1.Clinical Application of Multi-Planar Reconstruction with 64-slice Spiral CT on Protrusion of Lumbar Disc
Xiaojing YANG ; Xuejiang QIAN ; Lei CUI
Chinese Medical Equipment Journal 2003;0(10):-
Objective To investigate the value of multi planar reconstruction (MPR) with 64-slice spiral CT for diseases of lumbar disc, vertebra and accessory etc. Methods 50 cases of MPR were compared with 64-slice spiral CT on protrusion of lumbar disc at radom. Results MPR with 64-slice spiral CT showed not only the protrusion of lumbar disc but also the diseases of the vertebra,the accessory, and the adjacent tissue. Conclusion MPR with 64-slice spiral CT has a good value in diagnosis of disease of lumbar disc, vertebra, accessory and the adjacent tissue.
2.Rapid Determination of 17 Chemicals Illegally Added into Anti-rheumatic TCM Patches by UPLC-MS/MS
Qiang LI ; Lei YUE ; Xiaojing LI
China Pharmacy 2017;28(12):1692-1696
OBJECTIVE:To establish a rapid determination method for 9 kinds of glucocorticoid and 8 kinds of non-steroidal anti-inflammatory drugs illegally added into anti-rheumatic TCM patches. METHODS:UPLC-MS/MS method was adopted. The samples were separated on Acquity UPLC? BEN C18 column with methanol-water(90:10,V/V)as mobile phase at flow rate 0.4 mL/min. The column temperature was set at 30℃,and sample size was 1μL. The ionization mode was electrospray ion source(ESI):spray needle voltage of 5500 V,ion source spray GS1,GS2 pressure of 50,50 psi,ion source temperature of 500 ℃,scanning range of m/z 50-500. The multiple reaction monitoring(MRM)combined with information-dependent acquisition (IDA) and en-hanced product ion scanning(EPI)was used to rapid qualitative analysis. RESULTS:The detection limits for 17 kinds of chemical components were not more than 0.400 μg/mL. RSDs for precision,repeatability,stability tests were not more than 4.93%,7.69%, 9.57%,respectively. Diclofenac sodium was detected in the sample. CONCLUSIONS:The method is selective and sensitive. It is suitable for qualitative analysis of chemicals illegally added into anti-rheumatism TCM patches.
3.Mesenchymal chondrosarcoma of the orbit:a case report
Lei SUN ; Ling QIU ; Lei YU ; Yan MA ; Xiaojing JIA
Practical Oncology Journal 2014;(4):342-343
Mesenchymal chondrosarcoma originated in the primitive mesenchymal tissue .It usually devel-ops in the short bones such as hand ,foot and body bone ,while extremeIy rare in the orbit .We report a case of mesenchymal chondrosarcoma of the orbit which is confirmed by pathology .
4.Influence of early rehabilitation therapy on prognosis and quality of life in patients with acute myocar-dial infarction
Lifen SONG ; Lin PI ; Xiaojing ZHAO ; Jiangqiao HU ; Lei GAO
Chinese Journal of cardiovascular Rehabilitation Medicine 2017;26(1):5-7
Objective:To explore effect of early rehabilitation therapy on improving prognosis and quality of life (QOL) in patients with acute myocardial infarction (AMI) .Methods :A total of 120 AMI patients treated in our hospital were selected .According to random number table ,they were randomly and equally divided into routine treatment group (n=60 ,received routine treatment) and rehabilitation group (n=60 ,received routine treatment combined rehabilitation therapy ) .Clinical symptoms ,myocardial enzymes ,cardiac function indexes ,complications , QOL ,length of hospital stay and hospitalization cost were statistically analyzed and compared between two groups . Results :Compared with routine treatment group after treatment ,there were significant reductions in incidence rates of dizziness ,low back pain ,leg weakness ,constipation ,palpitations (P<0.05~ <0.01) ,abdominal distension and complications (36.7% vs .5.0% );significant rise in Barthel index [ (61.9 ± 8.7) scores vs .(86.4 ± 6.9) scores] , significant reductions in length of hospital stay [(13.8 ± 3.2) d vs .(5.9 ± 2.6) d] and hospitalization cost [(13600 ± 1450) RMB vs .(8600 ± 1240) RMB] in rehabilitation group ,P<0.05~ <0.01 .Conclusion:Early rehabilitation therapy can significantly improve prognosis and quality of life ,shorten length of hospital stay , lower hospitalization cost in patients with acute myocardial infarction ,which is worth clinical extending .
5.Integrated account audits management of medical insurance payment
Difei WANG ; Xiaojing WANG ; Boya ZHAO ; Xu GUO ; Lei JI
Chinese Journal of Hospital Administration 2013;29(8):606-609
Using the enterprise resource planning(ERP)management mode,the paper analyzed the present medical insurance payment audit accounts at public hospitals,and probed into the establishment of an information management platform for medical insurance payment audit accounts in the ERP environment.The purpose is to perfect the management of medical insurance payment audit accounts,increase the efficiency of hospital's working capital,strengthen the quality and efficiency of hospital management.
6.Study on Immunocompetence of Active Constituent of Radix Ranunculi Ternati
Zhenling ZHANG ; Xiaojing WU ; Lei WANG ; Huixia ZHANG ;
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(02):-
Objective: To determine the effects of active constituent of Radix Ranunculi Ternati on immune function of experimental animal.Methods: Immune suppression mouse models were made by cyclophosphamide method.After intragastric administration,the effects of polysaccharide and saponin of Radix Ranunculi Ternati on phagocytosis of peritoneal macrophage,formation of hemolysin and T-lymphocyte population of peripheral blood were observed and compared.Results: These two active constituent can highten the percent and the index of phagocytosis,enhancement the formation of the hemolysin obviously and increase the number of T-lymphocytes in peripheral blood.Conclusion: The active part of Radix Ranunculi Ternati can stimulate the immunologic function of immune suppression mouse models.
