1.Update of the protective effect of PPAR-? ligand in myocardial ischemia-reperfusion injury
Journal of Medical Postgraduates 2003;0(04):-
With the development of coronary artery recanalization technology,more and more attention are paid to myocardial ischemia-reperfusion injury.PPAR-? is distributed in rat myocardium.Besides insulin sensitizing effect,the ligands of PPAR-? can also exert its protective effects by inhibiting cell inflammatory response and apoptosis.In this review,the author summarized the research advances of the protective effects of the ligands PPAR-? on myocardial ischemia-reperfusion injury.
2.Effect of anesthesia methods on perioperative body temperature in patients undergoing operation for esophagus cancer
Xiaojun HUA ; Faping WU ; Huaying WU
The Journal of Clinical Anesthesiology 2010;26(1):11-13
Objective To investigate the effect of different anesthesia methods on perioperative body temperature. Methods Eighty patients undergoing esophagus cancer resection were randomized into two groups of combined general and epidural anesthesia(GEA, group A,42 cases) and general anesthesia(GA, group B, 38 cases). Epipharynx and peripheral temperatures were recorded at the same time every 30 minutes for 3 hours after induction. Epipharynx temperature was recorded than after when circulating water mattresses and fluid warming were used to rewarming. The incidence of postoperative shivering was recorded. Results The peripheral temperature was gradually decreased after induction in both groups. The core temperature was decreased quickly within the first 1 hour in both groups, which was reduced slowly within the next two hours with a greater magnitude of temperature reduction in group A than that in group B(P<0.05). The incidence of shivering was higher in group A than that in group B during warming up. Conclusion The patients undergoing long procedures such as esophagus cancer recection under GEA is at more risk for hypothermia than those under GA.
3.The use of home-made blenderized diet in nutritional support in old comatose patients
Limei HUA ; Xiaojun LIU ; Wei GAO
Parenteral & Enteral Nutrition 1997;0(02):-
Objective: To observe the effect of home-made blenderized diet on nutritional support in old comatose patients.Methods: Sixty-three old comatose patients were fed with home-made blenderized diet by nosal gastric feeding.Triceps skinfolds were measured every month.The serum levels of albumin,pre-albumin,total number of lymph cells and hemoglobin were analysed every month.Results: No side effects of abdominal pain,dearrhea,nausea and vomiting were observed in the fed patients.The states of nutrition(such as triceps skinfolds,albumin,pre-albumin,total number of lymph cells and hemoglobin) were improved significantly after home-made blenderized diet.Conclusion: The home-made blenderized diet can support the old comatose patients effectively.
4.An ELISA for detection of anti-dsDNA by using plasmid DNA as antigen
Hua XIONG ; Xiaojun LI ; Ming QI
Chinese Journal of Laboratory Medicine 2000;0(06):-
Objective To develop an ELISA for detection of anti-dsDNA antibody by using plasmid DNA as antigen.Methods DNA in plasmid pBV220 for prokaryotic expression vector was purified by base-cleavage. The microtiterplates were pretreated by poly-L-lysine and coated by the plasmid DNA in a dilution of 1∶50 as antigen. An ELISA method for detection of serum anti-dsDNA antibodies was developed with HRP-SPA as enzyme-labeled marker.The IIF using crithidia lucilia as substrate was performed simultaneously for comparison. The serum samples from 64 patients with SLE, 8 with MCTD and 17 with RA were detected. Results The concentration of DNA was 1 54 g/L by UV spectrophotometer at wavelength of 260 nm. The positive percentage of ELISA for anti-dsDNA was higher than that of IIF. By comparison with IIF the positive percentages in SLE, MCTD and RA groups were 23 4% vs 17 2%, 12 5% vs 12 5% and 11 8% vs 5 9%, respectively, and the coincident rates between the 2 methods were 93 8%, 100% and 94 1% respectively. The sensitivity and specificity of the developed ELISA for detection of anti-dsDNA were 100% and 93 4% when IIF was as gold standard.Conclusion The ELISA by using plasmid DNA as antigen to detect anti-dsDNA has fine precision, sensitivity and specificity. Its positive rate is higher than that of IIF thus it will contribute to monitor the activities for SLE patients′ condition.
