1.Experience of intensive rehabilitation training for school-age children with cerebral palsy
Chinese Journal of Rehabilitation Theory and Practice 2000;6(4):187-191
我们根据学生肢体、智力残疾的特点 ,经过不断摸索 ,反复修改 ,编制了一系列音乐文体康复操。这套操分上肢训练 ,下肢训练 ,颈、腰、脊柱训练和平衡、协调训练 4部分。通过实践 ,初见疗效。
4.Clinical Observation on 150 Patients with Diabetes Type Ⅱ Treated by Qiyao Xiaoke Capsule Combined with Metformin Hydrochloride Tablets:A Multi-centered Random-Controlled Study
Journal of Traditional Chinese Medicine 1993;0(06):-
Objective To observe the therapeutic effect of Qiyao Xiaoke Capsule(Capsule for Diabetes) on the diabetes type Ⅱ.Methods Totally 240 diabetes type Ⅱ patients were randomized into a treatment group(n=150),and a control group(n=90);and other 30 diabetes patients who didn't regularly take hypoglycemic drugs were set as opening group.The treatment group was administered Qiyao Xiaoke Capsule plus Metformin Hydrochloride Tablets,while the control group was prescribed Xiaokeling Capsule in addition to Metformin Hydrochloride Tablets,and the opening group was given Qiyao Xiaoke Capsule only,with a leading period of two weeks.The patients were treated for 4 weeks.Before treatment and at the end of the 4 weeks' treatment,the fasting blood glucose(FBG),2 hours postprandial blood glucose(2hPG),and glycosylated hemoglobin(HbA1c) of all groups were determined,and scores of TCM syndromes and symptoms were observed to evaluate the therapeutic effect.Results The total effective rate of the treatment group was 74.67%,of the control group 72.22%,and in the opening group 70.00%.Except for the 2hPG of the opening group,the FBG,2hPG and HbA1c of 3 groups were decreased(P
5.Humanized mouse models for liver disease research:a review
Acta Laboratorium Animalis Scientia Sinica 2014;(5):95-99
Liver diseases post great threats to human public health globally.Lacking of appropriate small animal models largely impeded the translational studies on human liver diseases, especially on viral hepatitis and related cirrhosis, hepatocellular carcinoma, etc.By human hepatocyte transplantation, the liver-humanized mice have significantly contribu-ted to the researches of human liver diseases.This review summarizes the currently widely used and representative human-ized mouse models, including uPA, FAH, TK-NOG, AFC8 mice and their applications in studies of human liver diseases.
6.Expression of survivin gene in the dysplasia of gastric mucous epithelium and the gastric carcinoma and its significance
Haijun REN ; Tianqing LIU ; Xiaohui YU
China Oncology 1998;0(01):-
Purpose:To study the expression of survivin a nd its relationship with the expression of bcl-2,p53,PCNA in the dysplasia of gastric mucous epithelium and gastric carcinoma.Methods:The expression of survivin,bcl-2,p53,PCNA was detected in 60 cases of gastric carcinoma, 30 cases of dysplasia of gastric mucous epithelim and 8 cases of normal gastric mucous tissue by using immunohistochemical SP method. Results:The positive rates of survivin were 10%,13%,80% and 82%, respectively, in mild, moderate and svere dysplasia and gastric carcinoma. The positive rates of survivin in mild and moderate dy splasia were significantly lower than in severe dysplasia and carcinoma (P0 05). There was a relationship between survivin gene expression with the invasive depth of gastric carcinoma. lymph node metastases and survival stage (P
7.Evaluation of the clinical result of elbow joint functional reconstruction with fork-like arthroplasty
Kaijing REN ; Xiaohui LI ; Jianhua YU
Orthopedic Journal of China 2006;0(13):-
0.05).[Conclusion]Elbow with fork-like arthroplasty gives good and excellent outcomes in most elbows with different diseases and can provide satisfactory improvement in elbow function for deseased elbows.
8.Effects of Survivin-T34A mutant on breast cancer cell in vitro and in vivo.
Xiaohui DENG ; Haiyan SONG ; Mingxin REN
Journal of Biomedical Engineering 2014;31(3):648-651
To study the effect of the proliferation and apoptosis of Survivin-T34A mutant on breast cancer MCF-7 cell, we adopted the method of cell culture in vitro to observe the proliferation and apoptosis of the cell. In the experiment, MCF-7 cells were randomly divided into three groups and transfected with normal saline, PORF-9-null and Survivin-T34A, respectively. Breast cancer nude mouse models were established to study anti-tumor effect of Survivin-T34A in vivo. The activity of the cells in the Survivin-T34A-transfected group was lower than that in PORF-9-null group. The increase of cell apoptosis was observed under electron microscopy, meanwhile the apoptotic rate was obviously higher than that in PORF-9-null control by flow cytometry. Tumor inhibition effects of the mouse which received the injection of Survivin-T34A intratumoral injection were apparent, and the inhibition ratio was as high as 47.1%. In conclusion, Survivin-T34A mutant has anti-tumor effect through efficiently inhibiting the growth of breast cancer MCF-7 cell and actively promoting apoptosis of cancer cells.
Animals
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Apoptosis
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Breast Neoplasms
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drug therapy
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pathology
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Humans
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Inhibitor of Apoptosis Proteins
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genetics
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pharmacology
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Injections, Intralesional
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Mice
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Mice, Nude
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Neoplasm Transplantation
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Transfection
9.Research on the effect of health education to women of childbearing age on knowledge of birth defects
Xiaohui REN ; Lifang LEI ; Xiulan LENG
Chinese Journal of Primary Medicine and Pharmacy 2012;19(6):864-865
ObjectiveTo evaluate the effect of health education to women of childbearing age on knowledge of birthdefents.MethodsRandomly selected 200 case of maternal pre-pregnancy check-up in the hospital outpatient department were divided into two groups,The observation group of 100 cases,100 cases of the control group.the control group received rule progestation knowledge education,the observation group enforce health education intervention,apply the way of questionnaire survey,and the results were statistically analyzed.ResultsThe observation group answer correct rate is obviously higher than the control group ( all P < 0.05 ).ConclusionTaking a variety of measures of health education for pregnant women during the physical examination for effective interventions,could significantly improve the population birth defects knowledge rate had positive significance to the prevention of birth defects.
10.Exploration to Innovation on Physical Teaching in Medical Colleges
Ya ZHOU ; Shehua REN ; Xiaohui LI
Chinese Journal of Medical Education Research 2005;0(06):-
Medical physics is the important basic for rapid development of model medical theory and technology.Innovation to physical education prompts the progress of high-level medical education.This study based on relevant educational practice will be beneficial to the progress of high-level medical education through primarily exploring the reforming of educational objective,educational model,educational instrument and educational teaching content.