7.Chemical constituents from the leaves of Ilex pernyi
Guangbo XIE ; Feng NIU ; Xiaojing WANG ; Liandi LEI ; Pengfei TU
Acta Pharmaceutica Sinica 2008;43(1):60-62
A new compound and five known compounds were isolated from the ethanolic extract of the leaves of Ilex pernyi Franch. Their structures were established on the basis of spectral analysis and identified as trans-isoeugenyl-α-L-arabinopynosyl(1→6)-β-D-glucopyranoside (1), kaempferol-3-O-sambubioside (2), quercetin-3-O-sambubioside (3), isoquercitrin (4), (+)-syringaresinol-O-β-D-glucopyranoside (5), amarantholidoside IV (6). Among them, compound 1 is a new phenolic glycoside, named as ilexperphenoside A, and compounds 2-6 were isolated from this plant for the first time.
8.Clinical effect of elbow anterolateral approach with internal fixation in the treatment of capitellum fractures
Zheer PAN ; Lichuang WU ; Xiaojing HUANG ; Lei CHEN
Chinese Journal of Geriatrics 2013;32(11):1180-1182
Objective To investigate the clinical effect of elbow anterolateral approach with internal fixation in the treatment of capitellum fractures.Methods 12 patients with capitellum fractures were divided into types according to Bryan-Morrey classification:type Ⅰ (n=8),type Ⅱ (n=2),type Ⅳ (n=2).Patients were treated with anterolateral approach with AO cannulated screw fixation.Curative effect was evaluated according to Broberg-Morrey scale.Imaging evaluation was conducted.Results No lateral collateral ligament injury,blood vessels or nerve injury were found in patients.Primary healings were obtained after operation.All patients were followed up for 8 to 26 months postoperatively (averaged 16 months).All fractures were healed at 5 to 9 weeks after operation (averaged 7.2 weeks).Postoperative elbow flexion and extension was averaged (127.2±12.8) ° and forearm rotation was averaged (154.6 ± 15.3)°.Postoperative Broberg-Morrey score was averaged 90.5.The 8 cases were excellent,3 cases good and 1 case poor.Conclusions Operation should be applicated according to fracture classification in the treatment of capitellum fractures.Anterolateral approach is better to expose the fracture,which is convenient for operation,and AO cannulated screw fixation can fix the fractures firmly.Clinical effect is satisfactory when taking early functional exercise for elbow joint.
9.Recordings of The Hippocampal Field Potentials and Unit Activity by Using Linear Silicon Electrode Array
Zhouyan FENG ; Lei GUANG ; Xiaojing ZHENG ; Jing WANG ; Shuhui LI
Progress in Biochemistry and Biophysics 2006;0(04):-
The rapid development of silicon microelectrode arrays provides an ideal means for the study of spatio-temporal features of neuronal activity in the brain. The stability of the linear silicon electrode array (LSEA) in recording neuronal potentials and its validity in recording unit activity are investigated. The experimental results showed that during the recording of field potentials in the hippocampal CA1 region of anesthetized rats, upward and downward movements of the recording probe for a distance of 200 ?m did not affect the orthordromic and antidromic evoked potentials significantly. The data indicated that the probe movements caused very small damage to the neurons, and the recording was stable. The contact sites that located in the pyramidal cell layer acquired CA1 neuronal unit activity validly. Different types of unit activity from independent neurons were easily distinguished in epochs of recording from a same recording site. These results demonstrated the features of the LSEA, including the facility of probe manipulation, the stability of recording and the abundance of data acquirement. The data will be helpful to the researchers involved in the application of microelectrode array for neuroscience researches.
10.Biocompatibility of Filtek~(TM) Z350 resin with dental pulp tissues of beagle dogs
Xiaojing HUANG ; Lishan LEI ; Sheng ZHONG ; Ming ZHANG
Chinese Journal of Tissue Engineering Research 2007;0(41):-
BACKGROUND:Nano-size inorganic filling greatly improves mechanic characteristic of composite resin.However,its effects on pulp tissue remain unclear.OBJECTIVE:To evaluate the biocompatibility of FiltekTM Z350 nano-composite resin on dog pulp tissue by means of histology observation.DESIGN,TIME AND SETTING:Randomized control animal experiment was performed at the animal experiment center of Fuzhou General Hospital,Nanjing Military Area Command of Chinese PLA from April 2007 to April 2008.MATERIALS:Sixty healthy teeth from three adult male beagle dogs were recruited in this study.METHODS:Buccal Class V deep cavities were prepared in beagle dogs,which were then divided into four groups at random.FiltekTM Z350 resin,Dyract AP compomer and TPH resin were used to restore the cavities in three testing groups and glass ionomer cement was used as control.All cavities were treated with Clearfil SE BOND before filling.Intact healthy teeth were used as blank control.MAIN OUTCOME MEASURES:The pulp condition of each tooth was studied histologically.The remaining dentine thickness of each cavity was measured.RESULTS:After 7 days,mild inflammatory response was observed in most of the specimens.After 30 and 90 days,normal histological characteristics were observed in almost all specimens except TPH resin group.The histological structure disturbance of dentin cell layer emerged in some specimens of TPH group,which was higher than other testing groups(P 0.05).CONCLUSION:FiltekTM Z350 nano-composite resin has similar biocompatibility as Dyract AP compomer and glass ionomer cement,better than TPH resin.