OBJECTIVE: To discuss the application of endotracheal intubation in the rescue of children with severe trachea and bronchial foreign body. By observing the patient's clinical pathological characteristics, the diagnosis and treatment experience were summarized. METHOD: A retrospective analysis of 10 children with severe tracheal and bronchial foreign bodies were performed. They were given emergency intubation and cardiopulmonary resuscitation to relieve respiratory and circulatory failure after reaching hospital. After the restoration of spontaneous respiration, oxygen saturation increased by more than 90 percent and vital signs stable, the foreigh body was removed with bronchoscopy. The role of endotracheal intubation before and after the treatment of tracheal and bronchial foreign bodies in children was observed. RESULT: Ten cases of children were rescued successfully. No one died and the complications such as cerebral palsy, pneumothorax and pneumomediastinum didn't happened. CONCLUSION For the children with severe tracheal and bronchial foreign body, endotracheal intubation can establish effective ventilation in a shorter period of time. The earlier endotracheal intubation, the shorter time required and the higher success rate. Endotracheal intubation can increase the survival rate of children with cardiopulmonary resuscitation, and can reduce disability.
Bronchi ; physiopathology ; Bronchoscopy ; Child ; Foreign Bodies ; therapy ; Humans ; Intubation, Intratracheal ; Retrospective Studies ; Trachea ; physiopathology

Objective In order to explore pathogenesis about inflammation injury of the hematoma peripheral zone after cerebral hemorrhage. Methods 48 adult male wistar rats are randomly divided into intracerebral hemorrhage (ICH) groupand control group. After 3 h, 24 h,72 h and 7 d of ICH, intercellular adhesion molecule-1 (ICAM-1)was detected by immunohistochemical SABC staining in rats brain slice. Positive cells expression of the ICAM-1 were measured by color image analysis system。Brain edema were assayed by dry-wet weight method. Results The expression of ICAM-1 increased at 3 h ( P 0.05) compared to contral group. Conclusions The overexpression of ICAM-1 may play important role in the perihematoma edema formation and ischemic injury.

OBJECTIVE:To evaluate the clinical efficacy of Xuebijing injection in treating acute paraquat poisoning.METHODS:35 patients with acute severe parquat poisoning who were admitted into ICU of our hospital from Jan.2002 to Apr.2008 were enrolled in our study:15 cases were assigned to control group,20(treatment group)received Xuebijing 100 mL bid for 7～10 d in addition to the therapy as in control group.RESULTS:Liver enzyme and creatinine levels in both group were reduced,with the level in the treatment group significantly lower than in control group(P

Objective To investigate the impacting factors on the professional identity of railway young workers and the relationship of the professional identity and subjective well-being.Methods The sample consisting of 5 762 young workers was selected from railway enterprises by stratified and random sampling according to the proportion.Occupational professional identity Scale and Index of Well-being,Index of General Affect Scale were used.The affect of the variable,such as sex,age,working years,educational background and income on professional identity were studied.Moreover,the relationship between professional identity and subjective well-being was reported.Results (1) Professional identity ascended witb the increase of ages,and there was significance between three groups(F=6.667,P＜0.05).(2)Professional identity ascended with the increase of length of service (F=5.147,P＜0.01),but it dropped at the point of 9-12 years.(3) The professional identity of workers with bachelor degree was higher than that with junior college education background.and there was significance between three groups (F=3.538,P＜0.05).(4)The workers who had more than 3 500 RMB monthly salary was regarded on the top in professional identity,while those whose monthly salary were under 2 500 RMB was in the lowest level (F=42.275,P＜0.01).(5)The result of linear regression indicated that the degree of professional identity can forecast the degree of subjective well-being(R =0.534,P＜0.01).Conclusion The professional identity of railway young works was affected by their ages,the length of service,the educational degree and salary,The professional identity can forecast subjective well-being.

