nurses are unsuitable to the busy front -line work ;the senior clinical nurses have the rich clinical experience ,the stronger communicational and organizational coordination abili-ty ,and are more suitable for the posts of the office nurse and health education nurse ,and second is the post of responsibility group leader .

The rat anti-HRP McAbs were prepared with rat-rat hybridoma and the rat McPAP complex was made by conjugating this McAb with HRP. The results of the present work indicated that the rat MePAP can be used for detection of antibodyantigen reaction by immunohistochemical techniques and ELISA. In both assay it gave strong staining reaction for positive antigen and with background staining appeared very pale. The sensitivity of rat McPAP and HRP labelling rabbit anti-rat IgG has been compared.

In order to investigate the effect of vitamin A (VA) on the secretion of IFN-gamma and IL-4 in Mycoplasma Pneumoniae (MP)-induced A549 cells, A549 cells were co-cultured with MP for different time lengths and then the levels of IFN-gamma and IL-4 in the cell culture supernatants were detected before and after treatment with different concentrations of VA by using the enzyme-linked immunosorbent assay (ELISA). The results showed that the level of IFN-gamma and IL-4 in the supernatants of MP-induced A549 cells was much higher than that in non-induced cells (P<0.01). After application of VA, IL-4 level was not increased until the concentration of VA was up to 0.5x10(-5) mol/L (P<0.01). However, with concentration of VA increased up to 1x10(-4) mol/L, IL-4 was significantly suppressed (P<0.01). It was concluded that MP could induce the secretion of IFN-gamma and IL-4 in A549 cells. VA could inhibit the secretion of IFN-gamma and increase the IL-4 level in MP-induced A549 cells. However, high concentration of VA had an inhibitory effect on the secretion of IL-4 as well as on the IFN-gamma. These data provided a theoretical basis for the application of VA in MP pneumonia in the clinical practice.
Cell Line, Tumor ; Coculture Techniques ; Culture Techniques ; Interferon-gamma/*secretion ; Interleukin-4/*secretion ; Lung Neoplasms/pathology ; Mycoplasma pneumoniae/growth & development ; Mycoplasma pneumoniae/*physiology ; Vitamin A/*pharmacology

Objective To investigate the efficacy and safety of using adsorption method combined with warm saline in heparin- free dialysis for patients with high risk bleeding tendency in order to reduce blood ag-glutination in the dialyzer and pipeline. Methods 60 patients with high risk bleeding tendency who were to undergo long- term hemodialysis (HD) were divided into the experimental group and the control group with 30 eases in each group,they both adopted heparin- free dialysis.The control group used saline washing of room temperature, while the experimental group adopted adsorption method combined with warm saline during washing. The completion of dialysis as well as the agglutination in the dialyzer and pipeline were ob-served. Results Number of patients who completed the dialysis were more, the completion rate of dialysis was higher and agglutination of dialyzer and pipeline decreased in the experimental group than those in the control group. Conclusions Agglutination of dialyzer and pipeline can be reduced and the aim of safe and effective heparin- free dialysis can be reached when using adsorption method combined with warm saline.