5.Constructing a tele-consultation platform of medical images based on internet communication
Hua WANG ; Yanwu ZHANG ; Xiaojun DING
Chinese Medical Equipment Journal 2003;0(S1):-
Traditional tele-consultation platform adopts point-point communication.With the development of internet communication and dynamic service page technology,the data transmission of medical images through internet becomes possible.This paper discusses the system structure of remote medical images consultation platform based on internet communication and analyzes the data management and communication mode adopting international ACR-INDEX medical image code.
6.Development of a network management platform for medical equipment maintenance
Yanwu ZHANG ; Xiaojun DING ; Hua WANG
Chinese Medical Equipment Journal 2004;0(08):-
XML dynamic swapper of network data applied, a network management platform for medial equipment maintenance is developed, which is based on hospital LAN communication. J2EE-based multiplayer B/S structure is adopted. With the platform, routine management, malfunction declaration, maintenance service and data totaling can be carried out effectively.
7.Network transmission technology and application of medical video
Yanwu ZHANG ; Xiaojun DING ; Hua WANG
Chinese Medical Equipment Journal 2004;0(07):-
With the review of medical video network transmission technology,this paper mainly analyzes the characteristics of medical video transmission,the distinctiveness of network transmission environment in hospitals and the clinical request coming from the doctor's working in the operating room.A medical video communication technology is proposed that can really meet the clinical request.
8.Algorithm of non-standard video transformation based on FPGA
Lihua ZHENG ; Xiaojun DING ; Hua WANG ; Aimin YU
Chinese Medical Equipment Journal 2004;0(09):-
Objective To study a kind of video transformation algorithm based on FPGA in view of the present situation that the video output of X-ray equipment can not be connected to common video adapter.Methods Through the control of non-standard video signal AD sampling data read-write succession in FIFO,800 digital sampling data was output(output resolution:800?600,refresh rate:60Hz)in the period of every line of effective signal.The output module combined these data with line and field synchronized signal and transform them into standard VGA signal.Results Non-standard medical video signal could be transformed into standard medical video signal by using VHDL in normal FPGA.Conclusion The speed of this algorithm is high,and the transformation effect is clear and smooth.
10.Evaluate the value of anti-CCP antibody and RF in diagnosis of rheumatoid arthritis
Jiwen ZHU ; Xiaojun ZHANG ; Hua ZHU ; Baoping DAI ; Tao WANG
International Journal of Laboratory Medicine 2015;(18):2681-2682,2685
Objective To evaluate the effectiveness of using anti‐cyclic citrullinated peptide (anti‐CCP) antibody or rheumatoid factor(RF) as the single laboratory parameter for rheumatoid arthritis(RA) diagnosis ,versus to using the two parameters in com‐bination .Methods A total of 56 cases of patients with RA were enrolled into RA group ,other 34 cases of patients with out RA were enrolled into non‐RA group .Levels of anti‐CCP antibody and RF were detected by using electro‐chemiluminescence immunoas‐say(ECLIA)and compared between the two groups .And the diagnostic efficacy of single and combined detection of anti‐CCP anti‐body and RF were evaluated .Results The levels of anti‐CCP antibody and RF in the RA group were higher than those in the non‐RA group ,had statistically significant differences(P<0 .05) .In diagnosis of RA ,the areas under receiver operating characteristic (ROC)curve of anti‐CCP antibody and RF were 0 .925 and 0 .822 respectively .The sensitivity and specificity of anti‐CCP antibody were both higher than those of RF .Compared with single detection of anti‐CCP antibody ,there was no significant increase of sensi‐tivity in using anti‐CCP antibody/RF ,whereas the specificity dropped significantly .Combined detection of anti‐CCP antibody and RF ,compared with single detection of anti‐CCP antibody ,had significantly lower sensitivity ,but no significant changes were found in specificity .Conclusion Single detection of anti‐CCP antibody is more effective than RF for diagnosing RA ,while combined detec‐tion of anti‐CCP antibody and RF could not significantly improve the specificity and sensitivity .It is suggested to only use anti‐CCP antibody for diagnosis of RA .