Objective To explore the relationship among psychological capital,job burnout and job engagement of knowledge workers.Methods According to convenience sampling principle,727 information enterprise knowledge workers in Beijing were tested by Psychological Capital Scale,Maslach Burnout Inventory-General Survey (MBI-GS),Utrecht Work Engagement Scale(UWES),and the impact of psychological capital on job burnout and job engagement with correlation analysis and multivariate stepwise regression analysis were explored.Results The level of each dimension of the knowledge workers psychological capital (self-efficacy (4.72 ± 0.72),hope (4.62 ± 0.77),hardness (4.68 ± 0.72),optimism (4.36 ± 0.55)) were above average.The psychological capital total score and all dimensions were negatively correlated with job burnout,and positively correlated with job engagement.Stepwise multiple regression analysis showed that,after controlling three demographic statistics variables of gender,age,marital status,psychological capital could predict job burnout negatively,and predict job engagement positively; self-efficacy,hardness and optimism could significantly predict the three dimeusions of job burnout,hope could predict reduced personal accomplishment negatively;and self-efficacy could positively predict vigor,dedication and absorption,hardness could positively predict dedication and vigor.Conclusion Psychological capital can reduce the level of job burnout of knowledge workers,and improve their level of job engagement.

It is to investigate the effect of two kinds of Houttuynia Cordata Injection on preventing and treating H1N1 influenza virus infection in mice. Pneumonia model was set up by intranasal infection of the normal and immunocompromised mice with influenza virus FM1 and PR8. The two injections were administered before and after the administration of virus, separately, and the lung index was observed. The results showed that the two preparations have obvious therapeutic effect on normal mice infected with influenza virus FM1 and PR8. And to FM1, the new injection's effect is better at small dosage. The results also showed that the two preparations have obvious prophylactic effect on immunodepressed mice infected with influenza virus FM1 and PR8. And to PR8, the old injection's effect is better at small dosage. Houttuynia Cordata Injection can improve the mice pneumonia caused by influenza virus H1N1 and decrease the lung index markedly. It has a remarkable preventive and therapeutic effect on H1N1 influenza virus in mice.

OBJECTIVE To investigate the distribution of pathogenic bacteria and the status of drug resistance in intensive care unit(ICU) of Anhui Provinceical Hospital,to provide reference for rational use of the antibiotics in clinical practice and effective control of hospital infection.METHODS From Jan 2007 to Dec 2008,a total of 873 clinical isolates were collected from different samples of infective patients in ICU,drug sensitivity test was conducted based on disk diffusion testing(K-B),to analyze the drug resistance of the pathogenic bacteria.RESULTS The highest isolating rate came from the sample of respiratory tract,which was 68.96%.Among 873 clinical isolates,Gram-negative bacilli and Gram-positive cocci accounted for 65.95% and 19.22%,respectively.Gram positive cocci rised obviously in 2008 compared to 2007.The rate of bacterial drug resistance was relatively high,meticillin-resistant Staphylococcus aureus(MRSA) detection rate was 56.58%;The detection rates Escherichia coli and Klebsiella ESBLs were 75.00% and 57.41%.CONCLUSIONS There is a higher rate of infection for ICU patients,and the condition of drug resistance is serious.To strengthen the pathogen distribution and drug resistance monitoring is of great guiding significance for rational clinical use of drug,reducing multi-drug resistance and nosocomial infection control.

Objective To explore the clinical efficacy and safety of atorvastatin in the treatment of patients with septic shock.Methods 67 patients with septic shock were randomly divided into the treatment group (34 cases) and control group(33 cases).The control group was treated with conventional therapy ,and the observation group was administered with atorvastatin based on the control group .Before and after treatment ,the inflammatory index ,cytokines levels,the number of MODS cases,the number of deaths at 28th day,and the incidence of adverse reactions were com-pared between the two groups .Results The heart rate ,respiratory rate ,white blood cell count of the treatment group were significantly better than the control group ,the cytokines levels were significantly lower than the control group ,the differences were statistically significant (t=4.181,3.622,4.879,all P<0.05).The incidence rate of MODS of treat-ment group was significantly lower than that of the control group (χ2 =7.153,P<0.05).The average hospital stay of the treatment group was (9.3 ±3.1)d,which was significantly less than (12.4 ±3.3)d of the control group(t=3.964,P<0.05).The incidence rate of adverse reaction in the treatment group was significantly lower than that of the control group(χ2 =4.566,P<0.05).The 28 d mortality rate of the two groups had no significant difference (χ2 =3.345,P>0.05).Conclusion Atorvastatin can effectively reduce the degree of inflammatory reaction in patients with septic shock ,decrease the incidence of MODS , and has potential benefits on the prognosis of patients , but still need to be further confirmed by clinical research .