Eye and nervous system are anatomically and physiologically very close.About 40% of the nerve fibers in brain are correlated with visual function.Seven of twelve cranial nerves are straightly correlated with visual afferent or eye movement.Neurological diseases can affect eye in many different ways.Furthermore,systemic disorders can cause secondary neurological lesions or even primary neurological disorders,which sequentially show ocular symptoms and signs.Better understanding of the close relationship between eye and brain,together with intimate cooperation between ophthalmologists,neurologists,neurosurgeons and other specialties,are the key point to improve our neuro-ophthalmology service in China.

Objective To know the dynamic dose of individual external exposure for radiological workers in Qinghai province from 2001 to 2005. Methods Individual exposed dose for 2 733 radiological workers were measured with thermoluminescent method. Results Individual average effective dose was less than 0.53 mSv/a, 97.84% of radiological workers dose was less than 5 mSv/a. Conclusion The individual external exposure level for radiological workers is less than 5 mSv/a in Qinghai Province and it does not exceed the national standard limit.

Apoptosis plays a crucial role in various physiology and pathologic processes of organisms.The non-invasive imaging of apoptosis may have potentially important diagnostic and prognostic predictive values on apoptosis-associated diseases, such as neurodegenerative diseases and neoplasms.Molecular imaging of nuclear medicine provides a useful tool to investigate these features in vivo by using suitable radiopharmaceuticals.This review summarizes the recent advances in imaging agents targeting the apoptosis process.

Alpha-fetoprotein is an important molecular marker for clinical diagnosis, evaluation of curative effect and prognosis of cancer for long time, especially for hepatocellular carcinoma. But for physiological function of alpha-fetoprotein, we know less than its clinical significance. So here this article presents a review about physiological function of alpha-fetoprotein and its application in molecular therapy of hepatocellular carcinoma.

Neovascularization is one of the crucial challenges in tissue-engineered grafts.In order to find sdution to the problem,endothelial cells and animals were exposed to electromagnetic fields to examine the formation of new vascular.This review gives an overview of the effects of electromagnetic fields on the neovascularization of tissue-engineered grafts.

Objective To study the effect of transmembrane tumor necrosis factor-alpha (TM-TNF-αt) on human cervical carcinoma HeLa cells,and explore the correlations with silencer of death domain (SODD).Methods The expression of proliferating cell nuclear antigen (PCNA) was detected by immunocytochemistry.The expression of SODD in human cervical carcinoma HeLa cells undisposed and after disposed with TM-TNF-α was detected by reverse transcription-polymerase chain reaction,and the influence of TM-TNF-α on human cervical carcinoma HeLa cells was analyzed.Results The positive rate of PCNA in undisposed human cervical carcinoma HeLa cells was 80.3％ (155/193),in human cervical carcinoma HeLa cells disposed with TM-TNF-α was 46.7％ (85/182),there was statistical difference (P ＜ 0.05).The cycle index of polymerase chain reaction in human cervical carcinoma HeLa cells was 28 times,the amplification product was disposed by 2％ agarose gel electrophoresis,the gray scale disposed by TM-TNF-α and undisposed human cervical carcinoma HeLa cells were 1.377 ± 0.170 and 0.815 ± 0.040,there was statistical difference (P ＜ 0.05).Conclusion TM-TNF-α has obvious cytotoxic effect on human cervical carcinoma HeLa cells in vitro which may due to its up-regulating the expression of SODD.

It has been confirmed that hepatocellular carcinoma belongs to gene related disease.Biological characteristic of hepatocyte can be infected by abnormal expression of related genes,resulting in normal cell transformed to carcinoma cell,therefore,we should do further research to find new methods for diagnosis and treatment of HCC.As a new technique for gene knockdown,RNAi has been applied more in the fields of gene function and gene therapy.This paper is a review about recent advance in HCC gene therapy with RNAi.

High -resolution non -standard medical video roentgenoscoped by X -ray can't make use of universal video interfaces such as VGA, S - Video. Based on non - standard video feature transition algorithm library, high - speed field integration technology for FPGA digital system and VHDL hardware description language, this paper develops a real-time transition system for high-resolution non-standard medical video roentgenoscoped by X-ray.

Objective To investigate the effect of TGF? 1 on expression of MHCⅠ type antigen in human pulmonary squamous cell carcinoma.Methods Expressions of ? 2 M in primary culture cells with rhINF? and rhTGF? 1+rhINF? from human pulmonary squamous cell carcinoma were detected by FCM(Flow Cytometry Method), respectively. Results Expression of ? 2 M in all tumor cell groups was induced significantly by rhINF? ( P 0.05) Conclusion Expression of INF? induced MHCⅠ type antigen in human pulmonary squamous cell carcinoma can be inhibited by TGF? 1.

Objective To investigate the expression of TGF ? 1 in human pulmonary squamous cell carcinoma Methods TGF ? 1 in serum free conditioned medium of different differentiated degree primary cells in culture from human pulmonary squamous cell carcinoma were detected by ELISA Results TGF ? 1 in serum free conditioned medium from all tumor cell groups is significantly higher than from normal bronchial epithelial cell groups ( P 0 05) Conclusion Inhibition effect by TGF ? 1 on cell growth of human pulmonary squamous cell carcinoma is weakened